CH660483A5 - Verfahren zur herstellung von cimetidin und seiner n-benzylderivate. - Google Patents

Verfahren zur herstellung von cimetidin und seiner n-benzylderivate. Download PDF

Info

Publication number
CH660483A5
CH660483A5 CH2014/86A CH201486A CH660483A5 CH 660483 A5 CH660483 A5 CH 660483A5 CH 2014/86 A CH2014/86 A CH 2014/86A CH 201486 A CH201486 A CH 201486A CH 660483 A5 CH660483 A5 CH 660483A5
Authority
CH
Switzerland
Prior art keywords
formula
compound
group
methyl
preparation
Prior art date
Application number
CH2014/86A
Other languages
German (de)
English (en)
Inventor
Borge Alhede
Niels Gelting
Herbert Preikschat
Finn Priess Clausen
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of CH660483A5 publication Critical patent/CH660483A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
CH2014/86A 1982-10-08 1983-12-15 Verfahren zur herstellung von cimetidin und seiner n-benzylderivate. CH660483A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8228782 1982-10-08

Publications (1)

Publication Number Publication Date
CH660483A5 true CH660483A5 (de) 1987-04-30

Family

ID=10533472

Family Applications (2)

Application Number Title Priority Date Filing Date
CH6694/83A CH659650A5 (de) 1982-10-08 1983-12-15 Oximinoverbindungen und imidazol-n-oxide fuer die herstellung von cimetidin und verfahren zu ihrer herstellung.
CH2014/86A CH660483A5 (de) 1982-10-08 1983-12-15 Verfahren zur herstellung von cimetidin und seiner n-benzylderivate.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH6694/83A CH659650A5 (de) 1982-10-08 1983-12-15 Oximinoverbindungen und imidazol-n-oxide fuer die herstellung von cimetidin und verfahren zu ihrer herstellung.

Country Status (18)

Country Link
JP (3) JPS5988472A (ru)
AU (1) AU560031B2 (ru)
BE (1) BE897952A (ru)
CA (1) CA1199030A (ru)
CH (2) CH659650A5 (ru)
DE (1) DE3336225A1 (ru)
DK (1) DK159309C (ru)
FI (1) FI79301C (ru)
FR (1) FR2534256B1 (ru)
GB (1) GB2129793B (ru)
IE (1) IE55946B1 (ru)
NL (1) NL191181C (ru)
NO (1) NO162018C (ru)
NZ (1) NZ205652A (ru)
PT (1) PT77468B (ru)
SE (2) SE449746B (ru)
ZA (1) ZA837237B (ru)
ZW (1) ZW21383A1 (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8618846D0 (en) * 1986-08-01 1986-09-10 Smithkline Beckman Corp Chemical process
JPH0623179B2 (ja) * 1986-09-01 1994-03-30 三井石油化学工業株式会社 シアノグアニジン誘導体及びその製造法
JPH0629234B2 (ja) * 1986-12-26 1994-04-20 三井石油化学工業株式会社 α−アシロキシケトン誘導体
JPH0623181B2 (ja) * 1987-02-17 1994-03-30 三井石油化学工業株式会社 シアノグアニジン誘導体及びその製造法
JPH0623180B2 (ja) * 1987-02-17 1994-03-30 三井石油化学工業株式会社 シアノグアニジン誘導体及びその製造法
JPS63208566A (ja) * 1987-02-23 1988-08-30 Mitsui Petrochem Ind Ltd グアニジン誘導体の製造法
JPS63208565A (ja) * 1987-02-23 1988-08-30 Mitsui Petrochem Ind Ltd グアニジン誘導体の製造方法
JP3006356U (ja) * 1994-04-12 1995-01-24 株式会社フコク 捩り振動吸収装置
CN115745893A (zh) * 2022-11-16 2023-03-07 西安近代化学研究所 一种合成2-氰基-5-芳基-1h-咪唑类化合物的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines

Also Published As

Publication number Publication date
SE8305508D0 (sv) 1983-10-06
NL8303351A (nl) 1984-05-01
SE449746B (sv) 1987-05-18
AU560031B2 (en) 1987-03-26
GB2129793A (en) 1984-05-23
FI833648A (fi) 1984-04-09
PT77468A (en) 1983-11-01
SE8305508L (sv) 1984-04-09
JPS62161767A (ja) 1987-07-17
DK451883A (da) 1984-04-09
NL191181B (nl) 1994-10-03
BE897952A (fr) 1984-01-30
JPS5988472A (ja) 1984-05-22
DE3336225C2 (ru) 1993-06-24
NZ205652A (en) 1987-05-29
PT77468B (en) 1986-02-12
DK159309C (da) 1991-03-11
JPH0579061B2 (ru) 1993-11-01
NO162018B (no) 1989-07-17
FI79301C (fi) 1989-12-11
DK159309B (da) 1990-10-01
NO162018C (no) 1989-10-25
SE8500176D0 (sv) 1985-01-15
SE8500176L (sv) 1985-01-15
DE3336225A1 (de) 1984-04-12
FR2534256B1 (ru) 1986-04-04
GB2129793B (en) 1986-03-12
CA1199030A (en) 1986-01-07
IE832198L (en) 1984-04-08
FI79301B (fi) 1989-08-31
GB8326767D0 (en) 1983-11-09
FR2534256A1 (ru) 1984-04-13
JPH0449539B2 (ru) 1992-08-11
DK451883D0 (da) 1983-09-30
ZA837237B (en) 1984-11-28
JPS62161766A (ja) 1987-07-17
AU1995683A (en) 1984-04-12
ZW21383A1 (en) 1984-01-18
CH659650A5 (de) 1987-02-13
IE55946B1 (en) 1991-02-27
NO833664L (no) 1984-04-09
FI833648A0 (fi) 1983-10-07
NL191181C (nl) 1995-03-01
SE459808B (sv) 1989-08-07

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