DE69905191T2 - Kondensierte pyridazinonverbindungen - Google Patents
Kondensierte pyridazinonverbindungenInfo
- Publication number
- DE69905191T2 DE69905191T2 DE69905191T DE69905191T DE69905191T2 DE 69905191 T2 DE69905191 T2 DE 69905191T2 DE 69905191 T DE69905191 T DE 69905191T DE 69905191 T DE69905191 T DE 69905191T DE 69905191 T2 DE69905191 T2 DE 69905191T2
- Authority
- DE
- Germany
- Prior art keywords
- group
- stands
- formula
- alkyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
- DJFWTWULJOZOGK-UHFFFAOYSA-N 3h-pyridazino[4,5-f][1,4]oxazepin-2-one Chemical compound O1C(=O)CN=CC2=CN=NC=C21 DJFWTWULJOZOGK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- DHZYXWMZLAKTQV-UHFFFAOYSA-N diazepin-3-one Chemical class O=C1C=CC=CN=N1 DHZYXWMZLAKTQV-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000006883 memory enhancing effect Effects 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- JKCJXAVMBWFTTC-UHFFFAOYSA-N thiazepine 1-oxide Chemical compound O=S1C=CC=CC=N1 JKCJXAVMBWFTTC-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9802585A HUP9802585A3 (en) | 1998-11-09 | 1998-11-09 | Pyridazinooxazepine, -thiazepine, -diazepine and thiazine derivatives and pharmaceutical compositions containing them |
| PCT/HU1999/000077 WO2000027851A1 (en) | 1998-11-09 | 1999-11-09 | Novel type condensed pyridazinone compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69905191D1 DE69905191D1 (de) | 2003-03-06 |
| DE69905191T2 true DE69905191T2 (de) | 2003-10-16 |
Family
ID=89997316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69905191T Expired - Fee Related DE69905191T2 (de) | 1998-11-09 | 1999-11-09 | Kondensierte pyridazinonverbindungen |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1129097B1 (de) |
| JP (1) | JP2002529470A (de) |
| KR (1) | KR100636515B1 (de) |
| AT (1) | ATE231873T1 (de) |
| AU (1) | AU762526B2 (de) |
| CA (1) | CA2350560C (de) |
| DE (1) | DE69905191T2 (de) |
| DK (1) | DK1129097T3 (de) |
| ES (1) | ES2192104T3 (de) |
| HU (1) | HUP9802585A3 (de) |
| PT (1) | PT1129097E (de) |
| WO (1) | WO2000027851A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0405034D0 (en) * | 2004-03-05 | 2004-04-07 | Novartis Ag | Organic compounds |
| AU2009274255A1 (en) | 2008-07-23 | 2010-01-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibitors of the plasmodial surface anion channel as antimalarials |
| WO2012142125A2 (en) | 2011-04-12 | 2012-10-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9411955D0 (en) * | 1994-06-15 | 1994-08-03 | Merck Sharp & Dohme | Therapeutic agents |
-
1998
- 1998-11-09 HU HU9802585A patent/HUP9802585A3/hu unknown
-
1999
- 1999-11-09 DK DK99971809T patent/DK1129097T3/da active
- 1999-11-09 ES ES99971809T patent/ES2192104T3/es not_active Expired - Lifetime
- 1999-11-09 AU AU14016/00A patent/AU762526B2/en not_active Ceased
- 1999-11-09 EP EP99971809A patent/EP1129097B1/de not_active Expired - Lifetime
- 1999-11-09 AT AT99971809T patent/ATE231873T1/de not_active IP Right Cessation
- 1999-11-09 JP JP2000581029A patent/JP2002529470A/ja active Pending
- 1999-11-09 KR KR1020017005304A patent/KR100636515B1/ko not_active IP Right Cessation
- 1999-11-09 WO PCT/HU1999/000077 patent/WO2000027851A1/en active IP Right Grant
- 1999-11-09 DE DE69905191T patent/DE69905191T2/de not_active Expired - Fee Related
- 1999-11-09 CA CA002350560A patent/CA2350560C/en not_active Expired - Fee Related
- 1999-11-09 PT PT99971809T patent/PT1129097E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69905191D1 (de) | 2003-03-06 |
| KR20010092424A (ko) | 2001-10-24 |
| EP1129097A1 (de) | 2001-09-05 |
| PT1129097E (pt) | 2003-06-30 |
| ES2192104T3 (es) | 2003-09-16 |
| HUP9802585A2 (hu) | 2000-08-28 |
| WO2000027851A1 (en) | 2000-05-18 |
| JP2002529470A (ja) | 2002-09-10 |
| AU762526B2 (en) | 2003-06-26 |
| EP1129097B1 (de) | 2003-01-29 |
| AU1401600A (en) | 2000-05-29 |
| HU9802585D0 (en) | 1999-01-28 |
| KR100636515B1 (ko) | 2006-10-18 |
| HUP9802585A3 (en) | 2000-09-28 |
| CA2350560A1 (en) | 2000-05-18 |
| CA2350560C (en) | 2006-10-31 |
| ATE231873T1 (de) | 2003-02-15 |
| DK1129097T3 (da) | 2003-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: IVAX DRUG RESEARCH INSTITUTE LTD., BUDAPEST, HU |
|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |