CH651014A5 - Basische ester von benzoesaeuren und von 2-thiophencarbonsaeuren, verfahren zu deren herstellung und arzneimittel, die diese ester enthalten. - Google Patents

Basische ester von benzoesaeuren und von 2-thiophencarbonsaeuren, verfahren zu deren herstellung und arzneimittel, die diese ester enthalten. Download PDF

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Publication number
CH651014A5
CH651014A5 CH5115/82A CH511582A CH651014A5 CH 651014 A5 CH651014 A5 CH 651014A5 CH 5115/82 A CH5115/82 A CH 5115/82A CH 511582 A CH511582 A CH 511582A CH 651014 A5 CH651014 A5 CH 651014A5
Authority
CH
Switzerland
Prior art keywords
formula
methyl
acids
pharmacologically acceptable
salts
Prior art date
Application number
CH5115/82A
Other languages
German (de)
English (en)
Inventor
Edith Rudinger
Xavier Perlia
Original Assignee
Pharmaton Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaton Sa filed Critical Pharmaton Sa
Priority to CH5115/82A priority Critical patent/CH651014A5/de
Priority to DE19833328494 priority patent/DE3328494A1/de
Priority to GB08321954A priority patent/GB2126219B/en
Priority to SE8304457A priority patent/SE8304457L/xx
Priority to FR838313762A priority patent/FR2532304B1/fr
Priority to IT48885/83A priority patent/IT1168211B/it
Priority to CA000435456A priority patent/CA1244020A/en
Priority to JP58157049A priority patent/JPS5998044A/ja
Publication of CH651014A5 publication Critical patent/CH651014A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH5115/82A 1982-08-27 1982-08-27 Basische ester von benzoesaeuren und von 2-thiophencarbonsaeuren, verfahren zu deren herstellung und arzneimittel, die diese ester enthalten. CH651014A5 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CH5115/82A CH651014A5 (de) 1982-08-27 1982-08-27 Basische ester von benzoesaeuren und von 2-thiophencarbonsaeuren, verfahren zu deren herstellung und arzneimittel, die diese ester enthalten.
DE19833328494 DE3328494A1 (de) 1982-08-27 1983-08-06 Basische ester von benzosauren und von 2-thio-phencarbonsaeuren, verfahren zu deren herstellung und arzneimittel, die diese ester enthalten
GB08321954A GB2126219B (en) 1982-08-27 1983-08-15 Basic esters of benzoic acids and 2-thio-phencarboxylic acids
SE8304457A SE8304457L (sv) 1982-08-27 1983-08-17 Basiska estrar av bensoesyrear och 2-tiofenkarbonsyror, forfarande for deras framstellning och lekemedel, som innehaller dessa estrar
FR838313762A FR2532304B1 (fr) 1982-08-27 1983-08-26 Esters basiques d'acides benzoiques et d'acides thiophenecarboxyliques-2, procedes de preparation de ceux-ci et medicaments en contenant
IT48885/83A IT1168211B (it) 1982-08-27 1983-08-26 Esteri di acidi benzoici e di acidi 2-tiofencarbossilici, procedimento per la loro produzione e medicamenti che li contengono
CA000435456A CA1244020A (en) 1982-08-27 1983-08-26 Basic esters of benzoic acids and 2-thio- phencarboxylic acids, processes for their preparation and a pharmacological composition containing these esters
JP58157049A JPS5998044A (ja) 1982-08-27 1983-08-27 安息香酸の塩基性エステルおよび２−チオフエンカルボン酸の塩基性エステル、それらの製造方法並びにこれらのエステルを含む医薬

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH5115/82A CH651014A5 (de) 1982-08-27 1982-08-27 Basische ester von benzoesaeuren und von 2-thiophencarbonsaeuren, verfahren zu deren herstellung und arzneimittel, die diese ester enthalten.

Publications (1)

Publication Number Publication Date
CH651014A5 true CH651014A5 (de) 1985-08-30

Family

ID=4288176

Family Applications (1)

Application Number Title Priority Date Filing Date
CH5115/82A CH651014A5 (de) 1982-08-27 1982-08-27 Basische ester von benzoesaeuren und von 2-thiophencarbonsaeuren, verfahren zu deren herstellung und arzneimittel, die diese ester enthalten.

Country Status (8)

Country Link
JP (1) JPS5998044A (it)
CA (1) CA1244020A (it)
CH (1) CH651014A5 (it)
DE (1) DE3328494A1 (it)
FR (1) FR2532304B1 (it)
GB (1) GB2126219B (it)
IT (1) IT1168211B (it)
SE (1) SE8304457L (it)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL19578C (it) * 1925-01-15
US2173827A (en) * 1936-10-26 1939-09-26 Pitman Moore Company Alkyl thio-substituted benzoic acid alkamine ester salts, intermediate and process of preparing same
GB525199A (en) * 1939-02-15 1940-08-23 Novocol Chemical M F G Co Inc Improvements in or relating to local anaesthetic bases and process of preparing same
US2372116A (en) * 1942-03-24 1945-03-20 Pierce Amino alcohol esters
US2383074A (en) * 1942-04-16 1945-08-21 American Cyanamid Co Alkamine derivatives of o-alkoxymethyl benzoic acid
US2404691A (en) * 1944-08-30 1946-07-23 Squibb & Sons Inc Chemical compounds
US2831016A (en) * 1954-05-27 1958-04-15 Univ Missouri beta-substituted aminoalkyl 2,6-dialkylsubstituted benzoates and method of making the same
US3047574A (en) * 1960-03-28 1962-07-31 Searle & Co 2-cyclohexyl-4-(2-hydroxyethyl)-3-methylmorpholine esters of substituted benzoic acids
FR2432516A1 (fr) * 1978-08-01 1980-02-29 Synthelabo Derives de phenyl-4 piperazino-ethanol et leur application en therapeutique

Also Published As

Publication number Publication date
FR2532304A1 (fr) 1984-03-02
FR2532304B1 (fr) 1989-05-19
IT1168211B (it) 1987-05-20
GB2126219B (en) 1987-05-28
IT8348885A0 (it) 1983-08-26
SE8304457D0 (sv) 1983-08-17
CA1244020A (en) 1988-11-01
DE3328494A1 (de) 1984-03-01
JPS5998044A (ja) 1984-06-06
GB8321954D0 (en) 1983-09-14
GB2126219A (en) 1984-03-21
SE8304457L (sv) 1984-02-28

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