FR2532304B1 - Esters basiques d'acides benzoiques et d'acides thiophenecarboxyliques-2, procedes de preparation de ceux-ci et medicaments en contenant - Google Patents

Esters basiques d'acides benzoiques et d'acides thiophenecarboxyliques-2, procedes de preparation de ceux-ci et medicaments en contenant

Info

Publication number
FR2532304B1
FR2532304B1 FR838313762A FR8313762A FR2532304B1 FR 2532304 B1 FR2532304 B1 FR 2532304B1 FR 838313762 A FR838313762 A FR 838313762A FR 8313762 A FR8313762 A FR 8313762A FR 2532304 B1 FR2532304 B1 FR 2532304B1
Authority
FR
France
Prior art keywords
acids
processes
preparation
thiophenecarboxylic
medicaments containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR838313762A
Other languages
English (en)
Other versions
FR2532304A1 (fr
Inventor
Edith Rudinger
Xavier Perlia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmaton SA
Original Assignee
Pharmaton SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaton SA filed Critical Pharmaton SA
Publication of FR2532304A1 publication Critical patent/FR2532304A1/fr
Application granted granted Critical
Publication of FR2532304B1 publication Critical patent/FR2532304B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR838313762A 1982-08-27 1983-08-26 Esters basiques d'acides benzoiques et d'acides thiophenecarboxyliques-2, procedes de preparation de ceux-ci et medicaments en contenant Expired FR2532304B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH5115/82A CH651014A5 (de) 1982-08-27 1982-08-27 Basische ester von benzoesaeuren und von 2-thiophencarbonsaeuren, verfahren zu deren herstellung und arzneimittel, die diese ester enthalten.

Publications (2)

Publication Number Publication Date
FR2532304A1 FR2532304A1 (fr) 1984-03-02
FR2532304B1 true FR2532304B1 (fr) 1989-05-19

Family

ID=4288176

Family Applications (1)

Application Number Title Priority Date Filing Date
FR838313762A Expired FR2532304B1 (fr) 1982-08-27 1983-08-26 Esters basiques d'acides benzoiques et d'acides thiophenecarboxyliques-2, procedes de preparation de ceux-ci et medicaments en contenant

Country Status (8)

Country Link
JP (1) JPS5998044A (fr)
CA (1) CA1244020A (fr)
CH (1) CH651014A5 (fr)
DE (1) DE3328494A1 (fr)
FR (1) FR2532304B1 (fr)
GB (1) GB2126219B (fr)
IT (1) IT1168211B (fr)
SE (1) SE8304457L (fr)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL19578C (fr) * 1925-01-15
US2173827A (en) * 1936-10-26 1939-09-26 Pitman Moore Company Alkyl thio-substituted benzoic acid alkamine ester salts, intermediate and process of preparing same
GB525199A (en) * 1939-02-15 1940-08-23 Novocol Chemical M F G Co Inc Improvements in or relating to local anaesthetic bases and process of preparing same
US2372116A (en) * 1942-03-24 1945-03-20 Pierce Amino alcohol esters
US2383074A (en) * 1942-04-16 1945-08-21 American Cyanamid Co Alkamine derivatives of o-alkoxymethyl benzoic acid
US2404691A (en) * 1944-08-30 1946-07-23 Squibb & Sons Inc Chemical compounds
US2831016A (en) * 1954-05-27 1958-04-15 Univ Missouri beta-substituted aminoalkyl 2,6-dialkylsubstituted benzoates and method of making the same
US3047574A (en) * 1960-03-28 1962-07-31 Searle & Co 2-cyclohexyl-4-(2-hydroxyethyl)-3-methylmorpholine esters of substituted benzoic acids
FR2432516A1 (fr) * 1978-08-01 1980-02-29 Synthelabo Derives de phenyl-4 piperazino-ethanol et leur application en therapeutique

Also Published As

Publication number Publication date
SE8304457L (sv) 1984-02-28
GB8321954D0 (en) 1983-09-14
CA1244020A (fr) 1988-11-01
GB2126219A (en) 1984-03-21
CH651014A5 (de) 1985-08-30
IT1168211B (it) 1987-05-20
DE3328494A1 (de) 1984-03-01
FR2532304A1 (fr) 1984-03-02
SE8304457D0 (sv) 1983-08-17
JPS5998044A (ja) 1984-06-06
GB2126219B (en) 1987-05-28
IT8348885A0 (it) 1983-08-26

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Legal Events

Date Code Title Description
ST Notification of lapse