GB2126219B - Basic esters of benzoic acids and 2-thio-phencarboxylic acids - Google Patents

Basic esters of benzoic acids and 2-thio-phencarboxylic acids

Info

Publication number
GB2126219B
GB2126219B GB08321954A GB8321954A GB2126219B GB 2126219 B GB2126219 B GB 2126219B GB 08321954 A GB08321954 A GB 08321954A GB 8321954 A GB8321954 A GB 8321954A GB 2126219 B GB2126219 B GB 2126219B
Authority
GB
United Kingdom
Prior art keywords
acids
phencarboxylic
thio
basic esters
benzoic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08321954A
Other versions
GB2126219A (en
GB8321954D0 (en
Inventor
Edith Rudinger
Xavier Perlia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmaton SA
Original Assignee
Pharmaton SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaton SA filed Critical Pharmaton SA
Publication of GB8321954D0 publication Critical patent/GB8321954D0/en
Publication of GB2126219A publication Critical patent/GB2126219A/en
Application granted granted Critical
Publication of GB2126219B publication Critical patent/GB2126219B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
GB08321954A 1982-08-27 1983-08-15 Basic esters of benzoic acids and 2-thio-phencarboxylic acids Expired GB2126219B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH5115/82A CH651014A5 (en) 1982-08-27 1982-08-27 BASIC ESTERS OF BENZOESIC ACIDS AND OF 2-THIOPHENIC CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE ESTERS.

Publications (3)

Publication Number Publication Date
GB8321954D0 GB8321954D0 (en) 1983-09-14
GB2126219A GB2126219A (en) 1984-03-21
GB2126219B true GB2126219B (en) 1987-05-28

Family

ID=4288176

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08321954A Expired GB2126219B (en) 1982-08-27 1983-08-15 Basic esters of benzoic acids and 2-thio-phencarboxylic acids

Country Status (8)

Country Link
JP (1) JPS5998044A (en)
CA (1) CA1244020A (en)
CH (1) CH651014A5 (en)
DE (1) DE3328494A1 (en)
FR (1) FR2532304B1 (en)
GB (1) GB2126219B (en)
IT (1) IT1168211B (en)
SE (1) SE8304457L (en)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL19578C (en) * 1925-01-15
US2173827A (en) * 1936-10-26 1939-09-26 Pitman Moore Company Alkyl thio-substituted benzoic acid alkamine ester salts, intermediate and process of preparing same
GB525199A (en) * 1939-02-15 1940-08-23 Novocol Chemical M F G Co Inc Improvements in or relating to local anaesthetic bases and process of preparing same
US2372116A (en) * 1942-03-24 1945-03-20 Pierce Amino alcohol esters
US2383074A (en) * 1942-04-16 1945-08-21 American Cyanamid Co Alkamine derivatives of o-alkoxymethyl benzoic acid
US2404691A (en) * 1944-08-30 1946-07-23 Squibb & Sons Inc Chemical compounds
US2831016A (en) * 1954-05-27 1958-04-15 Univ Missouri beta-substituted aminoalkyl 2,6-dialkylsubstituted benzoates and method of making the same
US3047574A (en) * 1960-03-28 1962-07-31 Searle & Co 2-cyclohexyl-4-(2-hydroxyethyl)-3-methylmorpholine esters of substituted benzoic acids
FR2432516A1 (en) * 1978-08-01 1980-02-29 Synthelabo 4-Phenyl-piperazino-ethanol derivs. - having CNS activity, useful for treating anxiety and depression

Also Published As

Publication number Publication date
CH651014A5 (en) 1985-08-30
IT8348885A0 (en) 1983-08-26
FR2532304A1 (en) 1984-03-02
CA1244020A (en) 1988-11-01
FR2532304B1 (en) 1989-05-19
SE8304457D0 (en) 1983-08-17
SE8304457L (en) 1984-02-28
JPS5998044A (en) 1984-06-06
IT1168211B (en) 1987-05-20
DE3328494A1 (en) 1984-03-01
GB2126219A (en) 1984-03-21
GB8321954D0 (en) 1983-09-14

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19950815