CH616160A5 - Process for the preparation of novel compounds which affect gastric acid secretion - Google Patents

Process for the preparation of novel compounds which affect gastric acid secretion Download PDF

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Publication number
CH616160A5
CH616160A5 CH182975A CH182975A CH616160A5 CH 616160 A5 CH616160 A5 CH 616160A5 CH 182975 A CH182975 A CH 182975A CH 182975 A CH182975 A CH 182975A CH 616160 A5 CH616160 A5 CH 616160A5
Authority
CH
Switzerland
Prior art keywords
benzimidazole
pyridylmethylthio
hydrogen
formula
het
Prior art date
Application number
CH182975A
Other languages
German (de)
English (en)
Inventor
Peder Bernhard Berntsson
Stig Ake Ingemar Carlsson
Lars Erik Garberg
Ulf Krister Junggren
Sven Erik Sjoestrand
Gunhild Wika Von Wittk Sundell
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of CH616160A5 publication Critical patent/CH616160A5/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
CH182975A 1974-02-18 1975-02-14 Process for the preparation of novel compounds which affect gastric acid secretion CH616160A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7402101A SE418966B (sv) 1974-02-18 1974-02-18 Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan

Publications (1)

Publication Number Publication Date
CH616160A5 true CH616160A5 (en) 1980-03-14

Family

ID=20320233

Family Applications (1)

Application Number Title Priority Date Filing Date
CH182975A CH616160A5 (en) 1974-02-18 1975-02-14 Process for the preparation of novel compounds which affect gastric acid secretion

Country Status (23)

Country Link
JP (1) JPS5924157B2 (fr)
AT (1) AT343659B (fr)
AU (1) AU499639B2 (fr)
BE (1) BE825655A (fr)
CA (1) CA1060448A (fr)
CH (1) CH616160A5 (fr)
CS (1) CS194715B2 (fr)
DD (1) DD119422A5 (fr)
DE (1) DE2504252A1 (fr)
DK (1) DK141122B (fr)
FI (1) FI59590C (fr)
FR (1) FR2261007B1 (fr)
GB (1) GB1500043A (fr)
HK (1) HK67080A (fr)
HU (1) HU172141B (fr)
IE (1) IE40858B1 (fr)
LU (1) LU71872A1 (fr)
MY (1) MY8100208A (fr)
NL (1) NL7501917A (fr)
NO (1) NO142401C (fr)
SE (1) SE418966B (fr)
SU (1) SU795476A3 (fr)
ZA (1) ZA75558B (fr)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
JPS5364103A (en) * 1976-09-24 1978-06-08 Hitachi Ltd Waste heat recovery boiler
IN148930B (fr) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4343805A (en) * 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
DE3047388A1 (de) * 1980-12-16 1982-07-15 Basf Ag, 6700 Ludwigshafen Isatogenderivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
US4503139A (en) * 1983-05-09 1985-03-05 Polaroid Corporation Photographic products and processes and novel compounds
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
US4767770A (en) * 1984-06-18 1988-08-30 Eli Lilly And Company Method of inhibiting aromatase
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FR2593178B1 (fr) * 1986-01-20 1988-04-29 Esteve Labor Dr Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
SE8600658D0 (sv) * 1986-02-14 1986-02-14 Haessle Ab Novel composition of matter
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
NZ222495A (en) 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
SE8604998D0 (sv) 1986-11-21 1986-11-21 Haessle Ab Novel pharmacological compounds
WO1989005643A1 (fr) * 1987-12-18 1989-06-29 Pfizer Inc. Acides carboxyliques de quinoline a substitution heterocyclique
JPH021280U (fr) * 1988-06-14 1990-01-08
US5175286A (en) * 1988-09-20 1992-12-29 Hisamitsu Pharmaceutical Co., Inc. Dibenz[b,e]oxepin derivatives
EG19302A (en) * 1988-12-22 1994-11-30 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804628D0 (sv) 1988-12-22 1988-12-22 Ab Haessle New compounds
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
JPH0347053U (fr) * 1989-09-16 1991-04-30
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5049674A (en) 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
AU2003226706A1 (en) * 2002-03-27 2003-10-08 Altana Pharma Ag Novel alkoxypyridine-derivatives
ES2273225T3 (es) * 2003-02-25 2007-05-01 Altana Pharma Ag Derivados de imidazo (4,5-b) quinolina y su uso como inhibidores de la no-sintasa.
EA200600601A1 (ru) * 2003-10-01 2006-10-27 Алтана Фарма Аг Производные аминопиридина в качестве ингибиторов индуцируемой no-синтазы
AU2004276014A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
BRPI0414873A (pt) * 2003-10-01 2006-12-12 Altana Pharma Ag derivados de imidazopiridina como inibidores de no-sintase induzìveis
NZ546437A (en) 2003-10-01 2009-09-25 Altana Pharma Ag Imidazopyridine-derivatives as inducible NO-synthase inhibitors
JP2007507463A (ja) 2003-10-01 2007-03-29 アルタナ ファルマ アクチエンゲゼルシャフト 誘導性NOシンターゼ阻害剤としてのイミダゾ[4,5−b]ピリジン誘導体
EP2070923A1 (fr) 2007-12-11 2009-06-17 Bayer CropScience AG Iminohétérocycles insecticides
EP2576540B1 (fr) * 2010-05-26 2019-09-04 Sunovion Pharmaceuticals Inc. Composés hétéroarylés et leurs procédés d'utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (fr) * 1968-10-21 1971-06-03

Also Published As

Publication number Publication date
SE418966B (sv) 1981-07-06
DD119422A5 (fr) 1976-04-20
FR2261007B1 (fr) 1978-11-24
CA1060448A (fr) 1979-08-14
ATA113775A (de) 1977-10-15
JPS5924157B2 (ja) 1984-06-07
BE825655A (fr) 1975-08-18
FR2261007A1 (fr) 1975-09-12
GB1500043A (en) 1978-02-08
CS194715B2 (en) 1979-12-31
NO142401C (no) 1980-08-13
SU795476A3 (ru) 1981-01-07
IE40858B1 (en) 1979-08-29
MY8100208A (en) 1981-12-31
ZA75558B (en) 1976-01-28
AU499639B2 (en) 1979-04-26
AU7820675A (en) 1976-08-19
LU71872A1 (fr) 1975-12-09
IE40858L (en) 1975-08-18
NL7501917A (nl) 1975-08-20
DK141122B (da) 1980-01-21
FI59590B (fi) 1981-05-29
DK141122C (fr) 1980-07-07
SE7402101L (fr) 1975-08-19
HK67080A (en) 1980-12-05
NO142401B (no) 1980-05-05
DE2504252C2 (fr) 1989-02-02
NO750541L (fr) 1975-08-19
AT343659B (de) 1978-06-12
JPS50116474A (en) 1975-09-11
FI59590C (fi) 1981-09-10
FI750421A (fr) 1975-08-19
HU172141B (hu) 1978-06-28
DE2504252A1 (de) 1975-08-21
DK54075A (fr) 1975-10-20

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