BRPI0414873A - derivados de imidazopiridina como inibidores de no-sintase induzìveis - Google Patents

derivados de imidazopiridina como inibidores de no-sintase induzìveis

Info

Publication number
BRPI0414873A
BRPI0414873A BRPI0414873-8A BRPI0414873A BRPI0414873A BR PI0414873 A BRPI0414873 A BR PI0414873A BR PI0414873 A BRPI0414873 A BR PI0414873A BR PI0414873 A BRPI0414873 A BR PI0414873A
Authority
BR
Brazil
Prior art keywords
inducible
synthase inhibitors
imidazopyridine derivatives
imidazopyridine
derivatives
Prior art date
Application number
BRPI0414873-8A
Other languages
English (en)
Inventor
Thomas Fuchss
Thomas Martin
Rainer Boer
Andreas Strub
Manfrid Eltze
Martin Lehner
Degenhard Marx
Wolf-Ruediger Ulrich
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of BRPI0414873A publication Critical patent/BRPI0414873A/pt

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)

Abstract

"DERIVADOS DE IMIDAZOPIRIDINA COMO INIBIDORES DE NO-SINTASE INDUZìVEIS". Os compostos da fórmula I onde R1, R2, Het1 e A possuem os significados conforme fornecidos na descrição são novos inibidores eficazes de INOS.
BRPI0414873-8A 2003-10-01 2004-09-30 derivados de imidazopiridina como inibidores de no-sintase induzìveis BRPI0414873A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03022064 2003-10-01
PCT/EP2004/052376 WO2005030769A1 (en) 2003-10-01 2004-09-30 Imidazopyridine-derivatives as inducible no-synthase inhibitors

Publications (1)

Publication Number Publication Date
BRPI0414873A true BRPI0414873A (pt) 2006-12-12

Family

ID=34384572

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414873-8A BRPI0414873A (pt) 2003-10-01 2004-09-30 derivados de imidazopiridina como inibidores de no-sintase induzìveis

Country Status (17)

Country Link
US (1) US20080125460A1 (pt)
EP (1) EP1673371B1 (pt)
JP (1) JP2007507465A (pt)
KR (1) KR20060092222A (pt)
CN (1) CN1856494A (pt)
AT (1) ATE403655T1 (pt)
AU (1) AU2004276013A1 (pt)
BR (1) BRPI0414873A (pt)
CA (1) CA2540242A1 (pt)
DE (1) DE602004015628D1 (pt)
EA (1) EA200600609A1 (pt)
IL (1) IL173809A0 (pt)
MX (1) MXPA06003554A (pt)
NO (1) NO20061316L (pt)
RS (1) RS20060195A (pt)
WO (1) WO2005030769A1 (pt)
ZA (1) ZA200601552B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100415746C (zh) 2003-10-01 2008-09-03 奥坦纳医药公司 氨基吡啶衍生物作为可诱导的no-合酶抑制剂
CA2540239A1 (en) 2003-10-01 2005-04-07 Altana Pharma Ag Imidazo(4,5-b)pyridine-derivatives as inducible no-synthase inhibitors
US7468377B2 (en) 2003-10-01 2008-12-23 Altana Pharma Ag Imidazopyridine-derivatives as inductible no-synthase inhibitors
AU2004276014A1 (en) 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
WO2009029625A1 (en) * 2007-08-27 2009-03-05 Kalypsys, Inc. 4- [heterocyclyl-methyl] -8-fluoro-quinolin-2-ones useful as nitric oxide synthase inhibitors
EP2576540B1 (en) * 2010-05-26 2019-09-04 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof
JP6302480B2 (ja) * 2012-11-29 2018-03-28 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． 中枢神経系疾患の治療に有用なトリアゾロ−ピラジン誘導体
GB201512635D0 (en) 2015-07-17 2015-08-26 Ucl Business Plc Uses of therapeutic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
AUPP873799A0 (en) * 1999-02-17 1999-03-11 Fujisawa Pharmaceutical Co., Ltd. Pyridine compounds
DE60318826T2 (de) * 2002-03-27 2009-01-22 Nycomed Gmbh Alkoxypyridinderivate

Also Published As

Publication number Publication date
JP2007507465A (ja) 2007-03-29
DE602004015628D1 (de) 2008-09-18
KR20060092222A (ko) 2006-08-22
EP1673371B1 (en) 2008-08-06
EA200600609A1 (ru) 2006-10-27
AU2004276013A1 (en) 2005-04-07
US20080125460A1 (en) 2008-05-29
ATE403655T1 (de) 2008-08-15
CN1856494A (zh) 2006-11-01
MXPA06003554A (es) 2006-06-05
WO2005030769A1 (en) 2005-04-07
RS20060195A (en) 2008-08-07
EP1673371A1 (en) 2006-06-28
CA2540242A1 (en) 2005-04-07
ZA200601552B (en) 2007-04-25
IL173809A0 (en) 2006-07-05
NO20061316L (no) 2006-03-23

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.