CS194715B2 - Method of producing new derivatives of 2-/2-heterocyclylmethylthio/benzimidazole - Google Patents

Method of producing new derivatives of 2-/2-heterocyclylmethylthio/benzimidazole

Info

Publication number
CS194715B2
CS194715B2 CS75987A CS98775A CS194715B2 CS 194715 B2 CS194715 B2 CS 194715B2 CS 75987 A CS75987 A CS 75987A CS 98775 A CS98775 A CS 98775A CS 194715 B2 CS194715 B2 CS 194715B2
Authority
CS
Czechoslovakia
Prior art keywords
heterocyclylmethylthio
benzimidazole
producing new
new derivatives
derivatives
Prior art date
Application number
CS75987A
Other languages
Czech (cs)
English (en)
Inventor
Peder B Berntsson
Stig A Carlsson
Lars E Garberg
Ulf K Junggren
Sven E Sjoestrand
Wittken Sundell G Von
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of CS194715B2 publication Critical patent/CS194715B2/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
CS75987A 1974-02-18 1975-02-14 Method of producing new derivatives of 2-/2-heterocyclylmethylthio/benzimidazole CS194715B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7402101A SE418966B (sv) 1974-02-18 1974-02-18 Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan

Publications (1)

Publication Number Publication Date
CS194715B2 true CS194715B2 (en) 1979-12-31

Family

ID=20320233

Family Applications (1)

Application Number Title Priority Date Filing Date
CS75987A CS194715B2 (en) 1974-02-18 1975-02-14 Method of producing new derivatives of 2-/2-heterocyclylmethylthio/benzimidazole

Country Status (23)

Country Link
JP (1) JPS5924157B2 (fr)
AT (1) AT343659B (fr)
AU (1) AU499639B2 (fr)
BE (1) BE825655A (fr)
CA (1) CA1060448A (fr)
CH (1) CH616160A5 (fr)
CS (1) CS194715B2 (fr)
DD (1) DD119422A5 (fr)
DE (1) DE2504252A1 (fr)
DK (1) DK141122B (fr)
FI (1) FI59590C (fr)
FR (1) FR2261007B1 (fr)
GB (1) GB1500043A (fr)
HK (1) HK67080A (fr)
HU (1) HU172141B (fr)
IE (1) IE40858B1 (fr)
LU (1) LU71872A1 (fr)
MY (1) MY8100208A (fr)
NL (1) NL7501917A (fr)
NO (1) NO142401C (fr)
SE (1) SE418966B (fr)
SU (1) SU795476A3 (fr)
ZA (1) ZA75558B (fr)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
JPS5364103A (en) * 1976-09-24 1978-06-08 Hitachi Ltd Waste heat recovery boiler
IN148930B (fr) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4343805A (en) * 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
DE3047388A1 (de) * 1980-12-16 1982-07-15 Basf Ag, 6700 Ludwigshafen Isatogenderivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
US4503139A (en) * 1983-05-09 1985-03-05 Polaroid Corporation Photographic products and processes and novel compounds
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
US4767770A (en) * 1984-06-18 1988-08-30 Eli Lilly And Company Method of inhibiting aromatase
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
FR2593178B1 (fr) * 1986-01-20 1988-04-29 Esteve Labor Dr Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
SE8600658D0 (sv) * 1986-02-14 1986-02-14 Haessle Ab Novel composition of matter
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
NZ222495A (en) 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
SE8604998D0 (sv) 1986-11-21 1986-11-21 Haessle Ab Novel pharmacological compounds
WO1989005643A1 (fr) * 1987-12-18 1989-06-29 Pfizer Inc. Acides carboxyliques de quinoline a substitution heterocyclique
JPH021280U (fr) * 1988-06-14 1990-01-08
US5175286A (en) * 1988-09-20 1992-12-29 Hisamitsu Pharmaceutical Co., Inc. Dibenz[b,e]oxepin derivatives
EG19302A (en) * 1988-12-22 1994-11-30 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804628D0 (sv) 1988-12-22 1988-12-22 Ab Haessle New compounds
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
JPH0347053U (fr) * 1989-09-16 1991-04-30
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5049674A (en) 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
AU2003226706A1 (en) * 2002-03-27 2003-10-08 Altana Pharma Ag Novel alkoxypyridine-derivatives
ES2273225T3 (es) * 2003-02-25 2007-05-01 Altana Pharma Ag Derivados de imidazo (4,5-b) quinolina y su uso como inhibidores de la no-sintasa.
EA200600601A1 (ru) * 2003-10-01 2006-10-27 Алтана Фарма Аг Производные аминопиридина в качестве ингибиторов индуцируемой no-синтазы
AU2004276014A1 (en) * 2003-10-01 2005-04-07 Altana Pharma Ag Imidazopyridine-derivatives as inducible no-synthase inhibitors
BRPI0414873A (pt) * 2003-10-01 2006-12-12 Altana Pharma Ag derivados de imidazopiridina como inibidores de no-sintase induzìveis
NZ546437A (en) 2003-10-01 2009-09-25 Altana Pharma Ag Imidazopyridine-derivatives as inducible NO-synthase inhibitors
JP2007507463A (ja) 2003-10-01 2007-03-29 アルタナ　ファルマ　アクチエンゲゼルシャフト 誘導性ＮＯシンターゼ阻害剤としてのイミダゾ［４，５−ｂ］ピリジン誘導体
EP2070923A1 (fr) 2007-12-11 2009-06-17 Bayer CropScience AG Iminohétérocycles insecticides
EP2576540B1 (fr) * 2010-05-26 2019-09-04 Sunovion Pharmaceuticals Inc. Composés hétéroarylés et leurs procédés d'utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (fr) * 1968-10-21 1971-06-03

Also Published As

Publication number Publication date
SE418966B (sv) 1981-07-06
DD119422A5 (fr) 1976-04-20
FR2261007B1 (fr) 1978-11-24
CA1060448A (fr) 1979-08-14
ATA113775A (de) 1977-10-15
JPS5924157B2 (ja) 1984-06-07
BE825655A (fr) 1975-08-18
FR2261007A1 (fr) 1975-09-12
GB1500043A (en) 1978-02-08
NO142401C (no) 1980-08-13
SU795476A3 (ru) 1981-01-07
IE40858B1 (en) 1979-08-29
MY8100208A (en) 1981-12-31
ZA75558B (en) 1976-01-28
AU499639B2 (en) 1979-04-26
AU7820675A (en) 1976-08-19
LU71872A1 (fr) 1975-12-09
IE40858L (en) 1975-08-18
NL7501917A (nl) 1975-08-20
DK141122B (da) 1980-01-21
FI59590B (fi) 1981-05-29
DK141122C (fr) 1980-07-07
SE7402101L (fr) 1975-08-19
HK67080A (en) 1980-12-05
NO142401B (no) 1980-05-05
DE2504252C2 (fr) 1989-02-02
NO750541L (fr) 1975-08-19
AT343659B (de) 1978-06-12
JPS50116474A (en) 1975-09-11
FI59590C (fi) 1981-09-10
CH616160A5 (en) 1980-03-14
FI750421A (fr) 1975-08-19
HU172141B (hu) 1978-06-28
DE2504252A1 (de) 1975-08-21
DK54075A (fr) 1975-10-20

Similar Documents

Publication Publication Date Title
CS194715B2 (en) Method of producing new derivatives of 2-/2-heterocyclylmethylthio/benzimidazole
BG24052A3 (en) Method of preparing benzimidazoles
CS194221B2 (en) Method of producing novel derivatives of aryl-and aralkylimidazole
CS189731B2 (en) Method of producing new derivatives of 3-aminoindazolcarboxylic acid
BG27744A3 (en) Method of obtaining of hynazolin derivatives
CS190478B2 (en) Method of producing novel biphenylyl derivatives
CS188235B2 (en) Method of producing new derivatives ryfamicine
CS191264B2 (en) Method of producing new pyridobenzodiazepinones
CS188131B2 (en) Method of producing novel o-hydroxybutyrophenone derivatives
CS189726B2 (en) Method of producing new amines
CS192518B2 (en) Method of producing derivatives of 3-cinnolincarboxylic acid
CS189020B2 (en) Method of producing new derivatives of triaminoandrostane
JPS51125088A (en) Preparation method of new benzhydryloxyyalkylamine derivatives
CS189712B2 (en) Method of producing novel derivatives of triazole
CS191940B2 (en) Method of producing derivatives of piperazine
CS185675B2 (en) Method of producing 7-amino-delta up3-cephem derivatives
CS183825B2 (en) Method of producing new derivatives of phenoxypropylami
CS182294B2 (en) Method of producing new pharmacolagic corticoides
ZA752432B (en) Method for the preparation of chromene derivatives
CS181691B2 (en) Method of producing new derivatives of phenoxypropylamine
YU108181A (en) Process for obtaining new benzimidazole derivatives
CS194750B2 (en) Method of producing new derivatives of triazole
CS192532B2 (en) Method of producing derivatives of alpha-acyl-ureido-cephalosporin
CS185700B2 (en) Method of producing new amines
PL193419A1 (pl) Sposob wytwarzania nowych pochodnych chinazoliny