CA3079011A1 - Detection of symmetrical dimethylarginine - Google Patents

Detection of symmetrical dimethylarginine Download PDF

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Publication number
CA3079011A1
CA3079011A1 CA3079011A CA3079011A CA3079011A1 CA 3079011 A1 CA3079011 A1 CA 3079011A1 CA 3079011 A CA3079011 A CA 3079011A CA 3079011 A CA3079011 A CA 3079011A CA 3079011 A1 CA3079011 A1 CA 3079011A1
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CA
Canada
Prior art keywords
sdma
antibody
affinity
protein
analog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3079011A
Other languages
English (en)
French (fr)
Inventor
Hongzhi Xie
Sreenivasa Rao RAMISETTY
Murthy Vsn Yerramilli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Idexx Laboratories Inc
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Idexx Laboratories Inc
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Application filed by Idexx Laboratories Inc filed Critical Idexx Laboratories Inc
Publication of CA3079011A1 publication Critical patent/CA3079011A1/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/563Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3079011A 2017-10-19 2018-10-19 Detection of symmetrical dimethylarginine Pending CA3079011A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762574592P 2017-10-19 2017-10-19
US62/574,592 2017-10-19
US201762599117P 2017-12-15 2017-12-15
US62/599,117 2017-12-15
PCT/US2018/056687 WO2019079707A1 (en) 2017-10-19 2018-10-19 SYMMETRIC DIMETHYLARGININE DETECTION

Publications (1)

Publication Number Publication Date
CA3079011A1 true CA3079011A1 (en) 2019-04-25

Family

ID=66170983

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3079011A Pending CA3079011A1 (en) 2017-10-19 2018-10-19 Detection of symmetrical dimethylarginine

Country Status (11)

Country Link
US (2) US11422136B2 (https=)
EP (1) EP3697499A4 (https=)
JP (1) JP7398366B2 (https=)
KR (2) KR102902843B1 (https=)
CN (1) CN111246918B (https=)
AU (1) AU2018351349B2 (https=)
CA (1) CA3079011A1 (https=)
MX (1) MX2020003523A (https=)
TW (1) TWI831753B (https=)
WO (1) WO2019079707A1 (https=)
ZA (1) ZA202002415B (https=)

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AU2018351349B2 (en) 2017-10-19 2025-08-14 Idexx Laboratories, Inc. Detection of symmetrical dimethylarginine
US10745492B1 (en) * 2019-04-03 2020-08-18 Ark Diagnostics, Inc. Antibodies to symmetrically dimethylated arginine analytes and use thereof
WO2021046339A1 (en) 2019-09-05 2021-03-11 The Regents Of The University Of California Noninvasive method to quantify kidney function and functional decline
CN113125697B (zh) * 2019-12-31 2024-03-26 科美博阳诊断技术(上海)有限公司 一种睾酮均相化学发光检测试剂盒及其应用
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WO2025205769A1 (ja) * 2024-03-26 2025-10-02 富士フイルム株式会社 α-アミラーゼと対称性ジメチルアルギニンとのコンジュゲート、およびその応用
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Also Published As

Publication number Publication date
CN111246918A (zh) 2020-06-05
EP3697499A4 (en) 2021-07-21
US20190120856A1 (en) 2019-04-25
EP3697499A1 (en) 2020-08-26
WO2019079707A1 (en) 2019-04-25
JP7398366B2 (ja) 2023-12-14
BR112020007150A2 (pt) 2020-09-24
JP2021500551A (ja) 2021-01-07
KR20250034534A (ko) 2025-03-11
KR102902843B1 (ko) 2025-12-19
CN111246918B (zh) 2024-06-14
TW201923349A (zh) 2019-06-16
US11422136B2 (en) 2022-08-23
MX2020003523A (es) 2020-07-22
KR20200073259A (ko) 2020-06-23
TWI831753B (zh) 2024-02-11
US20230102277A1 (en) 2023-03-30
AU2018351349B2 (en) 2025-08-14
ZA202002415B (en) 2023-09-27
AU2018351349A1 (en) 2020-04-23

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