CA2791654C - Ultra-sensitive detection of molecules or particles using beads or other capture objects - Google Patents

Ultra-sensitive detection of molecules or particles using beads or other capture objects Download PDF

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Publication number
CA2791654C
CA2791654C CA2791654A CA2791654A CA2791654C CA 2791654 C CA2791654 C CA 2791654C CA 2791654 A CA2791654 A CA 2791654A CA 2791654 A CA2791654 A CA 2791654A CA 2791654 C CA2791654 C CA 2791654C
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capture
analyte
locations
analyte molecule
capture objects
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French (fr)
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CA2791654A1 (en
Inventor
David C. Duffy
David M. Rissin
David R. Walt
David Fournier
Cheuk Kan
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Quanterix Corp
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Quanterix Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2791654A 2010-03-01 2011-03-01 Ultra-sensitive detection of molecules or particles using beads or other capture objects Active CA2791654C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US30914110P 2010-03-01 2010-03-01
US61/309,141 2010-03-01
US12/731,130 2010-03-24
US12/731,130 US8236574B2 (en) 2010-03-01 2010-03-24 Ultra-sensitive detection of molecules or particles using beads or other capture objects
PCT/US2011/026645 WO2011109364A2 (en) 2010-03-01 2011-03-01 Ultra-sensitive detection of molecules or particles using beads or other capture objects

Publications (2)

Publication Number Publication Date
CA2791654A1 CA2791654A1 (en) 2011-09-09
CA2791654C true CA2791654C (en) 2014-12-09

Family

ID=44505589

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2791654A Active CA2791654C (en) 2010-03-01 2011-03-01 Ultra-sensitive detection of molecules or particles using beads or other capture objects

Country Status (7)

Country Link
US (8) US8236574B2 (https=)
EP (4) EP2995955B1 (https=)
JP (2) JP5551798B2 (https=)
CN (2) CN104820092B (https=)
CA (1) CA2791654C (https=)
ES (3) ES2659786T3 (https=)
WO (1) WO2011109364A2 (https=)

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* Cited by examiner, † Cited by third party
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