CA2741052C - Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration - Google Patents
Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration Download PDFInfo
- Publication number
- CA2741052C CA2741052C CA2741052A CA2741052A CA2741052C CA 2741052 C CA2741052 C CA 2741052C CA 2741052 A CA2741052 A CA 2741052A CA 2741052 A CA2741052 A CA 2741052A CA 2741052 C CA2741052 C CA 2741052C
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- pharmaceutical composition
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- carbon atoms
- poloxamer
- imiquimod
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- 238000000034 method Methods 0.000 claims abstract description 33
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- 201000003146 cystitis Diseases 0.000 claims abstract description 14
- DOUYETYNHWVLEO-UHFFFAOYSA-N imiquimod Chemical compound C1=CC=CC2=C3N(CC(C)C)C=NC3=C(N)N=C21 DOUYETYNHWVLEO-UHFFFAOYSA-N 0.000 claims description 363
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- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims description 339
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Landscapes
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| EPPCT/EP2009/000834 | 2009-02-06 | ||
| PCT/EP2010/000722 WO2010089128A2 (en) | 2009-02-06 | 2010-02-05 | Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration |
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| CA2741052A1 CA2741052A1 (en) | 2010-08-12 |
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| CN101304748A (zh) | 2005-08-22 | 2008-11-12 | 加利福尼亚大学董事会 | Tlr激动剂 |
| EP2700638A1 (en) * | 2006-05-31 | 2014-02-26 | The Regents Of the University of California | Purine analogs |
| HUE025555T2 (en) | 2007-02-07 | 2016-02-29 | Univ California | Conjugates and applications of synthetic tlr agonists |
| US20100160368A1 (en) | 2008-08-18 | 2010-06-24 | Gregory Jefferson J | Methods of Treating Dermatological Disorders and Inducing Interferon Biosynthesis With Shorter Durations of Imiquimod Therapy |
| DK2378876T3 (en) | 2008-12-19 | 2019-03-11 | Medicis Pharmaceutical Corp | IMIQUIMOD FORMULATIONS WITH LOWER DOSAGE STRENGTH AND SHORT-TERM DOSAGE PLAN FOR TREATMENT OF ACTINIC KERATOSIS |
| WO2010088924A1 (en) | 2009-02-06 | 2010-08-12 | Telormedix Sa | Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration |
| EP2396328A2 (en) * | 2009-02-11 | 2011-12-21 | The Regents of The University of California | Toll-like receptor modulators and treatment of diseases |
| GEP20156418B (en) | 2009-07-13 | 2016-01-11 | Medicis Pharmaceutical Corp | Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts |
| GB201020193D0 (en) * | 2010-11-29 | 2011-01-12 | Biotec Pharmacon Asa | Glucan compositions |
| AU2012358803C1 (en) | 2011-12-22 | 2019-12-19 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| US9441007B2 (en) | 2012-03-21 | 2016-09-13 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| USRE48171E1 (en) | 2012-03-21 | 2020-08-25 | Janssen Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| MX2014014323A (es) | 2012-05-25 | 2015-02-12 | Janssen R & D Ireland | Nucleosidos de espirooxetano de uracilo. |
| JP6284547B2 (ja) | 2012-12-21 | 2018-02-28 | アリオス バイオファーマ インク． | 置換ヌクレオシド、置換ヌクレオチドおよびそれらの類似体 |
| EP3055319A4 (en) | 2013-10-11 | 2018-01-10 | Alios Biopharma, Inc. | Substituted nucleosides, nucleotides and analogs thereof |
| EP3659603A1 (en) * | 2014-01-10 | 2020-06-03 | Urogen Pharma Ltd. | Pharmaceutical compositions comprising imiquimod for use in the treatment of carcinoma in situ of the bladder |
| WO2015104030A1 (en) * | 2014-01-10 | 2015-07-16 | Telormedix Sa | Pharmaceutical compositions comprising imiquimod for use in the treatment of carcinoma in situ of the bladder |
| CN103751779A (zh) * | 2014-02-25 | 2014-04-30 | 中国农业科学院上海兽医研究所 | O型口蹄疫多肽的泊洛沙姆凝胶佐剂 |
| WO2017004421A1 (en) * | 2015-06-30 | 2017-01-05 | The Trustees Of The University Of Pennsylvania | Resiquimod topical and injectable compositions for the treatment of neoplastic skin conditions |
| CA2936070C (en) * | 2015-07-14 | 2023-07-04 | Professional Compounding Centers Of America (Pcca) | Poloxamer-based intralesional injections for the delivery of chemotherapeutic agents |
| US10533007B2 (en) | 2016-04-19 | 2020-01-14 | Innate Tumor Immunity, Inc. | NLRP3 modulators |
| MX2018012249A (es) | 2016-04-19 | 2019-02-07 | Innate Tumor Immunity Inc | Moduladores de nlpr3. |
| US11697851B2 (en) | 2016-05-24 | 2023-07-11 | The Regents Of The University Of California | Early ovarian cancer detection diagnostic test based on mRNA isoforms |
| US10858483B2 (en) | 2016-07-06 | 2020-12-08 | University Of Maryland, College Park | Polyphosphazene polyelectrolytes and uses thereof |
| TWI674261B (zh) | 2017-02-17 | 2019-10-11 | 美商英能腫瘤免疫股份有限公司 | Nlrp3 調節劑 |
| US20200087625A1 (en) * | 2017-03-30 | 2020-03-19 | Dennis A. Carson | Methods for isolating, expanding and administering cancer specific cd8+ t cells |
| BR112019020853A2 (pt) | 2017-04-04 | 2020-05-12 | Avidea Technologies, Inc. | Vacinas à base de peptídeo, métodos de fabricação e usos das mesmas para induzir uma resposta imune |
| CN107556310B (zh) * | 2017-09-20 | 2019-10-22 | 石家庄诚志永华显示材料有限公司 | 咪唑衍生物、包含该咪唑衍生物的材料和有机电致发光器件 |
| EA037780B1 (ru) * | 2017-10-18 | 2021-05-20 | Иннэйт Тьюмор Иммунити, Инк. | Модуляторы nlrp3 |
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