CA2737025C - Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof - Google Patents
Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof Download PDFInfo
- Publication number
- CA2737025C CA2737025C CA2737025A CA2737025A CA2737025C CA 2737025 C CA2737025 C CA 2737025C CA 2737025 A CA2737025 A CA 2737025A CA 2737025 A CA2737025 A CA 2737025A CA 2737025 C CA2737025 C CA 2737025C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- oil
- cholesterol
- acid
- finasteride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10071408P | 2008-09-27 | 2008-09-27 | |
| US61/100,714 | 2008-09-27 | ||
| PCT/US2009/058463 WO2010036947A2 (en) | 2008-09-27 | 2009-09-25 | Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2737025A1 CA2737025A1 (en) | 2010-04-01 |
| CA2737025C true CA2737025C (en) | 2012-09-04 |
Family
ID=42060413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2737025A Active CA2737025C (en) | 2008-09-27 | 2009-09-25 | Lipid based pharmaceutical preparations for oral and topical application; their compositions, methods, and uses thereof |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9750812B2 (https=) |
| EP (1) | EP2344198B1 (https=) |
| JP (3) | JP2012504135A (https=) |
| CA (1) | CA2737025C (https=) |
| CY (1) | CY1123579T1 (https=) |
| DK (1) | DK2344198T3 (https=) |
| ES (1) | ES2834006T3 (https=) |
| HR (1) | HRP20201860T1 (https=) |
| HU (1) | HUE052571T2 (https=) |
| LT (1) | LT2344198T (https=) |
| MX (1) | MX2011003207A (https=) |
| PL (1) | PL2344198T3 (https=) |
| PT (1) | PT2344198T (https=) |
| SI (1) | SI2344198T1 (https=) |
| WO (1) | WO2010036947A2 (https=) |
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| KR20180038574A (ko) | 2008-07-18 | 2018-04-16 | 바이오모드 컨셉츠 인코포레이티드 | 활성 성분을 방출하는 제품 |
| US10633688B2 (en) | 2010-09-24 | 2020-04-28 | Follea International | Systems and methods for predicting response to minoxidil for the treatment of androgenetic alopecia |
| US9588118B2 (en) | 2010-09-24 | 2017-03-07 | Follea International | Devices for performing colorimetric assay with plucked human hair |
| US8691518B2 (en) * | 2010-09-24 | 2014-04-08 | Global Life Science Partners Limited | Systems and methods for predicting response to minoxidil for the treatment of androgenetic alopecia |
| ITMI20102165A1 (it) * | 2010-11-23 | 2012-05-24 | Medichem Srl | Composizione per il lavaggio dei capelli e del cuoio capelluto |
| CN103596550A (zh) * | 2011-04-25 | 2014-02-19 | 朴俊炯 | 用于预防脱发和促进毛发生长的局部施用的组合物 |
| CN104394850A (zh) * | 2012-02-16 | 2015-03-04 | 布莱特赛德创新有限公司 | 膳食和营养组合物及应用的方法 |
| EP2844265A4 (en) * | 2012-04-25 | 2016-01-06 | Hadasit Med Res Service | POMEGRANATE OIL FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES |
| BR102012022036B1 (pt) | 2012-08-31 | 2019-10-01 | Biolab Sanus Farmacêutica Ltda. | Nanopartícula polimérica de finasterida e minoxidil, processo de sua preparação, suspensão aquosa contendo a mesma, composição farmacêutica, e seu uso |
| BR102012022034B1 (pt) | 2012-08-31 | 2020-02-18 | Biolab Sanus Farmacêutica Ltda. | Nanopartícula polimérica de finasterida, suspensão aquosa contendo a mesma, composição para tratamento de alopecia, processo de preparação de dita composição, e seu uso |
| US20150313829A1 (en) * | 2012-11-26 | 2015-11-05 | Roberto Queiroga Lautner | Topical formulations for the prevention and treatment of alopecia and inhibition of hair growth |
| JP6595454B2 (ja) * | 2013-05-03 | 2019-10-23 | リピドール エービー | 薬学的又は化粧学的活性成分を投与するための局部用組成物及びキャリアー |
| WO2015023926A1 (en) | 2013-08-15 | 2015-02-19 | Mary Kay Inc. | Topical skin compositions for treating wrinkles |
| US20150147382A1 (en) * | 2013-09-23 | 2015-05-28 | Exir Nano Sina Company | Topical liposomal compositions for delivering hydrophobic drugs and methods preparing same |
| US11660344B2 (en) | 2013-11-17 | 2023-05-30 | Medrx Co., Ltd. | Transdermal colloidal solution agent |
| WO2015072564A1 (ja) * | 2013-11-17 | 2015-05-21 | 株式会社メドレックス | 経皮吸収型コロイド液剤 |
| CN115998740A (zh) | 2014-10-29 | 2023-04-25 | 萨姆森临床私人有限公司 | 毛发过度脱落的检测和治疗 |
| ES2765277T3 (es) | 2014-12-22 | 2020-06-08 | Reactive Reality Gmbh | Método y sistema para generar datos de modelo de prenda |
| KR20180016347A (ko) * | 2015-04-13 | 2018-02-14 | 파운테인 테크놀로지스 인터내셔널, 엘엘씨 | 초-소형 지질 구조체의 생산을 위한 단일-단계 방법 |
| CN107613961B (zh) * | 2015-05-19 | 2021-07-13 | 美德阿利克斯株式会社 | 经皮吸收型液体制剂 |
| SG11201809154UA (en) | 2016-04-19 | 2018-11-29 | Univ Nanyang Tech | Nanoliposomes for sustained delivery of tacrolimus for treatment of anterior segment eye diseases |
| MD3532067T2 (ro) | 2016-10-28 | 2022-10-31 | Servier Lab | Formă farmaceutică lipozomală pentru utilizare în tratamentul cancerului |
| CA3063954A1 (en) * | 2017-05-30 | 2018-12-06 | Glaxosmithline Biologicals S.A. | Methods for manufacturing an adjuvant |
| EP3630076A1 (en) | 2017-05-30 | 2020-04-08 | GlaxoSmithKline Biologicals SA | Methods for manufacturing a liposome encapsulated rna |
| AU2018250398B2 (en) * | 2017-07-12 | 2019-02-28 | Samson Clinical Pty Ltd | Promoting hair growth and treatment of hair loss or excessive hair shedding |
| CA3080205A1 (en) * | 2017-10-27 | 2019-05-02 | TopiRX Therapeutics Inc. | Topical formulations for treating dermatological disorders including male pattern baldness |
| MX390288B (es) | 2018-02-06 | 2025-03-20 | Centro Int De Cosmiatria S A P I De C V | Formulación y método para el tratamiento de la alopecia androgénica. |
| WO2020097284A1 (en) * | 2018-11-08 | 2020-05-14 | Jindal Vinay K | TOPICAL FORMULATIONS OF 5-α-REDUCTASE INHIBITORS AND USES THEREOF |
| WO2020109365A1 (en) | 2018-11-29 | 2020-06-04 | Glaxosmithkline Biologicals Sa | Methods for manufacturing an adjuvant |
| US12533318B2 (en) | 2019-08-30 | 2026-01-27 | Glaxosmithkline Biologicals Sa | Jet mixing lipid nanoparticle manufacturing process |
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| US11311556B2 (en) | 2020-05-13 | 2022-04-26 | Varsona Therapeutics, Inc. | Topical dutasteride emulsions for treating endocrine therapy-induced alopecia |
| US11850300B2 (en) | 2022-03-17 | 2023-12-26 | Rally Guide | Topical lotion composition, methods of use, and methods of preparation |
| WO2024213098A1 (zh) * | 2023-04-14 | 2024-10-17 | 北京剂泰医药科技有限公司 | 靶向脾的脂质纳米颗粒 |
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| JP2006290841A (ja) * | 2005-04-14 | 2006-10-26 | Nippon Zettoc Co Ltd | 化粧料の製造方法および化粧料 |
| DE102005026755A1 (de) * | 2005-06-09 | 2006-12-14 | Basf Ag | Herstellung von festen Lösungen schwerlöslicher Wirkstoffe durch Kurzzeitüberhitzung und schnelle Trocknung |
| EP2029106A2 (en) * | 2006-06-07 | 2009-03-04 | Foamix Ltd. | Foamable vehicle comprising polypropylene glycol alkyl ether and pharmaceutical compositions thereof |
| JP5917789B2 (ja) * | 2006-10-10 | 2016-05-18 | ジャイナ ファーマシューティカルズ,インコーポレーテッド | 脂質ベースの医薬化合物の製造のための水性系、その組成物、方法、および使用 |
| GB0623838D0 (en) * | 2006-11-29 | 2007-01-10 | Malvern Cosmeceutics Ltd | Novel compositions |
| CN101559038B (zh) | 2009-05-21 | 2011-03-16 | 江苏黄河药业股份有限公司 | 非那雄胺的固体脂质纳米粒及其制备方法 |
-
2009
- 2009-09-25 LT LTEP09816940.2T patent/LT2344198T/lt unknown
- 2009-09-25 HR HRP20201860TT patent/HRP20201860T1/hr unknown
- 2009-09-25 JP JP2011529277A patent/JP2012504135A/ja active Pending
- 2009-09-25 SI SI200932098T patent/SI2344198T1/sl unknown
- 2009-09-25 EP EP09816940.2A patent/EP2344198B1/en active Active
- 2009-09-25 PT PT98169402T patent/PT2344198T/pt unknown
- 2009-09-25 DK DK09816940.2T patent/DK2344198T3/da active
- 2009-09-25 HU HUE09816940A patent/HUE052571T2/hu unknown
- 2009-09-25 WO PCT/US2009/058463 patent/WO2010036947A2/en not_active Ceased
- 2009-09-25 MX MX2011003207A patent/MX2011003207A/es active IP Right Grant
- 2009-09-25 US US13/120,127 patent/US9750812B2/en active Active
- 2009-09-25 PL PL09816940T patent/PL2344198T3/pl unknown
- 2009-09-25 ES ES09816940T patent/ES2834006T3/es active Active
- 2009-09-25 CA CA2737025A patent/CA2737025C/en active Active
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2014
- 2014-06-25 JP JP2014130194A patent/JP6196943B2/ja active Active
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- 2016-09-09 JP JP2016176561A patent/JP2017048188A/ja active Pending
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- 2020-11-26 CY CY20201101126T patent/CY1123579T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUE052571T2 (hu) | 2021-05-28 |
| DK2344198T3 (da) | 2020-11-30 |
| JP2014221784A (ja) | 2014-11-27 |
| SI2344198T1 (sl) | 2021-01-29 |
| PT2344198T (pt) | 2020-12-04 |
| LT2344198T (lt) | 2021-02-25 |
| HRP20201860T1 (hr) | 2021-04-16 |
| CA2737025A1 (en) | 2010-04-01 |
| JP6196943B2 (ja) | 2017-09-13 |
| EP2344198A4 (en) | 2013-01-09 |
| PL2344198T3 (pl) | 2021-05-31 |
| CY1123579T1 (el) | 2022-03-24 |
| EP2344198A2 (en) | 2011-07-20 |
| WO2010036947A2 (en) | 2010-04-01 |
| MX2011003207A (es) | 2011-11-04 |
| US9750812B2 (en) | 2017-09-05 |
| ES2834006T3 (es) | 2021-06-16 |
| WO2010036947A3 (en) | 2010-06-10 |
| JP2012504135A (ja) | 2012-02-16 |
| EP2344198B1 (en) | 2020-11-04 |
| US20110212167A1 (en) | 2011-09-01 |
| JP2017048188A (ja) | 2017-03-09 |
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