ATE440593T1 - Verfahren und zusammensetzung zur solubilisierung einer biologisch wirksamen verbindung mit geringer wasserlíslichkeit - Google Patents

Verfahren und zusammensetzung zur solubilisierung einer biologisch wirksamen verbindung mit geringer wasserlíslichkeit

Info

Publication number
ATE440593T1
ATE440593T1 AT02737899T AT02737899T ATE440593T1 AT E440593 T1 ATE440593 T1 AT E440593T1 AT 02737899 T AT02737899 T AT 02737899T AT 02737899 T AT02737899 T AT 02737899T AT E440593 T1 ATE440593 T1 AT E440593T1
Authority
AT
Austria
Prior art keywords
biologically active
lipid particles
container
lipophilic
solubilizing
Prior art date
Application number
AT02737899T
Other languages
English (en)
Inventor
Steve Leigh
Mathew Louis Steven Leigh
Hoogevest Peter Van
Henricus Tiemessen
Original Assignee
Phares Pharm Res Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phares Pharm Res Nv filed Critical Phares Pharm Res Nv
Application granted granted Critical
Publication of ATE440593T1 publication Critical patent/ATE440593T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT02737899T 2001-03-27 2002-03-26 Verfahren und zusammensetzung zur solubilisierung einer biologisch wirksamen verbindung mit geringer wasserlíslichkeit ATE440593T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01302841 2001-03-27
PCT/EP2002/003371 WO2002080883A2 (en) 2001-03-27 2002-03-26 Method and composition for solubilising a biologically active compound with low water solubility

Publications (1)

Publication Number Publication Date
ATE440593T1 true ATE440593T1 (de) 2009-09-15

Family

ID=8181836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02737899T ATE440593T1 (de) 2001-03-27 2002-03-26 Verfahren und zusammensetzung zur solubilisierung einer biologisch wirksamen verbindung mit geringer wasserlíslichkeit

Country Status (11)

Country Link
US (2) US20040115255A1 (de)
EP (1) EP1389089B1 (de)
JP (3) JP2004524368A (de)
AT (1) ATE440593T1 (de)
AU (1) AU2002312777B2 (de)
CA (1) CA2442539C (de)
DE (1) DE60233484D1 (de)
DK (1) DK1389089T3 (de)
ES (1) ES2332584T3 (de)
PT (1) PT1389089E (de)
WO (1) WO2002080883A2 (de)

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Also Published As

Publication number Publication date
US20040115255A1 (en) 2004-06-17
DK1389089T3 (da) 2009-12-21
WO2002080883A2 (en) 2002-10-17
CA2442539A1 (en) 2002-10-17
PT1389089E (pt) 2009-11-30
CA2442539C (en) 2011-11-08
WO2002080883A3 (en) 2003-12-11
JP2004524368A (ja) 2004-08-12
JP2012207042A (ja) 2012-10-25
AU2002312777B2 (en) 2007-07-05
ES2332584T3 (es) 2010-02-09
AU2002312777A2 (en) 2002-10-21
US20080131499A1 (en) 2008-06-05
EP1389089B1 (de) 2009-08-26
JP2010013461A (ja) 2010-01-21
DE60233484D1 (de) 2009-10-08
EP1389089A2 (de) 2004-02-18

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