CA2377024A1 - Ophthalmic composition comprising ketotifen - Google Patents

Ophthalmic composition comprising ketotifen Download PDF

Info

Publication number
CA2377024A1
CA2377024A1 CA002377024A CA2377024A CA2377024A1 CA 2377024 A1 CA2377024 A1 CA 2377024A1 CA 002377024 A CA002377024 A CA 002377024A CA 2377024 A CA2377024 A CA 2377024A CA 2377024 A1 CA2377024 A1 CA 2377024A1
Authority
CA
Canada
Prior art keywords
composition
ketotifen
glycerol
preservative
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002377024A
Other languages
English (en)
French (fr)
Inventor
Marcia Johanna Adam
Andrea Fetz
Gyorgy Lajos Kis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2377024A1 publication Critical patent/CA2377024A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA002377024A 1999-07-23 2000-07-21 Ophthalmic composition comprising ketotifen Abandoned CA2377024A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99114508 1999-07-23
EP99114508.7 1999-07-23
PCT/EP2000/007030 WO2001007049A2 (en) 1999-07-23 2000-07-21 Ophthalmic composition comprising ketotifen

Publications (1)

Publication Number Publication Date
CA2377024A1 true CA2377024A1 (en) 2001-02-01

Family

ID=8238654

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002377024A Abandoned CA2377024A1 (en) 1999-07-23 2000-07-21 Ophthalmic composition comprising ketotifen

Country Status (20)

Country Link
US (2) US6777429B1 (pt)
EP (1) EP1198223A2 (pt)
JP (1) JP2003505419A (pt)
KR (1) KR20020012261A (pt)
CN (1) CN1358086A (pt)
BR (2) BR0012696A (pt)
CA (1) CA2377024A1 (pt)
CZ (1) CZ300614B6 (pt)
EE (1) EE05439B1 (pt)
HK (1) HK1046631A1 (pt)
HU (1) HU230738B1 (pt)
IL (1) IL146973A0 (pt)
MX (1) MXPA02000849A (pt)
NO (1) NO331228B1 (pt)
NZ (1) NZ516108A (pt)
PL (1) PL202496B1 (pt)
RU (1) RU2248789C2 (pt)
UA (1) UA74788C2 (pt)
WO (1) WO2001007049A2 (pt)
ZA (1) ZA200200425B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002345015A1 (en) * 2001-06-08 2002-12-23 Novartis Pharma Gmbh Ophthalmic once-a-day composition
AR034371A1 (es) * 2001-06-08 2004-02-18 Novartis Ag Composiciones farmaceuticas
AR034372A1 (es) * 2001-06-08 2004-02-18 Novartis Ag Composiciones farmaceuticas
CN1738610A (zh) * 2003-01-22 2006-02-22 日绊株式会社 眼疾治疗用经皮吸收型制剂、其使用及眼疾治疗药向眼局部组织的转移方法
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
US20060089384A1 (en) * 2004-10-25 2006-04-27 Minno George E Ophthalmic compositions and methods of using the same
ATE463244T1 (de) * 2004-10-25 2010-04-15 Bausch & Lomb Ophthalmische zusammensetzungen und verfahren zu deren verwendung
US20070048389A1 (en) * 2005-08-26 2007-03-01 Fu-Pao Tsao Stabilized and preserved ketotifen ophthalmic compositions
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
CA2654510C (en) 2006-06-16 2015-03-17 Regeneron Pharmaceuticals, Inc. Vegf antagonist formulations suitable for intravitreal administration
US8445437B2 (en) * 2006-07-27 2013-05-21 The Brigham And Women's Hospital, Inc. Treatment and prevention of cardiovascular disease using mast cell stabilizers
HUE033597T2 (hu) 2006-09-29 2017-12-28 Johnson & Johnson Vision Care Eljárás allergia elleni szert tartalmazó szemészeti eszköz oxidációjának megelõzésére
US20100166804A1 (en) * 2007-05-23 2010-07-01 Dennis Penn Methods
EP2205243A4 (en) 2007-09-28 2012-06-13 Brigham & Womens Hospital STABILIZERS OF MAST CELLS IN THE TREATMENT OF OBESITY
WO2009142772A2 (en) * 2008-05-23 2009-11-26 Mastcell Pharmaceuticals, Inc. Methods and treatment for allergies and inflammation associated with gastrointestinal diseases
CA2754996A1 (en) * 2009-03-17 2010-09-23 Aciex Therapeutics, Inc. Ophthalmic formulations of ketotifen and methods of use
RU2549472C1 (ru) * 2013-12-26 2015-04-27 Илья Александрович Марков Фармацевтическая композиция в форме капель для профилактики и лечения аллергических заболеваний глаз
IL302424A (en) 2015-12-03 2023-06-01 Regeneron Pharma Methods for associating genetic variants with clinical outcome in patients suffering from age-related macular degeneration and receiving treatment against tubular endothelial growth factor
CN111450051B (zh) * 2020-04-21 2022-03-18 武汉贝参药业股份有限公司 一种富马酸酮替芬口服溶液的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62277323A (ja) 1986-02-19 1987-12-02 Sankyo Co Ltd フマル酸ケトチフエン含有点眼液の製法
JPH07324034A (ja) * 1994-05-30 1995-12-12 Toa Yakuhin Kk フマル酸ケトチフェン含有の点眼剤
JPH11189533A (ja) * 1997-12-25 1999-07-13 Taisho Pharmaceut Co Ltd 点眼薬
EP0938896A1 (en) 1998-01-15 1999-09-01 Novartis AG Autoclavable pharmaceutical compositions containing a chelating agent

Also Published As

Publication number Publication date
WO2001007049A2 (en) 2001-02-01
US6774137B2 (en) 2004-08-10
CZ2002243A3 (cs) 2002-04-17
UA74788C2 (en) 2006-02-15
CZ300614B6 (cs) 2009-07-01
KR20020012261A (ko) 2002-02-15
RU2248789C2 (ru) 2005-03-27
EE05439B1 (et) 2011-08-15
US6777429B1 (en) 2004-08-17
US20020183359A1 (en) 2002-12-05
HU230738B1 (hu) 2018-01-29
HUP0202243A2 (hu) 2002-12-28
CN1358086A (zh) 2002-07-10
NZ516108A (en) 2004-04-30
WO2001007049A3 (en) 2001-03-29
PL202496B1 (pl) 2009-06-30
EE200200040A (et) 2003-04-15
BRPI0017528B1 (pt) 2017-06-13
ZA200200425B (en) 2002-10-30
NO331228B1 (no) 2011-11-07
HUP0202243A3 (en) 2006-03-28
BR0012696A (pt) 2002-04-09
IL146973A0 (en) 2002-08-14
NO20020319L (no) 2002-01-21
JP2003505419A (ja) 2003-02-12
NO20020319D0 (no) 2002-01-21
HK1046631A1 (zh) 2003-01-24
BRPI0017528B8 (pt) 2021-05-25
BRPI0017528A2 (pt) 2010-01-19
PL352382A1 (en) 2003-08-25
EP1198223A2 (en) 2002-04-24
MXPA02000849A (es) 2002-07-30

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued