HUP0202243A2 - Ketotiféntartalmú szemészeti készítmény - Google Patents

Ketotiféntartalmú szemészeti készítmény

Info

Publication number
HUP0202243A2
HUP0202243A2 HU0202243A HUP0202243A HUP0202243A2 HU P0202243 A2 HUP0202243 A2 HU P0202243A2 HU 0202243 A HU0202243 A HU 0202243A HU P0202243 A HUP0202243 A HU P0202243A HU P0202243 A2 HUP0202243 A2 HU P0202243A2
Authority
HU
Hungary
Prior art keywords
preservative
ketotifen
salt
preparation
named
Prior art date
Application number
HU0202243A
Other languages
English (en)
Inventor
Marcia Johanna Adam
Andrea Fetz
György Lajos Kis
Original Assignee
Novartis Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag. filed Critical Novartis Ag.
Publication of HUP0202243A2 publication Critical patent/HUP0202243A2/hu
Publication of HUP0202243A3 publication Critical patent/HUP0202243A3/hu
Publication of HU230738B1 publication Critical patent/HU230738B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Abstract

A találmány tárgya szemészeti gyógyszerkészítmény, mely egyketotifénsót, az összkészítménynek 210-290 milliozmól ozmótikusnyomást biztosító mennyiségű, nem ionos ágenst, adott esetbentartósítószert, gyengén savas kémhatást beállító savat vagy bázist ésvizet tartalmaz, és ahol a nevezett készítmény nem tartalmazstabilizálószert, továbbá (a) a nevezett tartósítószer hiányzik és aketotifénsó koncentrációja 0,01-0,04 tömeg%; vagy (b) a nevezetttartósítószer jelen van és a ketotifénsó koncentrációja 0,01-0,03tömeg%. Ó
HU0202243A 1999-07-23 2000-07-21 Ketotifén tartalmú szemészeti készítmény HU230738B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99114508 1999-07-23
EP99114508.7 1999-07-23
PCT/EP2000/007030 WO2001007049A2 (en) 1999-07-23 2000-07-21 Ophthalmic composition comprising ketotifen

Publications (3)

Publication Number Publication Date
HUP0202243A2 true HUP0202243A2 (hu) 2002-12-28
HUP0202243A3 HUP0202243A3 (en) 2006-03-28
HU230738B1 HU230738B1 (hu) 2018-01-29

Family

ID=8238654

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202243A HU230738B1 (hu) 1999-07-23 2000-07-21 Ketotifén tartalmú szemészeti készítmény

Country Status (20)

Country Link
US (2) US6777429B1 (hu)
EP (1) EP1198223A2 (hu)
JP (1) JP2003505419A (hu)
KR (1) KR20020012261A (hu)
CN (1) CN1358086A (hu)
BR (2) BR0012696A (hu)
CA (1) CA2377024A1 (hu)
CZ (1) CZ300614B6 (hu)
EE (1) EE05439B1 (hu)
HK (1) HK1046631A1 (hu)
HU (1) HU230738B1 (hu)
IL (1) IL146973A0 (hu)
MX (1) MXPA02000849A (hu)
NO (1) NO331228B1 (hu)
NZ (1) NZ516108A (hu)
PL (1) PL202496B1 (hu)
RU (1) RU2248789C2 (hu)
UA (1) UA74788C2 (hu)
WO (1) WO2001007049A2 (hu)
ZA (1) ZA200200425B (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR034372A1 (es) * 2001-06-08 2004-02-18 Novartis Ag Composiciones farmaceuticas
AR034371A1 (es) * 2001-06-08 2004-02-18 Novartis Ag Composiciones farmaceuticas
WO2002100436A2 (en) * 2001-06-08 2002-12-19 Novartis Ag Ophthalmic once-a-day composition
KR20050092429A (ko) * 2003-01-22 2005-09-21 니찌방 가부시기가이샤 안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환치료약의 눈의 국소 조직으로의 이행 방법
US20060089384A1 (en) * 2004-10-25 2006-04-27 Minno George E Ophthalmic compositions and methods of using the same
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
CA2585266C (en) * 2004-10-25 2010-10-19 Bausch & Lomb Incorporated Ophthalmic compositions and methods of using the same
US20070048389A1 (en) * 2005-08-26 2007-03-01 Fu-Pao Tsao Stabilized and preserved ketotifen ophthalmic compositions
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
EP2029103A2 (en) 2006-06-16 2009-03-04 Regeneron Pharmaceuticals, Inc. Vegf antagonist formulations suitable for intravitreal administration
US8445437B2 (en) * 2006-07-27 2013-05-21 The Brigham And Women's Hospital, Inc. Treatment and prevention of cardiovascular disease using mast cell stabilizers
SG177934A1 (en) 2006-09-29 2012-02-28 Johnson & Johnson Vision Care Methods and ophthalmic devices used in the treatment of ocular allergies
WO2008153761A1 (en) * 2007-05-23 2008-12-18 Mastcell Pharmaceuticals, Inc. Methods
US8445435B2 (en) * 2007-09-28 2013-05-21 The Brigham And Women's Hospital, Inc. Mast cell stabilizers in the treatment of obesity
WO2009142772A2 (en) 2008-05-23 2009-11-26 Mastcell Pharmaceuticals, Inc. Methods and treatment for allergies and inflammation associated with gastrointestinal diseases
JP2012520880A (ja) * 2009-03-17 2012-09-10 アーシエックス セラピューティックス， インコーポレイテッド ケトチフェンの眼科用製剤および使用方法
RU2549472C1 (ru) * 2013-12-26 2015-04-27 Илья Александрович Марков Фармацевтическая композиция в форме капель для профилактики и лечения аллергических заболеваний глаз
AU2016364817B2 (en) 2015-12-03 2020-05-07 Regeneron Pharmaceuticals, Inc. Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF
CN111450051B (zh) * 2020-04-21 2022-03-18 武汉贝参药业股份有限公司 一种富马酸酮替芬口服溶液的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62277323A (ja) 1986-02-19 1987-12-02 Sankyo Co Ltd フマル酸ケトチフエン含有点眼液の製法
JPH07324034A (ja) * 1994-05-30 1995-12-12 Toa Yakuhin Kk フマル酸ケトチフェン含有の点眼剤
JPH11189533A (ja) * 1997-12-25 1999-07-13 Taisho Pharmaceut Co Ltd 点眼薬
EP0938896A1 (en) 1998-01-15 1999-09-01 Novartis AG Autoclavable pharmaceutical compositions containing a chelating agent

Also Published As

Publication number Publication date
NO331228B1 (no) 2011-11-07
US6777429B1 (en) 2004-08-17
EP1198223A2 (en) 2002-04-24
EE05439B1 (et) 2011-08-15
EE200200040A (et) 2003-04-15
IL146973A0 (en) 2002-08-14
CA2377024A1 (en) 2001-02-01
US6774137B2 (en) 2004-08-10
BR0012696A (pt) 2002-04-09
RU2248789C2 (ru) 2005-03-27
NO20020319D0 (no) 2002-01-21
NZ516108A (en) 2004-04-30
BRPI0017528A2 (pt) 2010-01-19
BRPI0017528B8 (pt) 2021-05-25
CN1358086A (zh) 2002-07-10
HK1046631A1 (zh) 2003-01-24
HU230738B1 (hu) 2018-01-29
US20020183359A1 (en) 2002-12-05
MXPA02000849A (es) 2002-07-30
PL352382A1 (en) 2003-08-25
ZA200200425B (en) 2002-10-30
KR20020012261A (ko) 2002-02-15
BRPI0017528B1 (pt) 2017-06-13
PL202496B1 (pl) 2009-06-30
WO2001007049A2 (en) 2001-02-01
WO2001007049A3 (en) 2001-03-29
CZ300614B6 (cs) 2009-07-01
HUP0202243A3 (en) 2006-03-28
CZ2002243A3 (cs) 2002-04-17
NO20020319L (no) 2002-01-21
UA74788C2 (en) 2006-02-15
JP2003505419A (ja) 2003-02-12

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