TW200628468A - Bicyclononene derivatives - Google Patents

Bicyclononene derivatives

Info

Publication number
TW200628468A
TW200628468A TW094128948A TW94128948A TW200628468A TW 200628468 A TW200628468 A TW 200628468A TW 094128948 A TW094128948 A TW 094128948A TW 94128948 A TW94128948 A TW 94128948A TW 200628468 A TW200628468 A TW 200628468A
Authority
TW
Taiwan
Prior art keywords
bicyclononene
derivatives
preparation
pharmaceutical compositions
bicyclononene derivatives
Prior art date
Application number
TW094128948A
Other languages
Chinese (zh)
Inventor
Olivier Bezencon
Christoph Boss
Daniel Bur
Olivier Corminboeuf
Walter Fischli
Corinna Grisostomi
Lubos Remen
Sylvia Richard-Bildstein
Thierry Sifferlen
Thomas Weller
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of TW200628468A publication Critical patent/TW200628468A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

The invention relates to bicyclononene derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
TW094128948A 2004-08-25 2005-08-24 Bicyclononene derivatives TW200628468A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP2004009476 2004-08-25

Publications (1)

Publication Number Publication Date
TW200628468A true TW200628468A (en) 2006-08-16

Family

ID=35395835

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094128948A TW200628468A (en) 2004-08-25 2005-08-24 Bicyclononene derivatives

Country Status (3)

Country Link
AR (1) AR052769A1 (en)
TW (1) TW200628468A (en)
WO (1) WO2006021401A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8129538B1 (en) 2007-03-28 2012-03-06 Takeda Pharmaceutical Company Limited Renin inhibitors
US8343968B2 (en) 2007-05-24 2013-01-01 Merck Canada Inc. Case of renin inhibitors
US8334308B2 (en) 2007-08-20 2012-12-18 Merck Sharp & Dohme Corp. Renin inhibitors
MX2010012067A (en) 2008-05-05 2010-12-06 Merck Frosst Canada Ltd 3, 4 - substituted piperidine derivatives as renin inhibitors.
CN102112440A (en) 2008-05-30 2011-06-29 武田药品工业株式会社 Heterocyclic compound
JP5809157B2 (en) 2010-10-08 2015-11-10 持田製薬株式会社 Cyclic amide derivative
US9072758B2 (en) 2011-04-28 2015-07-07 Mochida Pharmaceutical Co., Ltd. Cyclic amide derivative
CN115819186B (en) * 2023-02-14 2023-05-16 广东银珠医药科技有限公司 Novel preparation method of 3, 5-dichlorobenzyl alcohol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL372141A1 (en) * 2002-04-29 2005-07-11 Actelion Pharmaceuticals Ltd. 7-aryl-3,9-diazabicyclo[3.3.1]non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases

Also Published As

Publication number Publication date
AR052769A1 (en) 2007-04-04
WO2006021401A3 (en) 2006-04-13
WO2006021401A2 (en) 2006-03-02

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