HUP0204202A2 - Ibuprofent tartalmazó hatóanyag-preparátum, eljárás az előállítására és ezt tartalmazó gyógyszerkészítmények - Google Patents

Ibuprofent tartalmazó hatóanyag-preparátum, eljárás az előállítására és ezt tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0204202A2
HUP0204202A2 HU0204202A HUP0204202A HUP0204202A2 HU P0204202 A2 HUP0204202 A2 HU P0204202A2 HU 0204202 A HU0204202 A HU 0204202A HU P0204202 A HUP0204202 A HU P0204202A HU P0204202 A2 HUP0204202 A2 HU P0204202A2
Authority
HU
Hungary
Prior art keywords
ibuprofen
preparation
pharmaceutical compositions
active agent
cellulose
Prior art date
Application number
HU0204202A
Other languages
English (en)
Inventor
Heinz Einig
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of HUP0204202A2 publication Critical patent/HUP0204202A2/hu
Publication of HUP0204202A3 publication Critical patent/HUP0204202A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgyát ibuprofent tartalmazó hatóanyag-preparátumok,eljárás az előállításukra - amelyet az jellemez, hogy az ibuprofentvagy a sóit (hidroxi-metil)-propil-cellulózzal, metil-cellulózzal,nátrium-(karboxi-metil)-cellulózzal, (hidroxi-propil)-cellulózzal vagyzselatinnal mint kötőanyaggal vonják be, ahol a hatóanyag-preparátumszáraztömegére vonatkoztatva a kötőanyag koncentrációja 0,1-10 tömeg%,és az ibuprofennek vagy a sóinak a koncentrációja pedig 90-99,9 tömeg%- és alkalmazásuk gyógyszerkészítmények és szilárd gyógyszerformákelőállítására, valamint az ibuprofen-hatóanyag-preparátumot tartalmazógyógyszerkészítmények és szilárd gyógyszerformák képezik. Ó
HU0204202A 2000-01-28 2001-01-19 Ibuprofen containing active agent preparation, process for its preparation and pharmaceutical compositions containing it HUP0204202A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10003757A DE10003757A1 (de) 2000-01-28 2000-01-28 Ibuprofen-Wirkstoffzubereitung
PCT/EP2001/000602 WO2001054683A1 (de) 2000-01-28 2001-01-19 Ibuprofen-wirkstoffzubereitung

Publications (2)

Publication Number Publication Date
HUP0204202A2 true HUP0204202A2 (hu) 2003-03-28
HUP0204202A3 HUP0204202A3 (en) 2003-04-28

Family

ID=7629069

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0204202A HUP0204202A3 (en) 2000-01-28 2001-01-19 Ibuprofen containing active agent preparation, process for its preparation and pharmaceutical compositions containing it

Country Status (20)

Country Link
US (1) US20030045580A1 (hu)
EP (1) EP1250132B1 (hu)
JP (1) JP2003525223A (hu)
KR (1) KR100742489B1 (hu)
CN (1) CN1277535C (hu)
AT (1) ATE291908T1 (hu)
AU (1) AU784128B2 (hu)
BR (1) BR0107899A (hu)
CA (1) CA2398288A1 (hu)
CZ (1) CZ296485B6 (hu)
DE (2) DE10003757A1 (hu)
ES (1) ES2239119T3 (hu)
HU (1) HUP0204202A3 (hu)
IL (2) IL150528A0 (hu)
MX (1) MXPA02007076A (hu)
NO (1) NO20023551L (hu)
RU (1) RU2300368C2 (hu)
TW (1) TWI288641B (hu)
WO (1) WO2001054683A1 (hu)
ZA (1) ZA200206833B (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
JP5248733B2 (ja) * 2003-11-28 2013-07-31 エスエス製薬株式会社 揮散防止型固形製剤およびその製造方法
US20070077297A1 (en) * 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
US20060068009A1 (en) * 2004-09-30 2006-03-30 Scolr Pharma, Inc. Modified release ibuprofen dosage form
BRPI0503756A (pt) * 2005-09-06 2007-05-15 Gold Nutrition Pesquisa Desenv método de processamento de soja pelo uso de enzima especìfica, pó de soja processada e lìquido de soja processada
PL2043637T3 (pl) 2006-07-18 2012-06-29 Horizon Pharma Usa Inc Sposoby i leki do podawania ibuprofenu
US7749537B2 (en) 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
EP2133096A4 (en) * 2007-03-13 2011-11-16 Dainippon Sumitomo Pharma Co IN THE MOUTHING TABLET
CN101829064B (zh) * 2010-04-27 2012-04-25 海南新中正制药有限公司 右旋布洛芬颗粒及其制备方法
CN103002882B (zh) 2010-05-10 2016-03-02 欧洲凯尔特公司 不含活性剂之颗粒及包含其之片剂的制备
US9901540B2 (en) 2010-05-10 2018-02-27 Euro-Celtique S.A. Combination of active loaded granules with additional actives
JP2010189443A (ja) * 2010-06-07 2010-09-02 Ss Pharmaceut Co Ltd 揮散防止型固形製剤およびその製造方法
CN102988322B (zh) * 2012-12-26 2014-09-03 合肥科大生物技术有限公司 一种精氨酸布洛芬片剂及其制备方法
US9615595B2 (en) 2013-03-05 2017-04-11 Mera Technology International Inc. Method and apparatus for wasteless homogenized soybean beverage production
KR102194174B1 (ko) 2013-11-13 2020-12-23 유로-셀티큐 에스.에이. 통증 및 오피오이드 장 기능장애 증후군의 치료를 위한 히드로모르폰 및 날록손
WO2019072877A1 (en) * 2017-10-10 2019-04-18 Capsugel Belgium Nv GETTING MULTIPARTICULAR COMPOSITIONS
WO2022024066A1 (en) * 2020-07-31 2022-02-03 Catalent U.K. Swindon Zydis Limited Pharmaceutical compositions comprising coated api

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
US4980375A (en) * 1987-07-10 1990-12-25 Sterling Drug Inc. Onset-hastened/enhanced antipyretic response
US4911921A (en) * 1989-02-02 1990-03-27 Mallinckrodt, Inc. High ibuprofen content granulations
US4990535A (en) * 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
HUT59653A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alcanoic acids and alpha-hydroxy-alcanoic acids and pharmaceutical compositions containing them as active components
GB9119052D0 (en) * 1991-09-06 1991-10-23 Boots Co Plc Pharmaceutical compositions
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
US5646167A (en) * 1993-01-06 1997-07-08 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamix acids
IT1270239B (it) * 1994-06-17 1997-04-29 Zambon Spa Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo
US5534263A (en) * 1995-02-24 1996-07-09 Alza Corporation Active agent dosage form comprising a matrix and at least two insoluble bands
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
US5780055A (en) * 1996-09-06 1998-07-14 University Of Maryland, Baltimore Cushioning beads and tablet comprising the same capable of forming a suspension
US5904937A (en) * 1997-10-03 1999-05-18 Fmc Corporation Taste masked pharmaceutical compositions

Also Published As

Publication number Publication date
NO20023551D0 (no) 2002-07-25
HUP0204202A3 (en) 2003-04-28
IL150528A0 (en) 2003-02-12
CZ296485B6 (cs) 2006-03-15
DE50105771D1 (de) 2005-05-04
BR0107899A (pt) 2002-11-05
RU2002123182A (ru) 2004-03-20
ES2239119T3 (es) 2005-09-16
CA2398288A1 (en) 2001-08-02
MXPA02007076A (es) 2003-03-27
KR100742489B1 (ko) 2007-07-24
JP2003525223A (ja) 2003-08-26
DE10003757A1 (de) 2001-08-02
AU784128B2 (en) 2006-02-09
RU2300368C2 (ru) 2007-06-10
ZA200206833B (en) 2003-08-27
WO2001054683A1 (de) 2001-08-02
CZ20022605A3 (cs) 2003-02-12
CN1277535C (zh) 2006-10-04
AU3019701A (en) 2001-08-07
CN1400896A (zh) 2003-03-05
US20030045580A1 (en) 2003-03-06
TWI288641B (en) 2007-10-21
KR20020069368A (ko) 2002-08-30
NO20023551L (no) 2002-07-25
EP1250132A1 (de) 2002-10-23
IL150528A (en) 2007-06-17
EP1250132B1 (de) 2005-03-30
ATE291908T1 (de) 2005-04-15

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees