CA2374402A1 - Biosynthesis of foreign proteins using transformed microalgae - Google Patents

Biosynthesis of foreign proteins using transformed microalgae Download PDF

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Publication number
CA2374402A1
CA2374402A1 CA002374402A CA2374402A CA2374402A1 CA 2374402 A1 CA2374402 A1 CA 2374402A1 CA 002374402 A CA002374402 A CA 002374402A CA 2374402 A CA2374402 A CA 2374402A CA 2374402 A1 CA2374402 A1 CA 2374402A1
Authority
CA
Canada
Prior art keywords
microalgae
protein
gene
transformed
chlorella
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002374402A
Other languages
English (en)
French (fr)
Inventor
Tae-Jin Choi
Young-Tae Kim
Dae-Hyun Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALGENETECH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2374402A1 publication Critical patent/CA2374402A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01GHORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
    • A01G33/00Cultivation of seaweed or algae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Fodder In General (AREA)
CA002374402A 1999-05-28 2000-03-17 Biosynthesis of foreign proteins using transformed microalgae Abandoned CA2374402A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1019990019439A KR20000075076A (ko) 1999-05-28 1999-05-28 형질전환된 미세조류를 이용하여 외래 단백질을 생산하는 방법
KR1999/19439 1999-05-28
PCT/KR2000/000233 WO2000073455A1 (en) 1999-05-28 2000-03-17 Biosynthesis of foreign proteins using transformed microalgae

Publications (1)

Publication Number Publication Date
CA2374402A1 true CA2374402A1 (en) 2000-12-07

Family

ID=19588391

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002374402A Abandoned CA2374402A1 (en) 1999-05-28 2000-03-17 Biosynthesis of foreign proteins using transformed microalgae

Country Status (7)

Country Link
EP (1) EP1180145A1 (zh)
JP (1) JP2003501031A (zh)
KR (2) KR20000075076A (zh)
CN (1) CN1354792A (zh)
AU (1) AU3333900A (zh)
CA (1) CA2374402A1 (zh)
WO (1) WO2000073455A1 (zh)

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US5583019A (en) 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
WO2001098335A2 (en) 2000-06-20 2001-12-27 Phycotransgenics, Llc Transgenic algae for delivering antigens to an animal
TWI324181B (en) * 2001-04-16 2010-05-01 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
US6399118B1 (en) * 2001-06-29 2002-06-04 Fish Biotech Ltd. Process for storing enriched nematodes
BRPI0412282A (pt) 2003-07-02 2006-09-19 Musc Found For Res Dev imunidade especìfica e não-especìfica induzida de dsrna em crustáceos e outros invertebrados, e veìculos de bioliberação para uso nestes
CN100415869C (zh) * 2004-03-26 2008-09-03 中国科学院海洋研究所 藓羽藻原生质团聚体作为外源基因的受体表达系统的应用
TWI356705B (en) * 2007-10-25 2012-01-21 Internat Chlorella Co Ltd Extracts from chlorella sorokiniana
EP2090648A1 (en) * 2008-02-12 2009-08-19 Institut Francais de Recherche pour l'Exploitation de la Mere(Ifremer) Production of glycosylated polypeptides in microalgae
US20100183523A1 (en) 2009-01-22 2010-07-22 Wagner Richard E Dental composition and method
WO2010084969A1 (ja) * 2009-01-23 2010-07-29 国立大学法人高知大学 藻類を形質転換するために用いられる新規プロモーター
TWI504749B (zh) 2009-03-16 2015-10-21 Dsm Ip Assets Bv 於網黏菌門微生物中生產蛋白質之技術
CN101736025A (zh) * 2009-12-25 2010-06-16 国家海洋局第一海洋研究所 一种对金藻的电击转化方法
CN107746869A (zh) * 2009-12-28 2018-03-02 赛诺菲疫苗技术公司 微藻中异源多肽的生产,微藻胞外体、组合物及其制备方法和用途
CN102703326B (zh) * 2012-02-13 2014-02-19 青岛理工大学 一株高co2耐受性和固定率的微藻及其选育方法
KR101480051B1 (ko) * 2012-05-02 2015-01-09 한국생명공학연구원 트라우스토키트리드 미세조류의 리보좀 단백질 코딩하는 유전자 변이체를 이용한 형질전환체 선별마커
WO2014133159A1 (ja) * 2013-02-28 2014-09-04 株式会社ユーグレナ ユーグレナへの遺伝子導入方法及びその形質転換体
JP2014193154A (ja) * 2013-02-28 2014-10-09 Euglena Co Ltd ユーグレナの形質転換体
JP2014193153A (ja) * 2013-02-28 2014-10-09 Euglena Co Ltd ユーグレナへの遺伝子導入方法
KR101660805B1 (ko) 2014-05-28 2016-09-28 주식회사 바이오에프디엔씨 Glut-1 유전자로 형질전환된 형질전환체 및 그 배양방법
KR101606634B1 (ko) 2014-05-28 2016-03-28 주식회사 바이오에프디엔씨 Maa 대량 생산 방법
KR102013788B1 (ko) 2016-11-04 2019-08-23 한국과학기술연구원 인간상피세포 성장인자 또는 피부침투성 인간상피세포 성장인자 발현용 벡터 및 상기 벡터로 형질전환된 미세조류
CN106591186A (zh) * 2016-12-13 2017-04-26 北京林业大学 一种螺旋藻原生质体的制备方法
CN109706081A (zh) * 2017-10-25 2019-05-03 国家海洋局第三海洋研究所 一种小球藻原生质体制备方法
KR102388144B1 (ko) * 2020-08-06 2022-04-19 한국생명공학연구원 방사무늬김 유래의 유전자를 이용한 마이크로스포린 유사 아미노산을 대량 생산하는 난노클로롭시스 형질전환체의 제조 방법
KR102699731B1 (ko) * 2021-06-18 2024-08-28 국립부경대학교 산학협력단 흰 반점 증후군 바이러스 외피 단백질을 발현하는 형질전환 미세조류를 유효성분으로 포함하는 흰 반점 증후군의 예방 또는 개선용 사료첨가제 조성물 및 이의 용도
KR20230016452A (ko) * 2021-07-26 2023-02-02 그린미네랄 주식회사 클로렐라 불가리스 형질전환용 생광물화 벡터 및 형질전환체
JP2024529454A (ja) * 2021-07-26 2024-08-06 グリーン ミネラル インコーポレイテッド クロレラブルガリス形質転換用ベクターシステム及びクロレラブルガリス形質転換方法
CN113699046A (zh) * 2021-08-10 2021-11-26 吴信忠 含有aif1细胞因子抗体的小球藻及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0376583A (ja) * 1989-08-16 1991-04-02 Hagiwara Yoshihide ヒトタンパク質のラン藻での発現方法
US5804408A (en) * 1991-03-13 1998-09-08 Yoshihide Hagiwara Expression of human SOD in blue green algae
JPH0568572A (ja) * 1991-09-11 1993-03-23 Agency Of Ind Science & Technol サケ成長ホルモンを生産するラン藻シネココツカス
WO1998042748A1 (fr) * 1997-03-24 1998-10-01 Hih.Biocenter Inc. Nouveau polypeptide synthetique

Also Published As

Publication number Publication date
AU3333900A (en) 2000-12-18
JP2003501031A (ja) 2003-01-14
CN1354792A (zh) 2002-06-19
KR20010073152A (ko) 2001-07-31
WO2000073455A1 (en) 2000-12-07
KR20000075076A (ko) 2000-12-15
EP1180145A1 (en) 2002-02-20
KR100443843B1 (ko) 2004-08-09

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Legal Events

Date Code Title Description
FZDE Discontinued