CA2362964C - Fucosyl transferase gene - Google Patents
Fucosyl transferase gene Download PDFInfo
- Publication number
- CA2362964C CA2362964C CA2362964A CA2362964A CA2362964C CA 2362964 C CA2362964 C CA 2362964C CA 2362964 A CA2362964 A CA 2362964A CA 2362964 A CA2362964 A CA 2362964A CA 2362964 C CA2362964 C CA 2362964C
- Authority
- CA
- Canada
- Prior art keywords
- dna molecule
- sequence
- fucosyl transferase
- glcnac
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 125000000969 xylosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)CO1)* 0.000 description 1
Classifications
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C12P21/005—Glycopeptides, glycoproteins
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA270/99 | 1999-02-18 | ||
| AT0027099A AT408446B (de) | 1999-02-18 | 1999-02-18 | Fucosyltransferase-gen |
| PCT/AT2000/000040 WO2000049153A1 (de) | 1999-02-18 | 2000-02-17 | Fucosyltransferase-gen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2362964A1 CA2362964A1 (en) | 2000-08-24 |
| CA2362964C true CA2362964C (en) | 2012-03-27 |
Family
ID=3486087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2362964A Expired - Lifetime CA2362964C (en) | 1999-02-18 | 2000-02-17 | Fucosyl transferase gene |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US20080234471A1 (enExample) |
| EP (3) | EP2062977B1 (enExample) |
| JP (2) | JP5514386B2 (enExample) |
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| AT (2) | AT408446B (enExample) |
| AU (1) | AU771995B2 (enExample) |
| BG (1) | BG65140B1 (enExample) |
| BR (1) | BR0010114A (enExample) |
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| CZ (2) | CZ308081B6 (enExample) |
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| ES (2) | ES2246222T3 (enExample) |
| HR (1) | HRP20010681A2 (enExample) |
| HU (1) | HU230075B1 (enExample) |
| IL (2) | IL144777A0 (enExample) |
| IS (1) | IS6041A (enExample) |
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| NO (1) | NO20013993L (enExample) |
| NZ (1) | NZ513685A (enExample) |
| PL (2) | PL205710B1 (enExample) |
| PT (1) | PT2062977E (enExample) |
| SK (1) | SK286416B6 (enExample) |
| TR (1) | TR200102393T2 (enExample) |
| WO (1) | WO2000049153A1 (enExample) |
| YU (1) | YU58901A (enExample) |
| ZA (1) | ZA200106735B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2350063T3 (es) | 1998-12-09 | 2011-01-17 | Phyton Holdings, Llc | Método para fabricación de glicoproteínas que tienen glicosilación de tipo humano. |
| AT408446B (de) * | 1999-02-18 | 2001-11-26 | Altmann Friedrich Dr | Fucosyltransferase-gen |
| ES2568899T3 (es) | 1999-04-09 | 2016-05-05 | Kyowa Hakko Kirin Co., Ltd. | Procedimiento para controlar la actividad de una molécula inmunofuncional |
| NZ518532A (en) | 1999-10-26 | 2004-02-27 | Plant Res Internat B | Transgenic plant expressing mammalian beta-1,4- galactosyltransferase |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| CA2434364C (en) | 2001-01-19 | 2013-03-19 | The Dow Chemical Company | Method for secretory production of glycoprotein having human-type sugar chain using plant cell |
| WO2003078614A2 (en) | 2002-03-19 | 2003-09-25 | Plant Research International B.V. | Gntiii (udp-n-acethylglucosamine:beta-d mannoside beta (1,4)-n-acethylglucosaminy ltransferase iii) expression in plants |
| CA2799805C (en) | 2002-03-19 | 2016-05-17 | Stichting Dienst Landbouwkundig Onderzoek | Optimizing glycan processing in plants |
| AU2003236020B2 (en) * | 2002-04-09 | 2009-03-19 | Kyowa Hakko Kirin Co., Ltd. | Cell with depression or deletion of the activity of protein participating in GDP-fucose transport |
| CL2003002461A1 (es) | 2002-11-27 | 2005-01-07 | Dow Chemical Company Agroscien | Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas. |
| ATE426033T1 (de) | 2003-08-11 | 2009-04-15 | Greenovation Biotech Gmbh | Promoter sequenzen aus moos und dessen verwendung |
| FI20055398A0 (fi) | 2005-07-08 | 2005-07-08 | Suomen Punainen Risti Veripalv | Menetelmä solupopulaatioiden evaluoimiseksi |
| US20090060921A1 (en) * | 2006-01-17 | 2009-03-05 | Biolex Therapeutics, Inc. | Glycan-optimized anti-cd20 antibodies |
| MX2008009220A (es) | 2006-01-17 | 2008-10-10 | Biolex Therapeutics Inc | Composiciones y metodos para la humanizacion y optimizacion de n-glicanos en plantas. |
| CN102094019B (zh) * | 2007-01-15 | 2012-11-28 | 燕秋 | 用于抑制LeY糖抗原合成的岩藻糖基转移酶Ⅳ的RNA干涉序列及重组干涉质粒 |
| CN102094020B (zh) * | 2007-01-15 | 2012-11-28 | 燕秋 | 用于抑制LeY糖抗原合成的岩藻糖基转移酶I的RNA干涉序列及重组干涉质粒 |
| CN101702919B (zh) | 2007-04-17 | 2014-08-13 | 基金会农业研究服务中心 | 植物通过表达非哺乳动物糖基转移酶而表现出哺乳动物类型的糖基化作用 |
| JP5766947B2 (ja) * | 2007-09-07 | 2015-08-19 | チルドレンズ ホスピタル メディカル センター | 臨床サンプルにおける分泌性のルイス抗原およびシアル化抗原のレベルの疾患リスクの予測指標としての使用 |
| WO2009056155A1 (en) * | 2007-10-31 | 2009-05-07 | Bayer Bioscience N.V. | Method to produce modified plants with altered n-glycosylation pattern |
| EP2166085A1 (en) | 2008-07-16 | 2010-03-24 | Suomen Punainen Risti Veripalvelu | Divalent modified cells |
| PL2944690T3 (pl) | 2010-10-11 | 2018-05-30 | Jennewein Biotechnologie Gmbh | Nowe fukozylotransferazy i ich zastosowanie |
| KR101293658B1 (ko) * | 2010-12-30 | 2013-08-07 | 대한민국 | 알파-1,3-푸코실트랜스퍼라아제 및/또는 베타-1,2-자일로실트렌스퍼라아제 유전자를 포함하는 벼 형질전환용 벡터 및 형질전환된 벼 |
| ES2439507T3 (es) * | 2011-01-20 | 2014-01-23 | Jennewein Biotechnologie Gmbh | Fucosiltransferasas novedosas y sus aplicaciones |
| EP2789686A1 (en) | 2013-04-11 | 2014-10-15 | Greenovation Biotech GmbH | Expression of phosphorylated glycoproteins in plants |
| EP3050973A1 (en) * | 2015-01-30 | 2016-08-03 | Jennewein Biotechnologie GmbH | Fermentation process for producing monosaccharides in free form from nucleotide-activated sugars |
| CN110317799A (zh) * | 2019-07-18 | 2019-10-11 | 江南大学 | 一种人源岩藻糖转移酶8的原核表达方法及其产品 |
| EP3871687A1 (en) | 2020-02-27 | 2021-09-01 | eleva GmbH | Enzyme replacement therapy for treating pompe disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5272066A (en) | 1986-03-07 | 1993-12-21 | Massachusetts Institute Of Technology | Synthetic method for enhancing glycoprotein stability |
| DE69434749T2 (de) | 1993-03-29 | 2007-04-26 | Kyowa Hakko Kogyo Co., Ltd. | Alpha-1,3-Fucosyltransferase |
| US6509149B2 (en) * | 1995-06-06 | 2003-01-21 | Hybridon, Inc. | HPV-specific oligonucleotides |
| US5770420A (en) * | 1995-09-08 | 1998-06-23 | The Regents Of The University Of Michigan | Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures |
| AT408446B (de) * | 1999-02-18 | 2001-11-26 | Altmann Friedrich Dr | Fucosyltransferase-gen |
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1999
- 1999-02-18 AT AT0027099A patent/AT408446B/de not_active IP Right Cessation
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2000
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- 2000-02-17 EP EP09154489.0A patent/EP2062977B1/de not_active Expired - Lifetime
- 2000-02-17 ES ES00904677T patent/ES2246222T3/es not_active Expired - Lifetime
- 2000-02-17 CN CN00805192A patent/CN1360633A/zh active Pending
- 2000-02-17 HU HU0200394A patent/HU230075B1/hu unknown
- 2000-02-17 MX MXPA01008372A patent/MXPA01008372A/es active IP Right Grant
- 2000-02-17 EP EP00904677A patent/EP1151109B1/de not_active Expired - Lifetime
- 2000-02-17 KR KR1020017010518A patent/KR20010108234A/ko not_active Ceased
- 2000-02-17 ES ES09154489.0T patent/ES2444126T3/es not_active Expired - Lifetime
- 2000-02-17 BR BR0010114-1A patent/BR0010114A/pt not_active Application Discontinuation
- 2000-02-17 HR HR20010681A patent/HRP20010681A2/hr not_active Application Discontinuation
- 2000-02-17 PT PT91544890T patent/PT2062977E/pt unknown
- 2000-02-17 WO PCT/AT2000/000040 patent/WO2000049153A1/de not_active Ceased
- 2000-02-17 DE DE50011116T patent/DE50011116D1/de not_active Expired - Lifetime
- 2000-02-17 EP EP05108012A patent/EP1642979A1/de not_active Withdrawn
- 2000-02-17 CZ CZ2008-404A patent/CZ308081B6/cs not_active IP Right Cessation
- 2000-02-17 YU YU58901A patent/YU58901A/sh unknown
- 2000-02-17 NZ NZ513685A patent/NZ513685A/en unknown
- 2000-02-17 AT AT00904677T patent/ATE304053T1/de active
- 2000-02-17 EE EEP200100432A patent/EE200100432A/xx unknown
- 2000-02-17 DK DK00904677T patent/DK1151109T3/da active
- 2000-02-17 CZ CZ20012943A patent/CZ299622B6/cs not_active IP Right Cessation
- 2000-02-17 CA CA2362964A patent/CA2362964C/en not_active Expired - Lifetime
- 2000-02-17 IL IL14477700A patent/IL144777A0/xx active IP Right Grant
- 2000-02-17 PL PL385768A patent/PL205710B1/pl unknown
- 2000-02-17 SK SK1118-2001A patent/SK286416B6/sk not_active IP Right Cessation
- 2000-02-17 AU AU26460/00A patent/AU771995B2/en not_active Expired
- 2000-02-17 JP JP2000599878A patent/JP5514386B2/ja not_active Expired - Lifetime
- 2000-02-17 PL PL363438A patent/PL205785B1/pl unknown
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2001
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- 2001-08-08 IS IS6041A patent/IS6041A/is unknown
- 2001-08-15 ZA ZA200106735A patent/ZA200106735B/en unknown
- 2001-08-16 NO NO20013993A patent/NO20013993L/no unknown
- 2001-09-13 BG BG105899A patent/BG65140B1/bg unknown
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2007
- 2007-06-06 US US11/808,096 patent/US20080234471A1/en not_active Abandoned
- 2007-06-06 US US11/808,097 patent/US8198078B2/en not_active Expired - Fee Related
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2011
- 2011-01-04 JP JP2011000049A patent/JP2011120592A/ja active Pending
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2012
- 2012-05-15 US US13/471,759 patent/US8895806B2/en not_active Expired - Fee Related
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Effective date: 20200217 |