PL2944690T3 - Nowe fukozylotransferazy i ich zastosowanie - Google Patents

Nowe fukozylotransferazy i ich zastosowanie

Info

Publication number
PL2944690T3
PL2944690T3 PL15169876T PL15169876T PL2944690T3 PL 2944690 T3 PL2944690 T3 PL 2944690T3 PL 15169876 T PL15169876 T PL 15169876T PL 15169876 T PL15169876 T PL 15169876T PL 2944690 T3 PL2944690 T3 PL 2944690T3
Authority
PL
Poland
Prior art keywords
applications
fucosyltransferases
novel
novel fucosyltransferases
Prior art date
Application number
PL15169876T
Other languages
English (en)
Inventor
Julia Parkot
Eric HÜFNER
Stefan Jennewein
Original Assignee
Jennewein Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jennewein Biotechnologie Gmbh filed Critical Jennewein Biotechnologie Gmbh
Publication of PL2944690T3 publication Critical patent/PL2944690T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/01214Glycoprotein 3-alpha-L-fucosyltransferase (2.4.1.214)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
PL15169876T 2010-10-11 2010-10-11 Nowe fukozylotransferazy i ich zastosowanie PL2944690T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10187167.1A EP2439264B1 (en) 2010-10-11 2010-10-11 Novel fucosyltransferases and their applications
EP15169876.8A EP2944690B1 (en) 2010-10-11 2010-10-11 Novel fucosyltransferases and their applications

Publications (1)

Publication Number Publication Date
PL2944690T3 true PL2944690T3 (pl) 2018-05-30

Family

ID=43244921

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15169876T PL2944690T3 (pl) 2010-10-11 2010-10-11 Nowe fukozylotransferazy i ich zastosowanie

Country Status (15)

Country Link
US (1) US9441211B2 (pl)
EP (2) EP2439264B1 (pl)
JP (1) JP6097691B2 (pl)
CN (1) CN103201380B (pl)
AU (1) AU2011315656B2 (pl)
BR (1) BR112013008822A8 (pl)
DK (2) DK2944690T3 (pl)
ES (1) ES2663627T3 (pl)
MX (1) MX344691B (pl)
MY (1) MY189569A (pl)
NZ (1) NZ609127A (pl)
PL (1) PL2944690T3 (pl)
RU (1) RU2642307C2 (pl)
SG (1) SG189300A1 (pl)
WO (1) WO2012049083A2 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9173910B2 (en) 2012-02-29 2015-11-03 The General Hospital Corporation Compositions of microbiota and methods related thereto
DK2845905T3 (da) 2013-09-10 2021-06-14 Chr Hansen Hmo Gmbh Fremstilling af oligosaccharider
EP2896628B1 (en) 2014-01-20 2018-09-19 Jennewein Biotechnologie GmbH Process for efficient purification of neutral human milk oligosaccharides (HMOs) from microbial fermentation
PL2927316T3 (pl) 2014-03-31 2019-05-31 Jennewein Biotechnologie Gmbh Całkowita fermentacja oligosacharydów
KR101718681B1 (ko) * 2014-06-23 2017-03-22 서울대학교산학협력단 가용성 단백질 발현량 및 활성이 증대된 헬리코박터 파일로리 유래 α-1,3 푸코실 전달효소의 유전자와 단백질 및 α-1,3 푸코실올리고당 생산에의 응용
AU2015315110B2 (en) * 2014-09-09 2021-04-08 Glycosyn LLC Alpha (1,3) fucosyltransferases for use in the production of fucosylated oligosaccharides
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
EP3212001A4 (en) 2014-10-31 2018-04-25 Whole Biome Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
EP3050973A1 (en) * 2015-01-30 2016-08-03 Jennewein Biotechnologie GmbH Fermentation process for producing monosaccharides in free form from nucleotide-activated sugars
KR101794971B1 (ko) * 2016-02-02 2017-11-08 서울대학교 산학협력단 α-1,3-푸코실락토오즈의 대량 생산 방법
CN105695537B (zh) * 2016-02-29 2019-11-19 福建农林大学 一种降血糖及调节肠道菌群的糖基化浒苔寡糖制备方法
PL3315610T3 (pl) 2016-10-29 2021-06-14 Jennewein Biotechnologie Gmbh Sposób wytwarzania fukozylowanych oligosacharydów
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN106434591A (zh) * 2016-12-13 2017-02-22 福建农林大学 一种岩藻糖基转移酶及其应用
CN106434590A (zh) * 2016-12-13 2017-02-22 福建农林大学 一种岩藻糖基转移酶及其基因工程菌和应用
KR101794972B1 (ko) * 2017-01-26 2017-11-08 서울대학교 산학협력단 α-1,3-푸코실락토오즈의 대량 생산 방법
CN110662842B (zh) * 2017-04-21 2023-03-21 首尔大学校产学协力团 利用谷氨酸棒状杆菌的3-岩藻糖基乳糖的生产方法
EP3425052A1 (en) 2017-07-07 2019-01-09 Jennewein Biotechnologie GmbH Fucosyltransferases and their use in producing fucosylated oligosaccharides
EP3675882A4 (en) 2017-08-30 2021-07-28 Pendulum Therapeutics, Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS
WO2019106620A1 (en) * 2017-11-30 2019-06-06 Glycom A/S Human milk oligosaccharides and synthetic compositions thereof for microbiota modulation
JP2022514743A (ja) 2018-12-18 2022-02-15 インバイオス エン.フェー. 3-フコシルラクトースの産生およびラクトース変換α-1,3-フコシルトランスフェラーゼ酵素
EP3751003A1 (en) 2019-06-12 2020-12-16 Jennewein Biotechnologie GmbH Production of fucosylated oligosaccharides in bacillus
WO2022168992A1 (ja) 2021-02-08 2022-08-11 協和発酵バイオ株式会社 1,3-フコシルトランスフェラーゼ活性を有する蛋白質及びフコース含有糖質の製造法
CN117187206A (zh) * 2023-05-19 2023-12-08 无锡特殊食品与营养健康研究院有限公司 肠道微生物来源的岩藻糖基转移酶及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2125092C1 (ru) * 1991-10-15 1999-01-20 Дзе Скриппс Рисерч Инститьют Способ получения фукозилированного углевода, способ получения фукозилированной сиалилированной углеводной молекулы, реакционная система in vitro
EP0621337A1 (en) * 1993-01-25 1994-10-26 American Cyanamid Company Codon optimized DNA sequence for insect toxin AaIT
US5922577A (en) * 1995-04-11 1999-07-13 Cytel Corporation Enzymatic synthesis of glycosidic linkages
US5728554A (en) 1995-04-11 1998-03-17 Cytel Corporation Enzymatic synthesis of glycosidic linkages
WO1998055630A2 (en) 1997-06-06 1998-12-10 The Governors Of The University Of Alberta Alpha-1,3-fucosyltransferase of helicobacter pylori
US6500661B1 (en) 1998-01-15 2002-12-31 Neose Technologies, Inc. Enzymatic conversion of GDP-mannose to GDP-fucose
AT408446B (de) * 1999-02-18 2001-11-26 Altmann Friedrich Dr Fucosyltransferase-gen
FI19992070A (fi) * 1999-09-28 2001-03-28 Jari Natunen Uudet fukosyloidut oligosakkaridit ja menetelmä niiden valmistamiseksi
TWI237527B (en) 2001-11-06 2005-08-01 Delta Optoelectronics Inc Driver apparatus for a flat-type lamp and driving method for the same
US7326770B2 (en) 2004-01-22 2008-02-05 Neose Technologies, Inc. H. pylori fucosyltransferases
JP2008507297A (ja) * 2004-07-26 2008-03-13 エンゾン ファーマシューティカルズ,インコーポレーテッド 最適化されたインターフェロンβ遺伝子
CN102796743B (zh) * 2006-01-13 2015-11-18 美国政府健康及人类服务部国立卫生研究院 用于在哺乳动物细胞中表达的密码子优化的IL-15和IL-15Rα基因
US7888069B2 (en) * 2006-12-22 2011-02-15 Dow Agrosciences Llc Plant-made west nile virus (WNV) vaccines, vectors and plant codon optimized sequences
JP2009095264A (ja) * 2007-10-15 2009-05-07 Univ Of Ryukyus コドン最適化ロイヤリシン遺伝子
SG171814A1 (en) * 2008-12-19 2011-07-28 Jennewein Biotechnologie Gmbh Synthesis of fucosylated compounds

Also Published As

Publication number Publication date
RU2013120902A (ru) 2014-11-20
DK2944690T3 (en) 2018-04-03
US20130217068A1 (en) 2013-08-22
CN103201380A (zh) 2013-07-10
BR112013008822A2 (pt) 2017-09-19
MY189569A (en) 2022-02-17
SG189300A1 (en) 2013-05-31
WO2012049083A2 (en) 2012-04-19
AU2011315656A1 (en) 2013-05-02
RU2642307C2 (ru) 2018-01-24
US9441211B2 (en) 2016-09-13
EP2439264A1 (en) 2012-04-11
EP2944690A3 (en) 2016-03-09
CN103201380B (zh) 2018-07-24
AU2011315656B2 (en) 2016-01-21
EP2439264B1 (en) 2015-06-03
NZ609127A (en) 2014-10-31
BR112013008822A8 (pt) 2023-01-31
JP2013541952A (ja) 2013-11-21
ES2663627T3 (es) 2018-04-16
WO2012049083A3 (en) 2012-06-14
MX2013004055A (es) 2013-06-05
DK2439264T3 (en) 2015-08-03
JP6097691B2 (ja) 2017-03-15
MX344691B (es) 2016-12-29
EP2944690A2 (en) 2015-11-18
EP2944690B1 (en) 2017-12-20

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