MX2011006371A - Sintesis de compuestos fucosilados. - Google Patents

Sintesis de compuestos fucosilados.

Info

Publication number
MX2011006371A
MX2011006371A MX2011006371A MX2011006371A MX2011006371A MX 2011006371 A MX2011006371 A MX 2011006371A MX 2011006371 A MX2011006371 A MX 2011006371A MX 2011006371 A MX2011006371 A MX 2011006371A MX 2011006371 A MX2011006371 A MX 2011006371A
Authority
MX
Mexico
Prior art keywords
cell
synthesis
transforming
express
fucosylated compounds
Prior art date
Application number
MX2011006371A
Other languages
English (en)
Other versions
MX325472B (es
Inventor
Eric Huefner
Julia Parkot
Stefan Jennewein
Original Assignee
Jennewein Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40550215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011006371(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Jennewein Biotechnologie Gmbh filed Critical Jennewein Biotechnologie Gmbh
Publication of MX2011006371A publication Critical patent/MX2011006371A/es
Publication of MX325472B publication Critical patent/MX325472B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invención se refiere a un método para hacer una célula genéticamente modificada que tiene la capacidad de producir compuestos fucosilados que comprende los pasos que consisten en: transformar la célula para expresar una fucosa cinasa, transformar la célula para expresar una fucosa-1-fosfato guanililtransferasa, transformar la célula para expresar una fucosiltransferasa.
MX2011006371A 2008-12-19 2009-12-18 Sintesis de compuestos fucosilados. MX2011006371A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08172267 2008-12-19
PCT/EP2009/067531 WO2010070104A1 (en) 2008-12-19 2009-12-18 Synthesis of fucosylated compounds

Publications (2)

Publication Number Publication Date
MX2011006371A true MX2011006371A (es) 2011-09-27
MX325472B MX325472B (es) 2014-11-20

Family

ID=40550215

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011006371A MX2011006371A (es) 2008-12-19 2009-12-18 Sintesis de compuestos fucosilados.

Country Status (15)

Country Link
US (2) US20110300584A1 (es)
EP (1) EP2379708B1 (es)
JP (1) JP5726751B2 (es)
CN (1) CN102257128A (es)
AU (1) AU2009329543B2 (es)
BR (1) BRPI0923433B1 (es)
CO (1) CO6362044A2 (es)
HK (1) HK1159173A1 (es)
IN (1) IN2011MU01050A (es)
MX (1) MX2011006371A (es)
MY (1) MY183602A (es)
NZ (1) NZ593448A (es)
RU (1) RU2584599C2 (es)
SG (1) SG171814A1 (es)
WO (1) WO2010070104A1 (es)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ597129A (en) 2009-06-08 2012-12-21 Jennewein Biotechnologie Gmbh Hmo synthesis
AU2015215937B2 (en) * 2010-07-12 2017-03-16 Inbiose N.V. Metabolically engineered organisms for the production of added value bio-products
ES2663627T3 (es) * 2010-10-11 2018-04-16 Jennewein Biotechnologie Gmbh Fucosiltransferasas novedosas y sus aplicaciones
CN102120999A (zh) * 2010-12-17 2011-07-13 天津科技大学 利用基因工程菌株耦合发酵合成人乳岩藻糖基化寡糖的方法
NZ612504A (en) 2010-12-31 2015-02-27 Abbott Lab Methods for reducing the incidence of oxidative stress using human milk oligosaccharides, vitamin c and anti-inflammatory agents
ES2667393T3 (es) 2010-12-31 2018-05-10 Abbott Laboratories Oligosacáridos de leche humana para modular inflamación
WO2012092160A2 (en) 2010-12-31 2012-07-05 Abbott Laboratories Human milk oligosaccharides to promote growth of beneficial bacteria
WO2012092157A2 (en) 2010-12-31 2012-07-05 Abbott Laboratories Nutritional formulations including human milk oligosaccharides and antioxidants and uses thereof
NZ613180A (en) 2010-12-31 2015-02-27 Abbott Lab Methods of using human milk oligosaccharides for improving airway respiratory health
MY171620A (en) 2010-12-31 2019-10-21 Abbott Lab Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers or children using human milk oligosaccharides
WO2012092153A1 (en) 2010-12-31 2012-07-05 Abbott Laboratories Nutritional compositions comprising human milk oligosaccharides and nucleotides and uses thereof for treating and/or preventing enteric viral infection
ES2439507T3 (es) * 2011-01-20 2014-01-23 Jennewein Biotechnologie Gmbh Fucosiltransferasas novedosas y sus aplicaciones
WO2012112777A2 (en) * 2011-02-16 2012-08-23 Glycosyn LLC Biosynthesis of human milk oligosaccharides in engineered bacteria
JP5881035B2 (ja) * 2011-03-17 2016-03-09 国立研究開発法人産業技術総合研究所 酵母を用いた糖ヌクレオチドの合成法
EP2895592A1 (en) 2011-03-23 2015-07-22 Société Industrielle Limousine d'Application Biologique (SILAB) A yeast recombinant cell capable of producing gdp-fucose
NL2007268C2 (en) 2011-08-16 2013-02-19 Friesland Brands Bv Nutritional compositions comprising human milk oligosaccharides and uses thereof.
CN113662199A (zh) 2011-08-29 2021-11-19 雅培制药有限公司 用于预防胃肠道损伤和/或促进胃肠道愈合的人乳寡糖
DK2791367T3 (da) * 2011-12-16 2019-07-01 Inbiose Nv Mutante mikroorganismer til syntetisering af colansyre, mannosylerede og/eller fucosylerede oligosaccharider
US9029136B2 (en) 2012-07-25 2015-05-12 Glycosyn LLC Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
EP2900829B1 (en) 2012-09-25 2019-06-26 Glycom A/S Glycoconjugate synthesis
DK2728009T3 (da) 2012-10-31 2017-11-06 Jennewein Biotechnologie Gmbh Fremgangsmåde til fremstilling af monosaccharider
US9834574B2 (en) 2012-11-13 2017-12-05 Glycom A/S Crystalline 3-O-fucosyllactose
WO2014086373A1 (en) 2012-12-07 2014-06-12 Glycom A/S Crystallisation of human milk oligosaccharides (hmo)
US10364449B2 (en) 2013-09-06 2019-07-30 Glycom A/S Fermentative production of oligosaccharides
EP3041946B1 (en) 2013-09-06 2021-05-26 Glycom A/S Fermentative production of oligosaccharides
EP3572520A1 (en) 2013-09-10 2019-11-27 Jennewein Biotechnologie GmbH Production of oligosaccharides
ES2701163T3 (es) 2014-01-20 2019-02-21 Jennewein Biotechnologie Gmbh Procedimiento para la purificación eficiente de oligosacáridos de la leche humana (HMO) neutros a partir de la fermentación microbiana
WO2015188834A1 (en) 2014-06-11 2015-12-17 Glycom A/S Separation of 2'-o-fucosyllactose from fermentation broth
US11926858B2 (en) 2014-06-27 2024-03-12 Glycom A/S Oligosaccharide production
WO2015197082A1 (en) 2014-06-27 2015-12-30 Glycom A/S Oligosaccharide production
US20170204443A1 (en) * 2014-07-14 2017-07-20 Basf Se Biotechnological production of lnt, lnnt and the fucosylated derivatives thereof
DE202015009775U1 (de) 2014-12-16 2020-02-05 Glycom A/S Abscheidung von 2'-FL aus einer Fermentationsbrühe
WO2017101958A1 (en) 2015-12-18 2017-06-22 Glycom A/S Fermentative production of oligosaccharides
KR20240016454A (ko) 2016-08-31 2024-02-06 올리고사이언스 바이오테크놀로지 게엠베하 송아지 비육에서 인간 모유 올리고당류의 용도
ES2856749T3 (es) * 2016-10-29 2021-09-28 Chr Hansen Hmo Gmbh Proceso para la producción de oligosacáridos fucosilados
WO2019003133A1 (en) 2017-06-30 2019-01-03 Glycom A/S PURIFICATION OF OLIGOSACCHARIDES
US11505567B2 (en) 2017-07-12 2022-11-22 Glycom A/S Amorphous mixture comprising a neutral mono- or oligosaccharide and an acidic non-carbohydrate component
EP3486326A1 (en) 2017-11-21 2019-05-22 Jennewein Biotechnologie GmbH Method for the purification of n-acetylneuraminic acid from a fermentation broth
NZ764680A (en) 2017-12-08 2023-06-30 Chr Hansen Hmo Gmbh Spray-dried 3-fucosyllactose
EP3494804A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried 3-fucosyllactose
EP3494805A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried tetrasaccharides
EP3494806A1 (en) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried lacto-n-fucopentaose
EP3524067A1 (en) 2018-02-08 2019-08-14 Jennewein Biotechnologie GmbH Spray-dried mixture of human milk oligosaccharides
EP3494807A1 (en) 2017-12-11 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried sialyllactose
KR20210080420A (ko) 2018-10-18 2021-06-30 바스프 에스이 결정질 2'-푸코실락토오스를 수득하는 방법
JP2022514350A (ja) 2018-12-19 2022-02-10 ビーエーエスエフ ソシエタス・ヨーロピア バイオマス及び少なくとも１種のオリゴ糖を含む溶液からバイオマスを分離する方法
WO2021019104A2 (en) 2019-09-18 2021-02-04 Basf Se A production host for producing human milk oligosaccharides
CN110672756B (zh) * 2019-11-07 2020-12-29 江南大学 一种奶粉中2’-岩藻糖基乳糖含量的检测方法
WO2021094133A2 (en) 2019-11-13 2021-05-20 Basf Se Enzymatic hydrolysis of 2',3-difucosyllactose
KR20220116504A (ko) 2019-12-19 2022-08-23 바스프 에스이 정밀 화학물의 제조에서 공시 수율, 탄소-전환-효율 및 탄소 기질 적응성의 증가
EP3848471A1 (en) 2020-01-10 2021-07-14 Chr. Hansen HMO GmbH Sequential fermentative production of oligosaccharides
EP3922727A1 (en) 2020-06-12 2021-12-15 Basf Se Method for separating biomass from a solution comprising biomass and at least one aroma compound
CN116075517A (zh) 2020-06-12 2023-05-05 巴斯夫欧洲公司 改进的发酵液的脱矿化与诸如寡糖的精细化学品的纯化
WO2022013143A1 (en) 2020-07-13 2022-01-20 Glycom A/S Oligosaccharide production
JP2024516207A (ja) 2021-05-17 2024-04-12 ディーエスエム アイピー アセッツ ビー．ブイ． インベルターゼ／スクロースヒドロラーゼを発現する微生物株
WO2022242860A1 (en) 2021-05-20 2022-11-24 Chr. Hansen A/S Sequential fermentative production of oligosaccharides
WO2024046993A1 (en) 2022-08-29 2024-03-07 Chr. Hansen A/S Process for the production of a purified human milk oligosaccharide derived from a microbial fermentation process

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2125092C1 (ru) * 1991-10-15 1999-01-20 Дзе Скриппс Рисерч Инститьют Способ получения фукозилированного углевода, способ получения фукозилированной сиалилированной углеводной молекулы, реакционная система in vitro
US6238894B1 (en) 1998-11-04 2001-05-29 Diane Taylor α1,2 fucosyltransferase
MXPA01004982A (es) 1998-11-18 2004-09-27 Neose Technologies Inc Manufactura de bajo costo de oligosacaridos.
WO2001077313A1 (fr) * 2000-04-11 2001-10-18 Kyowa Hakko Kogyo Co., Ltd. α1,2-FUCOSYLTRANSFERASE ET PROCEDE SERVANT A PREPARER UN GLUCIDE COMPLEXE CONTENANT FUCOSE
AU7684201A (en) 2000-06-28 2002-01-08 Glycofi Inc Methods for producing modified glycoproteins
US20020132320A1 (en) 2001-01-10 2002-09-19 Wang Peng George Glycoconjugate synthesis using a pathway-engineered organism
WO2003018794A1 (en) * 2001-08-24 2003-03-06 Kyowa Hakko Kogyo Co., Ltd. α-1,2-FUCOSYL TRANSFERASE AND DNA ENCODING THE SAME
FR2840920B1 (fr) * 2002-06-18 2006-06-23 Biochimie Appliquee Soc Nouveau microorganisme de la famille des enterobacteriaceae
EP1689348B1 (en) * 2003-12-05 2013-05-15 Children's Hospital Medical Center Oligosaccharide compositions and use thereof in the treatment of infection
US7326770B2 (en) * 2004-01-22 2008-02-05 Neose Technologies, Inc. H. pylori fucosyltransferases
WO2006034225A2 (en) 2004-09-17 2006-03-30 Neose Technologies, Inc. Production of oligosaccharides by microorganisms
WO2006135075A1 (en) * 2005-06-17 2006-12-21 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family with enhanced expression of the fucpikur operon
US8507227B2 (en) * 2006-03-09 2013-08-13 Centre National De La Recherche Scientifique (Cnrs) Method of producing sialylated oligosaccharides
US20070221747A1 (en) 2006-03-22 2007-09-27 Siemens Vdo Automotive Corporation Super imposed signal for an actuator and heater of a fuel injector
AU2008227024A1 (en) * 2007-03-07 2008-09-18 Glycofi, Inc. Production of glycoproteins with modified fucosylation

Also Published As

Publication number Publication date
US11390855B2 (en) 2022-07-19
AU2009329543B2 (en) 2015-04-16
MX325472B (es) 2014-11-20
WO2010070104A1 (en) 2010-06-24
MY183602A (en) 2021-03-02
IN2011MU01050A (es) 2011-12-30
BRPI0923433B1 (pt) 2021-06-01
EP2379708A1 (en) 2011-10-26
BRPI0923433A2 (pt) 2015-08-11
EP2379708B1 (en) 2016-04-27
US20110300584A1 (en) 2011-12-08
JP5726751B2 (ja) 2015-06-03
JP2012512643A (ja) 2012-06-07
US20190382737A1 (en) 2019-12-19
RU2584599C2 (ru) 2016-05-20
RU2011129780A (ru) 2013-01-27
AU2009329543A1 (en) 2010-06-24
CN102257128A (zh) 2011-11-23
NZ593448A (en) 2012-06-29
CO6362044A2 (es) 2012-01-20
SG171814A1 (en) 2011-07-28
HK1159173A1 (zh) 2012-07-27

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