CA2266479C - Vitamin d analogues - Google Patents
Vitamin d analogues Download PDFInfo
- Publication number
- CA2266479C CA2266479C CA002266479A CA2266479A CA2266479C CA 2266479 C CA2266479 C CA 2266479C CA 002266479 A CA002266479 A CA 002266479A CA 2266479 A CA2266479 A CA 2266479A CA 2266479 C CA2266479 C CA 2266479C
- Authority
- CA
- Canada
- Prior art keywords
- compound
- mmol
- seco
- ether
- title compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9622590.9 | 1996-10-30 | ||
GBGB9622590.9A GB9622590D0 (en) | 1996-10-30 | 1996-10-30 | Chemical compounds |
PCT/DK1997/000472 WO1998018759A1 (en) | 1996-10-30 | 1997-10-27 | Vitamin d analogues |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2266479A1 CA2266479A1 (en) | 1998-05-07 |
CA2266479C true CA2266479C (en) | 2008-09-23 |
Family
ID=10802170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002266479A Expired - Lifetime CA2266479C (en) | 1996-10-30 | 1997-10-27 | Vitamin d analogues |
Country Status (21)
Country | Link |
---|---|
US (1) | US6310226B1 (ja) |
EP (1) | EP0937038B1 (ja) |
JP (1) | JP3907010B2 (ja) |
KR (1) | KR100526644B1 (ja) |
CN (1) | CN1107669C (ja) |
AT (1) | ATE216361T1 (ja) |
AU (1) | AU722659B2 (ja) |
CA (1) | CA2266479C (ja) |
CZ (1) | CZ290933B6 (ja) |
DE (1) | DE69712086T2 (ja) |
DK (1) | DK0937038T3 (ja) |
ES (1) | ES2173425T3 (ja) |
GB (1) | GB9622590D0 (ja) |
HK (1) | HK1022298A1 (ja) |
HU (1) | HUP9904333A3 (ja) |
NZ (1) | NZ334328A (ja) |
PL (1) | PL192660B1 (ja) |
PT (1) | PT937038E (ja) |
RO (1) | RO120338B1 (ja) |
RU (1) | RU2183622C2 (ja) |
WO (1) | WO1998018759A1 (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8860298A (en) * | 1997-07-17 | 1999-02-10 | F. Hoffmann-La Roche Ag | Dihomo-seco-cholestanes with two unsaturated bones in the side chain |
AU2003291810A1 (en) * | 2002-11-18 | 2004-06-15 | Teva Pharmaceutical Industries Ltd. | A crystallization method for purification of calcipotriene |
SI1730108T1 (sl) * | 2004-03-18 | 2008-08-31 | Leo Pharma As | Stereoselektivna sinteza analogov vitamina D |
EP1812011A1 (en) | 2004-11-12 | 2007-08-01 | Bioxell S.p.a. | Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer |
EP1883626B1 (en) * | 2005-04-25 | 2017-10-11 | OPKO Ireland Global Holdings, Ltd. | Low-calcemic 16,23-diene 25-oxime analogs of 1alpha,25-dihydroxy vitamin d3 |
CA2661546A1 (en) | 2006-08-25 | 2008-02-28 | Cougar Biotechnology, Inc. | Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same |
US20080051380A1 (en) * | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
US20080051375A1 (en) * | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same |
CN101505725A (zh) * | 2006-08-29 | 2009-08-12 | 特瓦制药工业有限公司 | 包含含维生素D的化合物和皮质类固醇化合物的具有低pH相容性的稳定的药理学活性组合物 |
EA201691980A1 (ru) | 2009-01-27 | 2017-07-31 | БЕРГ ЭлЭлСи | Способы уменьшения побочных эффектов, связанных с химиотерапией |
US20120184514A1 (en) * | 2009-07-01 | 2012-07-19 | Vitamin Derivatives Inc. | Vitamin d compounds and methods for preparing same |
SG178382A1 (en) | 2009-08-14 | 2012-04-27 | Berg Biosystems Llc | Vitamin d3 and analogs thereof for treating alopecia |
WO2014194133A1 (en) | 2013-05-29 | 2014-12-04 | Berg Llc | Preventing or mitigating chemotherapy induced alopecia using vitamin d |
JP2019522032A (ja) | 2016-07-29 | 2019-08-08 | ヤンセン ファーマシューティカ エヌ.ベー. | 前立腺癌の治療方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8914963D0 (en) * | 1989-06-29 | 1989-08-23 | Leo Pharm Prod Ltd | Chemical compounds |
US5260290A (en) * | 1990-02-14 | 1993-11-09 | Wisconsin Alumni Research Foundation | Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives |
GB9017890D0 (en) * | 1990-08-15 | 1990-09-26 | Leo Pharm Prod Ltd | Chemical compounds i |
GB9206648D0 (en) * | 1992-03-26 | 1992-05-06 | Leo Pharm Prod Ltd | Chemical compounds |
GB9223061D0 (en) * | 1992-11-04 | 1992-12-16 | Leo Pharm Prod Ltd | Chemical compounds |
US5449668A (en) | 1993-06-04 | 1995-09-12 | Duphar International Research B.V. | Vitamin D compounds and method of preparing these compounds |
US5552392A (en) | 1993-11-03 | 1996-09-03 | Wisconsin Alumni Research Foundation | Method of treating hypoparathyroidism with (20S) vitamin D compounds |
JP3228488B2 (ja) | 1993-12-24 | 2001-11-12 | 株式会社クラレ | 20−エピステロイド誘導体およびその製造方法 |
JPH0888281A (ja) * | 1994-09-19 | 1996-04-02 | Fujitsu Ltd | 半導体装置 |
IL118156A (en) * | 1995-05-09 | 2001-08-26 | Duphar Int Res | Vitamin d compounds, their preparation and pharmaceutical compositions containing them |
-
1996
- 1996-10-30 GB GBGB9622590.9A patent/GB9622590D0/en active Pending
-
1997
- 1997-10-27 PL PL333068A patent/PL192660B1/pl unknown
- 1997-10-27 WO PCT/DK1997/000472 patent/WO1998018759A1/en active IP Right Grant
- 1997-10-27 EP EP97910261A patent/EP0937038B1/en not_active Expired - Lifetime
- 1997-10-27 RO RO99-00325A patent/RO120338B1/ro unknown
- 1997-10-27 AU AU47717/97A patent/AU722659B2/en not_active Expired
- 1997-10-27 ES ES97910261T patent/ES2173425T3/es not_active Expired - Lifetime
- 1997-10-27 CA CA002266479A patent/CA2266479C/en not_active Expired - Lifetime
- 1997-10-27 RU RU99111777/04A patent/RU2183622C2/ru active
- 1997-10-27 DE DE69712086T patent/DE69712086T2/de not_active Expired - Lifetime
- 1997-10-27 HU HU9904333A patent/HUP9904333A3/hu unknown
- 1997-10-27 AT AT97910261T patent/ATE216361T1/de active
- 1997-10-27 CN CN97198407A patent/CN1107669C/zh not_active Expired - Lifetime
- 1997-10-27 CZ CZ19991358A patent/CZ290933B6/cs not_active IP Right Cessation
- 1997-10-27 JP JP51993198A patent/JP3907010B2/ja not_active Expired - Lifetime
- 1997-10-27 DK DK97910261T patent/DK0937038T3/da active
- 1997-10-27 NZ NZ334328A patent/NZ334328A/xx not_active IP Right Cessation
- 1997-10-27 US US09/297,387 patent/US6310226B1/en not_active Expired - Lifetime
- 1997-10-27 KR KR10-1999-7002315A patent/KR100526644B1/ko not_active IP Right Cessation
- 1997-10-27 PT PT97910261T patent/PT937038E/pt unknown
-
2000
- 2000-02-29 HK HK00101222A patent/HK1022298A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT937038E (pt) | 2002-09-30 |
GB9622590D0 (en) | 1997-01-08 |
DE69712086D1 (de) | 2002-05-23 |
EP0937038B1 (en) | 2002-04-17 |
AU722659B2 (en) | 2000-08-10 |
CZ290933B6 (cs) | 2002-11-13 |
HUP9904333A2 (hu) | 2000-06-28 |
CN1107669C (zh) | 2003-05-07 |
WO1998018759A1 (en) | 1998-05-07 |
AU4771797A (en) | 1998-05-22 |
NZ334328A (en) | 2000-09-29 |
HUP9904333A3 (en) | 2001-06-28 |
JP2001503403A (ja) | 2001-03-13 |
PL192660B1 (pl) | 2006-11-30 |
DK0937038T3 (da) | 2002-07-15 |
CA2266479A1 (en) | 1998-05-07 |
US6310226B1 (en) | 2001-10-30 |
ES2173425T3 (es) | 2002-10-16 |
DE69712086T2 (de) | 2002-11-14 |
ATE216361T1 (de) | 2002-05-15 |
EP0937038A1 (en) | 1999-08-25 |
RO120338B1 (ro) | 2005-12-30 |
CZ135899A3 (cs) | 1999-07-14 |
CN1232448A (zh) | 1999-10-20 |
KR20000036233A (ko) | 2000-06-26 |
PL333068A1 (en) | 1999-11-08 |
JP3907010B2 (ja) | 2007-04-18 |
RU2183622C2 (ru) | 2002-06-20 |
KR100526644B1 (ko) | 2005-11-08 |
HK1022298A1 (en) | 2000-08-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA1340614C (en) | Cyclopentano-vitamin d analogs | |
EP0637299B1 (de) | 20-methyl-substituierte vitamin d-derivate | |
CA2266479C (en) | Vitamin d analogues | |
RU2037484C1 (ru) | Аналог витамина д | |
US5710142A (en) | Vitamin D analogues | |
US6399797B1 (en) | Vitamin D analogues | |
NZ253026A (en) | 20-alkynyl-9,10-seco-pregna-5(z),7(e),10(19),17(20)(e)-tetraene (vitamin d) derivatives and pharmaceutical compositions | |
EP0865428B1 (en) | Vitamin d analogues | |
RU2163234C2 (ru) | Аналоги витамина d, способ их получения, диастереоизомер, фармацевтическая композиция | |
AU719081B2 (en) | Vitamin D3 derivatives | |
KR20010109357A (ko) | 비타민 d 동족체 및 이의 약제학적 용도 | |
CA2222785C (en) | Vitamin d analogues |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20171027 |