CA1251462C - - Google Patents

Info

Publication number
CA1251462C
CA1251462C CA 481204 CA481204A CA1251462C CA 1251462 C CA1251462 C CA 1251462C CA 481204 CA481204 CA 481204 CA 481204 A CA481204 A CA 481204A CA 1251462 C CA1251462 C CA 1251462C
Authority
CA
Canada
Prior art keywords
glycero
diacyl
phosphoethanolamines
phosphocholines
phosphoethanolamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA 481204
Other languages
English (en)
Other versions
CA1244462A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA000552926A priority Critical patent/CA1251462A/en
Application granted granted Critical
Publication of CA1244462A publication Critical patent/CA1244462A/en
Publication of CA1251462C publication Critical patent/CA1251462C/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Epoxy Resins (AREA)
CA000481204A 1984-05-15 1985-05-09 GLYCEROPHOSPHOCHOLINE AND GLYCEROPHOSPHOETHANOLAMINE DERIVATIVES; PREPARATION AND USE Expired CA1244462A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000552926A CA1251462A (en) 1984-05-15 1987-11-26 Preparation of acylated glycerophosphocholines and glycerophosphoethanolamines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0159084A AT383130B (de) 1984-05-15 1984-05-15 Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000552926A Division CA1251462A (en) 1984-05-15 1987-11-26 Preparation of acylated glycerophosphocholines and glycerophosphoethanolamines

Publications (2)

Publication Number Publication Date
CA1244462A CA1244462A (en) 1988-11-08
CA1251462C true CA1251462C (no) 1989-03-21

Family

ID=3516711

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000481204A Expired CA1244462A (en) 1984-05-15 1985-05-09 GLYCEROPHOSPHOCHOLINE AND GLYCEROPHOSPHOETHANOLAMINE DERIVATIVES; PREPARATION AND USE

Country Status (24)

Country Link
US (2) US4622180A (no)
EP (1) EP0161519B1 (no)
JP (1) JPS60252490A (no)
KR (1) KR920009556B1 (no)
CN (1) CN1014791B (no)
AT (2) AT383130B (no)
AU (1) AU565316B2 (no)
BR (1) BR8502293A (no)
CA (1) CA1244462A (no)
DD (2) DD245668A1 (no)
DE (1) DE3563533D1 (no)
DK (2) DK167441C (no)
ES (2) ES8603900A1 (no)
FI (1) FI77663C (no)
HU (2) HU199486B (no)
IE (1) IE58511B1 (no)
IL (1) IL75133A (no)
NO (1) NO163100C (no)
NZ (1) NZ212067A (no)
PH (2) PH21831A (no)
SU (2) SU1400511A3 (no)
TR (1) TR22204A (no)
YU (2) YU45719B (no)
ZA (1) ZA853697B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT383130B (de) * 1984-05-15 1987-05-25 Chemie Linz Ag Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin
DE3638687A1 (de) * 1986-11-13 1988-05-19 Lentia Gmbh Einstufiges verfahren zur herstellung von gemischt substituierten 1,2-di-acyl-sn-glycero-3-phosphocholinen
AT388165B (de) * 1986-12-10 1989-05-10 Chemie Linz Ag Einstufiges verfahren zur herstellung von gemischt substituierten 1,2-di-acyl-sn-glycero-3- phosphocholinen
JP2657486B2 (ja) * 1987-02-20 1997-09-24 花王株式会社 洗浄剤組成物
US5144045A (en) * 1990-11-13 1992-09-01 American Cyanamid Company Phosphocholine derivative inhibitors of phospholipase A2
US5698537A (en) * 1996-06-18 1997-12-16 Clarion Pharmaceuticals Inc. Method of lowering the viscosity of mucus
US6838452B2 (en) * 2000-11-24 2005-01-04 Vascular Biogenics Ltd. Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
JP2007502805A (ja) * 2003-08-18 2007-02-15 ビーティージー・インターナショナル・リミテッド 神経変性状態の処置
US7807847B2 (en) 2004-07-09 2010-10-05 Vascular Biogenics Ltd. Process for the preparation of oxidized phospholipids
GB0425932D0 (en) * 2004-11-25 2004-12-29 Btg Int Ltd Structured phospholipids
GB0504362D0 (en) 2005-03-02 2005-04-06 Btg Int Ltd Cytokine modulators
US8569529B2 (en) 2007-01-09 2013-10-29 Vascular Biogenics Ltd. High-purity phospholipids
US9006217B2 (en) 2007-01-09 2015-04-14 Vascular Biogenics Ltd. High-purity phospholipids
EP2348866B1 (en) * 2008-11-06 2015-01-07 Vascular Biogenics Ltd. Oxidized lipid compounds and uses thereof
CN104017019A (zh) * 2014-06-12 2014-09-03 东南大学 一种氮芥-甘油磷脂酰胆碱化合物的合成方法
ES2855299T3 (es) 2014-11-26 2021-09-23 Vascular Biogenics Ltd Lípidos oxidados y tratamiento o prevención de la fibrosis
US9771385B2 (en) 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids
CZ308596B6 (cs) * 2017-04-03 2020-12-23 Ústav molekulární genetiky AV ČR, v. v. i. Deriváty fosfolipidů a jejich použití jako léčiva
PL232663B1 (pl) * 2017-06-30 2019-07-31 Univ Przyrodniczy We Wroclawiu Fosfatydylocholiny oraz sposób ich otrzymywania
PL232298B1 (pl) * 2017-06-30 2019-06-28 Univ Przyrodniczy We Wroclawiu Sposób otrzymywania fosfatydylocholiny zawierającej ibuprofen w pozycji sn-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2820893C2 (de) * 1978-05-12 1986-02-20 A. Nattermann & Cie GmbH, 5000 Köln Strukturanaloga von natürlichen Phospholipiden und Verfahren zur Herstellung dieser Verbindungen
IT1123187B (it) * 1979-09-17 1986-04-30 Lpb Ist Farm Processo per la preparazione di l-alfa-glicerilfosforilcolina
DE3130867A1 (de) * 1981-08-04 1983-02-24 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Zwischenprodukte zur herstellung von glycerinderivaten
AT383130B (de) * 1984-05-15 1987-05-25 Chemie Linz Ag Verfahren zur herstellung von an c1 und c2 verschieden substituierten phosphatidylcholinen und phosphatidylethanolaminen ueber die neuen verbindungen 1-0-tritylglycerophosphocholin beziehungsweise (1-0,n-ditrityl)-glycerophosphoethanolamin

Also Published As

Publication number Publication date
IL75133A (en) 1988-12-30
US4622180A (en) 1986-11-11
FI851781A0 (fi) 1985-05-07
SU1422999A3 (ru) 1988-09-07
FI77663C (fi) 1989-04-10
US4717512A (en) 1988-01-05
YU45719B (sh) 1992-07-20
EP0161519A2 (de) 1985-11-21
KR850008677A (ko) 1985-12-21
EP0161519B1 (de) 1988-06-29
ES8603899A1 (es) 1986-01-01
DK212185D0 (da) 1985-05-14
TR22204A (tr) 1986-09-24
DD245668A1 (de) 1987-05-13
ES543146A0 (es) 1986-01-01
HU203555B (en) 1991-08-28
HUT39454A (en) 1986-09-29
CN1014791B (zh) 1991-11-20
FI851781L (fi) 1985-11-16
YU81685A (en) 1987-10-31
DK212185A (da) 1985-11-16
DE3563533D1 (en) 1988-08-04
HU199486B (en) 1990-02-28
CN85104463A (zh) 1986-12-10
AU565316B2 (en) 1987-09-10
DD233130A1 (de) 1986-02-19
NO163100B (no) 1989-12-27
ATE35416T1 (de) 1988-07-15
YU81585A (en) 1987-10-31
DK98192A (da) 1992-08-03
ES543147A0 (es) 1986-01-01
CA1244462A (en) 1988-11-08
EP0161519A3 (en) 1986-02-12
JPH0482157B2 (no) 1992-12-25
NZ212067A (en) 1988-10-28
KR920009556B1 (ko) 1992-10-19
NO163100C (no) 1990-04-04
SU1400511A3 (ru) 1988-05-30
ES8603900A1 (es) 1986-01-01
AT383130B (de) 1987-05-25
ATA159084A (de) 1986-10-15
AU4244885A (en) 1985-11-21
IE851136L (en) 1985-11-15
DK167441C (da) 1994-04-18
IL75133A0 (en) 1985-09-29
NO851928L (no) 1985-11-18
BR8502293A (pt) 1986-01-21
FI77663B (fi) 1988-12-30
IE58511B1 (en) 1993-10-06
JPS60252490A (ja) 1985-12-13
DK167441B (da) 1993-11-01
ZA853697B (en) 1986-01-29
DK98192D0 (da) 1992-08-03
YU45720B (sh) 1992-07-20
PH21831A (en) 1988-03-17
PH23978A (en) 1990-02-09

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Legal Events

Date Code Title Description
MKEX Expiry