CA1246086A - Iminothiazolidine derivatives - Google Patents

Iminothiazolidine derivatives

Info

Publication number
CA1246086A
CA1246086A CA000480005A CA480005A CA1246086A CA 1246086 A CA1246086 A CA 1246086A CA 000480005 A CA000480005 A CA 000480005A CA 480005 A CA480005 A CA 480005A CA 1246086 A CA1246086 A CA 1246086A
Authority
CA
Canada
Prior art keywords
formula
compound
amino
group
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000480005A
Other languages
English (en)
French (fr)
Inventor
Karoly Lempert
Gyula Hornyak
Ferenc Bartha
Jozsef Nyitrai
Jozsef Fetter
Gabor Doleschall
Gyula Simig
Karoly Zauer
Lujza Petocz
Eniko Nee Kiszelly Szirt
Katalin Grasser
Edit Nee Poldermann Berenyi
Antal Feller
Peter Huszthy
Etelka Pjeczka
Zsuzsanna Orr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egis Gyógyszergyár Zrt
Original Assignee
Egis Gyógyszergyár Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyógyszergyár Zrt filed Critical Egis Gyógyszergyár Zrt
Application granted granted Critical
Publication of CA1246086A publication Critical patent/CA1246086A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA000480005A 1984-04-25 1985-04-24 Iminothiazolidine derivatives Expired CA1246086A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU1581/84 1984-04-25
HU841581A HU191408B (en) 1984-04-25 1984-04-25 Process for preparing new imino-thiazolidine derivatives

Publications (1)

Publication Number Publication Date
CA1246086A true CA1246086A (en) 1988-12-06

Family

ID=10955127

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000480005A Expired CA1246086A (en) 1984-04-25 1985-04-24 Iminothiazolidine derivatives

Country Status (24)

Country Link
US (1) US4665083A (enExample)
JP (1) JPS6127974A (enExample)
AT (1) AT394555B (enExample)
BE (1) BE902249A (enExample)
CA (1) CA1246086A (enExample)
CH (1) CH664564A5 (enExample)
CS (1) CS255884B2 (enExample)
DD (1) DD231790A5 (enExample)
DE (1) DE3514843A1 (enExample)
DK (1) DK183585A (enExample)
ES (3) ES8608499A1 (enExample)
FI (1) FI82454C (enExample)
FR (1) FR2563519B1 (enExample)
GB (1) GB2159814B (enExample)
GR (1) GR851006B (enExample)
HU (1) HU191408B (enExample)
IT (1) IT1208532B (enExample)
NL (1) NL8501184A (enExample)
NO (1) NO164417C (enExample)
PH (1) PH20995A (enExample)
PL (3) PL145084B1 (enExample)
PT (1) PT80336B (enExample)
SE (1) SE464813B (enExample)
SU (3) SU1366058A3 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3442757A1 (de) * 1984-11-23 1986-05-28 Wella Ag, 6100 Darmstadt Verwendung von 2-nitroanilinderivaten in haarfaerbemitteln und neue 2-nitroanilinderivate
US4867782A (en) * 1988-07-01 1989-09-19 Ici Americas Inc. Novel herbicidal 2-sulfonyliminothiazolidines
US5266701A (en) * 1988-07-01 1993-11-30 Ici Americas Inc. Process for production of 2-iminothiazolidines and oxazolidines
CA2063865A1 (en) * 1992-03-24 1993-09-25 Karoly Lempert 2-(substituted imino)-thiazolidines and process for the preparation thereof
EP0600489B1 (en) * 1992-12-04 1996-11-06 Sumitomo Chemical Company Limited Process for producing 2-iminothiazoline derivatives and process for producing their intermediates
US20090156644A1 (en) * 2005-07-21 2009-06-18 Jacob Westman Use of thiazole derivatives and analogues in the treatment of cancer
WO2010086613A1 (en) 2009-01-30 2010-08-05 Betagenon Ab Compounds useful as inhibitors as ampk
BR112015031155A2 (pt) 2013-06-20 2017-07-25 Bayer Cropscience Ag derivados de sulfureto de arila e derivados de aril sulfóxido como acaricidas e inseticidas

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB690238A (en) * 1949-08-23 1953-04-15 Knoll Ag Process of producing 3, 4-dimethyl-5-phenyl-2-iminothiazolidine
DE841149C (de) * 1949-11-01 1952-06-13 Knoll Ag Verfahren zur Herstellung von 3, 4-Dimethyl-5-phenyl-2-iminothiazolidin
DE910650C (de) * 1951-09-14 1954-05-03 Knoll Ag Verfahren zur Herstellung von 2-Amino-í¸ -thiazolinen bzw. Thiazolidon-(2)-imiden undderen Salzen
US3297708A (en) * 1965-10-06 1967-01-10 American Cyanamid Co Method of preparing thiazolidines
FR1510014A (fr) * 1966-12-05 1968-01-19 Aquitaine Petrole Préparation de dithiolannes
SU465792A3 (ru) * 1968-11-06 1975-03-30 Хиноин Гиогисцер-Ес Вегиесцети Термекек Гиара Рт (Фирма) Способ получени гетероциклических соединений
US3671537A (en) * 1969-06-05 1972-06-20 Gyogyszerkutato Intezet Certain 3-(2,6-dichlorophenyl)-2-iminothiazolidines
US3898340A (en) * 1970-04-15 1975-08-05 Bayer Ag Aryliminothiazolidine compositions and methods
CH533420A (de) * 1970-06-23 1973-02-15 Agripat Sa Mittel zur Regulierung des Pflanzenwachstums und zur Erhöhung des Zuckergehaltes in Zuckerrohr
US4029803A (en) * 1976-05-03 1977-06-14 Merck & Co., Inc. Method of treatment with 2-iminothiazolidines and thiazolines
DE2655369A1 (de) * 1976-12-03 1978-06-08 Schering Ag 5-(subst. phenyl)-oxazolidinone und deren schwefelanaloga sowie verfahren zu deren herstellung
HU180240B (en) * 1978-04-21 1983-02-28 Gyogyszerkutato Intezet Process for producing new,substituted 1,3-diaryl-2-iminoimidasolidines and 2-imino-hexahydro-pyrimidines
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones
JPS59227870A (ja) * 1983-06-07 1984-12-21 Yamanouchi Pharmaceut Co Ltd 新規２−グアニジノチアゾリン誘導体ならびにその製造法

Also Published As

Publication number Publication date
FI82454B (fi) 1990-11-30
CS304985A2 (en) 1987-07-16
ES8701741A1 (es) 1986-12-16
SE8501988L (sv) 1985-10-26
US4665083A (en) 1987-05-12
PT80336B (pt) 1987-06-17
GB8510457D0 (en) 1985-05-30
JPH0466478B2 (enExample) 1992-10-23
ES8608499A1 (es) 1986-07-16
PT80336A (en) 1985-05-01
NL8501184A (nl) 1985-11-18
CH664564A5 (de) 1988-03-15
FR2563519A1 (fr) 1985-10-31
FI82454C (fi) 1991-03-11
ATA124285A (de) 1991-10-15
SE464813B (sv) 1991-06-17
GR851006B (enExample) 1985-11-25
PL144821B1 (en) 1988-07-30
DD231790A5 (de) 1986-01-08
FR2563519B1 (fr) 1988-06-10
DK183585D0 (da) 1985-04-24
PL144860B1 (en) 1988-07-30
FI851606A0 (fi) 1985-04-23
IT1208532B (it) 1989-07-10
ES551480A0 (es) 1987-01-16
JPS6127974A (ja) 1986-02-07
NO164417B (no) 1990-06-25
GB2159814B (en) 1987-09-16
NO164417C (no) 1990-10-10
SU1375132A3 (ru) 1988-02-15
IT8520482A0 (it) 1985-04-24
CS255884B2 (en) 1988-03-15
HUT37928A (en) 1986-03-28
ES551481A0 (es) 1986-12-16
PH20995A (en) 1987-06-18
PL253089A1 (en) 1985-12-17
GB2159814A (en) 1985-12-11
AT394555B (de) 1992-05-11
ES542469A0 (es) 1986-07-16
BE902249A (fr) 1985-10-22
SU1549480A3 (ru) 1990-03-07
DE3514843C2 (enExample) 1992-11-05
SE8501988D0 (sv) 1985-04-24
HU191408B (en) 1987-02-27
NO851638L (no) 1985-10-28
DK183585A (da) 1985-10-26
FI851606L (fi) 1985-10-26
SU1366058A3 (ru) 1988-01-07
DE3514843A1 (de) 1985-10-31
ES8702391A1 (es) 1987-01-16
PL145084B1 (en) 1988-08-31

Similar Documents

Publication Publication Date Title
KR930009791B1 (ko) 테트라하이드로-벤즈티아졸의제조방법
CA1311754C (en) Thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same
FR2493320A1 (fr) Nouveaux derives de carbostyrile utiles notamment comme cardiotoniques, leurs procedes de preparation et medicaments les contenant
JPS63243080A (ja) コリン作用系に作用する新規チアゾール誘導体、製造方法および医薬組成物
PT91527A (pt) Processo para a obtencao de derivados de 1,3,4-tiadiazol e de composicoes farmaceuticas que os contem
US20060004062A1 (en) Compounds for inhibiting insulin secretion and methods related thereto
BRPI0713784A2 (pt) compostos orgánicos
DK150502B (da) Analogifremgangsmaade til fremstilling af aminophenylethanolaminer og deres oxazolidiner samt syreadditionssalte deraf
DE69132689T2 (de) Biologisch aktive amine
Wuest et al. Some Derivatives of 3-Pyridol with Parasympathomimetic Properties1
US4665083A (en) Iminothiazolidine derivatives
CN100420678C (zh) 取代的苯并噻唑衍生物的环化方法
US3306903A (en) 1-aminopyridyl-4-(phenyl or pyridyl)-piperazines and intermediates
US3383415A (en) 2-tertiary-aminomethyl-nu-(loweralkyl) anilines
Islip et al. Antiparasitic 5-nitrothiazoles and 5-nitro-4-thiazolines. 4
US4014892A (en) 6-Substituted amino phenyl-2,3,5,6-tetrahydro[2,1-b]thiazoles
US3369022A (en) 3-piperazinoalkyl-2-benzoxazolinones
EP0041630B1 (en) New 3h-naphtho(1,2-d)imidazoles, the process for preparing them, the compounds for use as antiinflammatory agents and compositions containing them
US4711889A (en) Schistosomicidal acridanone hydrazones
US3989835A (en) Method of using 6-substituted amino phenyl-2,3,5,6-tetra-hydro[2,1-b]thiazoles for controlling gastrointestinal nematodes
US3969356A (en) N-[3-(p-f-benzoyl)-propyl]-N'-[2.(nitro,nitro-el, or methoxyphenyl)-ethyl]-p
GB1569238A (en) 2,5-dihdro-1,2-thiazino(5,6-b)indol-3-carboxamide-1,1-dioxide derivatives
US5041462A (en) Novel substituted acetamide compounds and use as anti-allergic agents
SK278791B6 (sk) Izochinolínové deriváty, spôsob ich výroby a farma
DE1470440A1 (de) Verfahren zur herstellung von iminodibenzylderivaten

Legal Events

Date Code Title Description
MKEX Expiry