DE69132689T2 - Biologisch aktive amine - Google Patents
Biologisch aktive amineInfo
- Publication number
- DE69132689T2 DE69132689T2 DE69132689T DE69132689T DE69132689T2 DE 69132689 T2 DE69132689 T2 DE 69132689T2 DE 69132689 T DE69132689 T DE 69132689T DE 69132689 T DE69132689 T DE 69132689T DE 69132689 T2 DE69132689 T2 DE 69132689T2
- Authority
- DE
- Germany
- Prior art keywords
- group
- biologically active
- represent hydrogen
- active amine
- phenylmethyne
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909025176A GB9025176D0 (en) | 1990-11-20 | 1990-11-20 | Compounds |
GB909025178A GB9025178D0 (en) | 1990-11-20 | 1990-11-20 | Compounds |
GB909025180A GB9025180D0 (en) | 1990-11-20 | 1990-11-20 | Compounds |
PCT/GB1991/002042 WO1992008708A1 (en) | 1990-11-20 | 1991-11-19 | Biologically active amines |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69132689D1 DE69132689D1 (de) | 2001-09-20 |
DE69132689T2 true DE69132689T2 (de) | 2002-06-27 |
Family
ID=27265379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69132689T Expired - Fee Related DE69132689T2 (de) | 1990-11-20 | 1991-11-19 | Biologisch aktive amine |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0558677B1 (de) |
JP (2) | JPH06502635A (de) |
AT (1) | ATE204263T1 (de) |
AU (1) | AU8912891A (de) |
DE (1) | DE69132689T2 (de) |
DK (1) | DK0558677T3 (de) |
ES (1) | ES2163396T3 (de) |
IE (1) | IE914003A1 (de) |
PT (1) | PT99563B (de) |
SG (1) | SG47947A1 (de) |
WO (1) | WO1992008708A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9211172D0 (en) * | 1992-05-27 | 1992-07-08 | Fisons Plc | Compounds |
GB9210632D0 (en) * | 1992-05-19 | 1992-07-01 | Fisons Plc | Compounds |
TW356468B (en) * | 1995-09-15 | 1999-04-21 | Astra Pharma Prod | Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same |
GB9526511D0 (en) * | 1995-12-23 | 1996-02-28 | Astra Pharma Prod | Pharmaceutically active compounds |
US5990144A (en) * | 1997-02-18 | 1999-11-23 | American Home Products Corporation | 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists |
BR9807703A (pt) * | 1997-02-18 | 2000-05-02 | American Home Prod | Derivados de 4-aminoalcóxi-1,3-diidrobenzoimidazol-2-ona, suas preparações e seus usos como agonistas (d2) auto-receptores da dopamina |
TW200508197A (en) * | 2003-03-31 | 2005-03-01 | Ucb Sa | Indolone-acetamide derivatives, processes for preparing them and their uses |
CN100569760C (zh) | 2003-11-21 | 2009-12-16 | 施万制药 | 具有β2肾上腺素能受体激动剂和毒蕈碱性受体拮抗剂活性的化合物 |
TW200738658A (en) | 2005-08-09 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
TW200745067A (en) | 2006-03-14 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
TW200833670A (en) | 2006-12-20 | 2008-08-16 | Astrazeneca Ab | Novel compounds 569 |
GB0702458D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 668 |
GB0704000D0 (en) * | 2007-03-01 | 2007-04-11 | Astrazeneca Ab | Salts 670 |
UY31905A (es) | 2008-06-18 | 2010-01-29 | Astrazeneca Ab | Derivados de benzoxazinona, procesos de preparación, composiciones farmacéuticas conteniéndolos y aplicaciones. |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4314944A (en) * | 1980-08-22 | 1982-02-09 | Smithkline Corporation | 4-Aminoalkyl-7-hydroxy-2(3H)-indolones |
US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
GB8426200D0 (en) * | 1984-10-17 | 1984-11-21 | Glaxo Holdings Ltd | Chemical compounds |
US4554284A (en) * | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones |
US4554287A (en) * | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones |
DK514585A (da) * | 1984-11-08 | 1986-05-09 | Syntex Inc | Aminoethylanilinderivater |
DE3728695A1 (de) * | 1987-08-25 | 1989-03-09 | Schering Ag | Neue benzimidazol-derivate |
-
1991
- 1991-11-18 IE IE400391A patent/IE914003A1/en not_active Application Discontinuation
- 1991-11-19 SG SG1996005606A patent/SG47947A1/en unknown
- 1991-11-19 ES ES92902511T patent/ES2163396T3/es not_active Expired - Lifetime
- 1991-11-19 WO PCT/GB1991/002042 patent/WO1992008708A1/en active IP Right Grant
- 1991-11-19 DE DE69132689T patent/DE69132689T2/de not_active Expired - Fee Related
- 1991-11-19 AU AU89128/91A patent/AU8912891A/en not_active Abandoned
- 1991-11-19 DK DK92902511T patent/DK0558677T3/da active
- 1991-11-19 JP JP4500435A patent/JPH06502635A/ja active Pending
- 1991-11-19 AT AT92902511T patent/ATE204263T1/de not_active IP Right Cessation
- 1991-11-19 EP EP92902511A patent/EP0558677B1/de not_active Expired - Lifetime
- 1991-11-20 PT PT99563A patent/PT99563B/pt active IP Right Grant
-
2000
- 2000-03-07 JP JP2000061374A patent/JP2000290240A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
SG47947A1 (en) | 1998-04-17 |
WO1992008708A1 (en) | 1992-05-29 |
PT99563B (pt) | 1999-04-30 |
PT99563A (pt) | 1992-10-30 |
EP0558677A1 (de) | 1993-09-08 |
JP2000290240A (ja) | 2000-10-17 |
DE69132689D1 (de) | 2001-09-20 |
ES2163396T3 (es) | 2002-02-01 |
IE914003A1 (en) | 1992-05-20 |
JPH06502635A (ja) | 1994-03-24 |
EP0558677B1 (de) | 2001-08-16 |
AU8912891A (en) | 1992-06-11 |
DK0558677T3 (da) | 2001-11-12 |
ATE204263T1 (de) | 2001-09-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3365772D1 (en) | 1,4-dihydropyridines, process for their preparation and their application as pharmaceutical preparations | |
ATE204263T1 (de) | Biologisch aktive amine | |
ATE124405T1 (de) | 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel. | |
NO996108L (no) | 9-oksinerytromycinderivater | |
AR007828A1 (es) | Compuestos derivados de piridilpirrol, procedimiento de preparacion y composiciones farmaceuticas conteniendo los mismos | |
EA200100983A1 (ru) | Производные 13-метилэритромицина | |
FI943142A0 (fi) | Amidi- ja ureajohdannaiset, joilla on veren korkeita kolesteroliarvoja vastustava vaikutus, niiden valmistus ja terapeuttiset käytöt | |
DK0734383T3 (da) | Cykliske amidderivater som neurokinin-A-antagonister | |
DZ1694A1 (fr) | "n-(2-Aminoethyl)-benzothialozones". | |
DE69429591T2 (de) | Therapeutisch wirksame Verbindungen | |
ES2160602T3 (es) | Derivados de quinolona y acridinona para el tratamiento de la incontinencia urinaria. | |
PT992509E (pt) | Novos derivados macrolidos | |
ATE170852T1 (de) | Benzolsulfonamid-derivate zur behandlung der blaseninstabilität | |
DE59409595D1 (de) | Anellierte dihydropyridine und deren verwendung für die herstellung von pharmazeutischen zubereitungen | |
MX9804828A (es) | Benzotiazolona etanaminas biologicamente activas. | |
DE3564684D1 (en) | Tetrahydrothienopyridines, process for their preparation and their pharmaceutical application | |
PT861250E (pt) | Derivados de amidina e de isotioureia como inibidores de oxido nitrico sintase | |
DE69330601T2 (de) | Serotoninergische ergolin derivate | |
BR8400549A (pt) | Derivados e sais inertes de hidroxido de aminopiridinios e processos de preparacao;e composicao farmaceutica | |
ATE247955T1 (de) | Selenophen-antitumormittel | |
DK0556813T3 (da) | Amfotere tricykliske forbindelser som antihistaminske og antiallergiske midler | |
ATE144510T1 (de) | N-(isochinolein-5-yl)-sulfonyl azazykloalkane, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen | |
PT782574E (pt) | Carboxamidas biciclicas como antagonistas 5-ht1a | |
IT1241927B (it) | 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono | |
ATE279434T1 (de) | Neue (3,4,7,8,9,10) hexahydro-6, 10-dioxo-6h- pyridazino /1, 2-a/ /1, 2/ diazepin-1-carbonsäure-derivate, verfahren zu deren herstellung und deren verwendung zur herstellung pharmazeutischer wirkstoffe |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |