CA1198105A - Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle - Google Patents

Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle

Info

Publication number
CA1198105A
CA1198105A CA000375784A CA375784A CA1198105A CA 1198105 A CA1198105 A CA 1198105A CA 000375784 A CA000375784 A CA 000375784A CA 375784 A CA375784 A CA 375784A CA 1198105 A CA1198105 A CA 1198105A
Authority
CA
Canada
Prior art keywords
antiinflammatory
compounds
atoms
deoxy
active principle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000375784A
Other languages
English (en)
French (fr)
Inventor
Giorgio Stramentinoli
Frederico Gennari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
Bioresearch SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch SRL filed Critical Bioresearch SRL
Priority to CA000490761A priority Critical patent/CA1209915A/en
Application granted granted Critical
Publication of CA1198105A publication Critical patent/CA1198105A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000375784A 1980-04-22 1981-04-21 Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle Expired CA1198105A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000490761A CA1209915A (en) 1980-04-22 1985-09-13 Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo
ITN.21550A/80 1980-04-22

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000490761A Division CA1209915A (en) 1980-04-22 1985-09-13 Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle

Publications (1)

Publication Number Publication Date
CA1198105A true CA1198105A (en) 1985-12-17

Family

ID=11183457

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000375784A Expired CA1198105A (en) 1980-04-22 1981-04-21 Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle

Country Status (17)

Country Link
JP (2) JPS56166117A (US20020051482A1-20020502-M00012.png)
AR (1) AR231144A1 (US20020051482A1-20020502-M00012.png)
BE (1) BE888472A (US20020051482A1-20020502-M00012.png)
CA (1) CA1198105A (US20020051482A1-20020502-M00012.png)
CH (2) CH645544A5 (US20020051482A1-20020502-M00012.png)
DE (1) DE3116067A1 (US20020051482A1-20020502-M00012.png)
DK (1) DK159453C (US20020051482A1-20020502-M00012.png)
ES (2) ES501539A0 (US20020051482A1-20020502-M00012.png)
FI (1) FI70227C (US20020051482A1-20020502-M00012.png)
FR (1) FR2491761A1 (US20020051482A1-20020502-M00012.png)
GB (3) GB2074446B (US20020051482A1-20020502-M00012.png)
IT (1) IT1193529B (US20020051482A1-20020502-M00012.png)
LU (1) LU83307A1 (US20020051482A1-20020502-M00012.png)
MX (1) MX9203630A (US20020051482A1-20020502-M00012.png)
NL (1) NL192111C (US20020051482A1-20020502-M00012.png)
NO (1) NO150515C (US20020051482A1-20020502-M00012.png)
SE (3) SE460198B (US20020051482A1-20020502-M00012.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (it) * 1984-12-06 1987-08-26 Bioresearch Spa Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica
IT1227049B (it) * 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
JPH0497287A (ja) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd 画像表示集積回路
ES2259552B1 (es) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
RS51122B (sr) * 2005-03-17 2010-10-31 Proyecto De Biomedicina Cima S.L. Primena 5`-metiltioadenozina(mta) kod prevencije i/ili lečenja autoimunih bolesti i/ili pri odbacivanju transplantata
DE102010027595A1 (de) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Vermeidung von Ischämie- oder Degenerations-Schäden im Gehirn bei Anwendung von Adenosin-Derivaten
DE102011005232A1 (de) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosin und seine Derivate zur Verwendung in der Schmerztherapie
WO2014163152A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 ノンレム睡眠促進剤、深睡眠促進剤および自然睡眠誘発剤
WO2014163151A1 (ja) * 2013-04-05 2014-10-09 ライオン株式会社 酵母培養物及び内服組成物
KR102245628B1 (ko) * 2013-04-05 2021-04-28 라이온 가부시키가이샤 내복 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (de) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 5'-Sulfoxyde von Nucleosiden
DE1545645A1 (de) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Verfahren zur Herstellung von disubstituierten Adenosin-Derivaten
FR2252405B1 (US20020051482A1-20020502-M00012.png) * 1973-11-27 1978-04-28 Ajinomoto Kk
FR2313937A1 (fr) * 1975-06-09 1977-01-07 Anvar Medicament a base de 5' thioethers de l'adenosine
FR2424027A1 (fr) * 1978-04-28 1979-11-23 Merieux Inst Nouveau medicament, notamment sedatif et inducteur de sommeil et compositions pharmaceutiques la renfermant

Also Published As

Publication number Publication date
GB2144409B (en) 1985-09-11
JPH0246599B2 (US20020051482A1-20020502-M00012.png) 1990-10-16
FR2491761B1 (US20020051482A1-20020502-M00012.png) 1984-01-06
GB8321947D0 (en) 1983-09-14
SE466238B (sv) 1992-01-20
CH650514A5 (de) 1985-07-31
ES8206551A1 (es) 1982-08-16
JPS56166117A (en) 1981-12-21
NO811346L (no) 1981-10-23
NO150515B (no) 1984-07-23
SE8700914D0 (sv) 1987-03-04
IT1193529B (it) 1988-07-08
NL192111B (nl) 1996-10-01
GB2144038A (en) 1985-02-27
SE8700913L (sv) 1987-03-04
DE3116067C2 (US20020051482A1-20020502-M00012.png) 1992-12-17
DK159453C (da) 1991-03-18
JPH01301692A (ja) 1989-12-05
SE8700914L (sv) 1987-03-04
GB2074446A (en) 1981-11-04
FI70227C (fi) 1986-09-15
NL8101984A (nl) 1981-11-16
IT8021550A0 (it) 1980-04-22
SE8102489L (sv) 1981-10-23
SE464635B (sv) 1991-05-27
GB8413454D0 (en) 1984-07-04
FR2491761A1 (fr) 1982-04-16
SE8700913D0 (sv) 1987-03-04
SE460198B (sv) 1989-09-18
ES501539A0 (es) 1982-08-16
DE3116067A1 (de) 1982-03-11
BE888472A (fr) 1981-08-17
GB2074446B (en) 1985-04-11
AR231144A1 (es) 1984-09-28
ES511039A0 (es) 1983-06-01
DK159453B (da) 1990-10-15
CH645544A5 (de) 1984-10-15
ES8306378A1 (es) 1983-06-01
LU83307A1 (fr) 1981-07-24
GB2144409A (en) 1985-03-06
NL192111C (nl) 1997-02-04
DK176481A (da) 1981-10-23
JPH0249288B2 (US20020051482A1-20020502-M00012.png) 1990-10-29
MX9203630A (es) 1992-09-01
FI70227B (fi) 1986-02-28
NO150515C (no) 1984-10-31
GB2144038B (en) 1985-08-29
FI811249L (fi) 1981-10-23

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Legal Events

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