CA1101333A - Procede de fabrication d'un concentre proteique contenant des facteurs immunologiques d'origine lactique - Google Patents
Procede de fabrication d'un concentre proteique contenant des facteurs immunologiques d'origine lactiqueInfo
- Publication number
- CA1101333A CA1101333A CA300,770A CA300770A CA1101333A CA 1101333 A CA1101333 A CA 1101333A CA 300770 A CA300770 A CA 300770A CA 1101333 A CA1101333 A CA 1101333A
- Authority
- CA
- Canada
- Prior art keywords
- milk
- immunoglobulins
- whey
- bacteria
- casein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000012141 concentrate Substances 0.000 title claims abstract description 33
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 21
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 20
- 229940088592 immunologic factor Drugs 0.000 title claims abstract 3
- 239000000367 immunologic factor Substances 0.000 title claims abstract 3
- 238000002360 preparation method Methods 0.000 title description 3
- 235000013336 milk Nutrition 0.000 claims abstract description 43
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- 238000000034 method Methods 0.000 claims abstract description 30
- 241000588724 Escherichia coli Species 0.000 claims abstract description 21
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- 239000005018 casein Substances 0.000 claims abstract description 16
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims abstract description 15
- 235000021240 caseins Nutrition 0.000 claims abstract description 15
- 239000006071 cream Substances 0.000 claims abstract description 14
- 230000008569 process Effects 0.000 claims abstract description 12
- 238000001914 filtration Methods 0.000 claims abstract description 11
- 108060003951 Immunoglobulin Proteins 0.000 claims abstract description 10
- 102000018358 immunoglobulin Human genes 0.000 claims abstract description 10
- 229940072221 immunoglobulins Drugs 0.000 claims abstract description 10
- 235000020183 skimmed milk Nutrition 0.000 claims abstract description 7
- 238000004519 manufacturing process Methods 0.000 claims abstract description 6
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- 229960005486 vaccine Drugs 0.000 claims description 28
- 241000283690 Bos taurus Species 0.000 claims description 20
- 108010046377 Whey Proteins Proteins 0.000 claims description 17
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- 102000007544 Whey Proteins Human genes 0.000 claims description 13
- 235000021119 whey protein Nutrition 0.000 claims description 9
- 239000005862 Whey Substances 0.000 claims description 8
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- 238000000926 separation method Methods 0.000 claims description 8
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- 230000015271 coagulation Effects 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 7
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 6
- 239000000427 antigen Substances 0.000 claims description 6
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- 108091007433 antigens Proteins 0.000 claims description 6
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 10
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- 238000007792 addition Methods 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
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- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 4
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- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 3
- 241000699666 Mus <mouse, genus> Species 0.000 description 3
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- 239000004202 carbamide Substances 0.000 description 3
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 3
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 2
- 241000237074 Centris Species 0.000 description 2
- 208000003098 Ganglion Cysts Diseases 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 102000008192 Lactoglobulins Human genes 0.000 description 2
- 108010060630 Lactoglobulins Proteins 0.000 description 2
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- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 2
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- 235000011130 ammonium sulphate Nutrition 0.000 description 2
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- DGQLVPJVXFOQEV-JNVSTXMASA-N carminic acid Chemical compound OC1=C2C(=O)C=3C(C)=C(C(O)=O)C(O)=CC=3C(=O)C2=C(O)C(O)=C1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O DGQLVPJVXFOQEV-JNVSTXMASA-N 0.000 description 2
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- 101710186708 Agglutinin Proteins 0.000 description 1
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- 102000009027 Albumins Human genes 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- PWNAWOCHVWERAR-UHFFFAOYSA-N Flumetralin Chemical compound [O-][N+](=O)C=1C=C(C(F)(F)F)C=C([N+]([O-])=O)C=1N(CC)CC1=C(F)C=CC=C1Cl PWNAWOCHVWERAR-UHFFFAOYSA-N 0.000 description 1
- 102000006395 Globulins Human genes 0.000 description 1
- 108010044091 Globulins Proteins 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 101710146024 Horcolin Proteins 0.000 description 1
- 239000007836 KH2PO4 Substances 0.000 description 1
- 102000010445 Lactoferrin Human genes 0.000 description 1
- 108010063045 Lactoferrin Proteins 0.000 description 1
- 108010023244 Lactoperoxidase Proteins 0.000 description 1
- 102000045576 Lactoperoxidases Human genes 0.000 description 1
- 101710189395 Lectin Proteins 0.000 description 1
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- RSPISYXLHRIGJD-UHFFFAOYSA-N OOOO Chemical compound OOOO RSPISYXLHRIGJD-UHFFFAOYSA-N 0.000 description 1
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- 230000004520 agglutination Effects 0.000 description 1
- 239000000910 agglutinin Substances 0.000 description 1
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- 239000001166 ammonium sulphate Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
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- 244000052616 bacterial pathogen Species 0.000 description 1
- 229940125717 barbiturate Drugs 0.000 description 1
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
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- XLYOFNOQVPJJNP-ZSJDYOACSA-N heavy water Substances [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
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- 229910052742 iron Inorganic materials 0.000 description 1
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 description 1
- 235000021242 lactoferrin Nutrition 0.000 description 1
- 229940078795 lactoferrin Drugs 0.000 description 1
- 229940057428 lactoperoxidase Drugs 0.000 description 1
- 210000004324 lymphatic system Anatomy 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000013028 medium composition Substances 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 230000014207 opsonization Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 230000017854 proteolysis Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 229940108461 rennet Drugs 0.000 description 1
- 108010058314 rennet Proteins 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 208000026775 severe diarrhea Diseases 0.000 description 1
- MHQHHBYRYFICDV-UHFFFAOYSA-M sodium;pyrimidin-3-ide-2,4,6-trione Chemical compound [Na+].O=C1CC(=O)[N-]C(=O)N1 MHQHHBYRYFICDV-UHFFFAOYSA-M 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
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- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
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- 239000011782 vitamin Substances 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/04—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
- A23J1/205—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey from whey, e.g. lactalbumine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Dairy Products (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH4679/77 | 1977-04-15 | ||
| CH467977A CH627079A5 (en) | 1977-04-15 | 1977-04-15 | Process for preparing a protein concentrate containing immunological factors of milk origin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1101333A true CA1101333A (fr) | 1981-05-19 |
Family
ID=4280585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA300,770A Expired CA1101333A (fr) | 1977-04-15 | 1978-04-10 | Procede de fabrication d'un concentre proteique contenant des facteurs immunologiques d'origine lactique |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS53130411A (es) |
| AR (1) | AR218482A1 (es) |
| AU (1) | AU519091B2 (es) |
| CA (1) | CA1101333A (es) |
| CH (1) | CH627079A5 (es) |
| DE (1) | DE2813984A1 (es) |
| DK (1) | DK153521C (es) |
| ES (1) | ES468808A1 (es) |
| FR (1) | FR2387039A1 (es) |
| GB (1) | GB1573995A (es) |
| GR (1) | GR64433B (es) |
| IT (1) | IT1156193B (es) |
| MX (1) | MX5007E (es) |
| MY (1) | MY8100294A (es) |
| NL (1) | NL187516C (es) |
| OA (1) | OA05938A (es) |
| PH (2) | PH14031A (es) |
| SE (1) | SE448062B (es) |
| ZA (1) | ZA781607B (es) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9943597B2 (en) | 2010-08-17 | 2018-04-17 | Immuron Limited | Anti-LPS enriched immunoglobulin preparation for use in treatment and/or prophylaxis of a pathologic disorder |
| US10117930B2 (en) | 2009-04-27 | 2018-11-06 | Immuron Limited | Anti-LPS enriched immunoglobulin preparations for the treatment and/or prophylaxis of a pathologic disorder |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE448344B (sv) * | 1978-02-06 | 1987-02-16 | Stolle Res & Dev | Antikropp for behandling av reumatoid artrit samt sett att framstella denna |
| FR2460135A1 (fr) * | 1979-07-02 | 1981-01-23 | Liotet Serge | Composition a usage externe a base de colostrum |
| EP0064103B1 (en) * | 1981-04-28 | 1985-11-06 | The Stolle Research And Development Corporation | Method of obtaining an anti-inflammatory bovine milk |
| JP2561234B2 (ja) * | 1981-05-12 | 1996-12-04 | スト−ル・リサ−チ・アンド・デイベロップメント・コ−ポレ−ション | 抗炎症剤 |
| JPS58154513A (ja) * | 1982-03-09 | 1983-09-14 | Sendai Biseibutsu Kenkyusho | 予防及び治療薬 |
| NZ205392A (en) * | 1982-09-02 | 1987-03-06 | Unilever Plc | Preparation of immunoglobulins against e.coli pili |
| JPS6112629A (ja) * | 1984-06-28 | 1986-01-21 | Lion Corp | 口腔内組成物 |
| DE3432718C1 (de) * | 1984-09-06 | 1986-05-22 | Biotest Pharma GmbH, 6000 Frankfurt | Verfahren zur Herstellung einer Loesung von Milch- und/oder Kolostralimmunglobulinen |
| US4834974A (en) * | 1986-01-13 | 1989-05-30 | Protein Technologies, Inc. | Immunologically active whey fraction and recovery process |
| US4816252A (en) * | 1985-04-15 | 1989-03-28 | Protein Technology, Inc. | Product and process for transferring passive immunity to newborn domestic animals using ultrafiltered whey containing immunoglobulins |
| GB8729031D0 (en) * | 1987-12-11 | 1988-01-27 | Express Foods Group Ltd | Isolation of immunoglobulin rich fraction from whey |
| IE76730B1 (en) * | 1990-07-30 | 1997-11-05 | Abbott Laboraties | Method and product for the treatment of gastric disease |
| US5258178A (en) * | 1990-07-30 | 1993-11-02 | Abbott Laboratories | Method and product for the treatment of gastric disease |
| DE4026365A1 (de) * | 1990-08-21 | 1992-02-27 | Biotest Pharma Gmbh | Sterilfiltrierte kolostralmilch |
| JPH04169539A (ja) * | 1990-11-01 | 1992-06-17 | Imuno Japan:Kk | 消化器疾患治療・予防剤およびその製造方法 |
| US5645834A (en) * | 1992-08-28 | 1997-07-08 | Immuno-Dynamics, Inc. | Method and product for treating failure of passive transfer and improving milk production in bovine species |
| DE69432309D1 (de) * | 1993-09-20 | 2003-04-24 | Anadis Ltd | Verfahren zur herstellung von immunoglobulinen aus colostrum und deren verwendung in pharmazeutischen zusammensetzungen |
| FI97269B (fi) * | 1993-10-12 | 1996-08-15 | Viable Bioproducts Ltd | Menetelmä ravintojuoman valmistamiseksi |
| ZA949789B (en) * | 1993-12-30 | 1995-10-25 | Immunotec Res Corp Ltd | Process for making undenatured whey protein concentrate |
| US5707678A (en) * | 1995-04-12 | 1998-01-13 | Galagen Inc. | Method for microfiltration of milk or colostral whey |
| US5670196A (en) * | 1995-04-12 | 1997-09-23 | Galagen Inc. | Method for microfiltration of milk or colostral whey |
| CA2165937A1 (en) * | 1995-05-09 | 1996-11-10 | Immunotec Research Corporation Ltd. | Process for producing an undenatured whey protein concentrate |
| AUPN642795A0 (en) * | 1995-11-08 | 1995-11-30 | Northfield Laboratories Pty Ltd | Dairy compositions and methods of preparing same |
| US5772999A (en) * | 1996-07-30 | 1998-06-30 | Dcv Biologics, L.P. | Method of preventing, countering, or reducing NSAID-induced gastrointestinal damage by administering milk or egg products from hyperimmunized animals |
| AU738888B2 (en) * | 1997-05-29 | 2001-09-27 | Agresearch Limited | Processes for production of immunoglobulin A in milk |
| IE970541A1 (en) † | 1997-07-25 | 1999-01-27 | Michael Anthony Folan | Maternal immune secretions and their use in the treatment and/or prophylaxis of the buccal cavity |
| FI110752B (fi) | 1999-05-25 | 2003-03-31 | Novatreat Oy | Menetelmä ternimaidon käsittelemiseksi |
| SE0003045D0 (sv) * | 2000-08-29 | 2000-08-29 | Probi Ab | New method |
| DK1435786T3 (da) | 2001-09-17 | 2011-10-03 | Lilly Co Eli | Pesticide formuleringer |
| DE10158009A1 (de) | 2001-11-21 | 2003-05-28 | Begerow E Gmbh & Co | Verfahren zur Reduzierung der Gesamtkeimzahl in wäßrigen Dispersionen |
| DE602004006258T3 (de) | 2004-08-24 | 2013-08-29 | Nutricia N.V. | Nahrungszusammensetzung die unverdauliche Transgalaktooligosaccharide sowie verdauliche Galaktose-Saccharide enthält |
| NL1033696C2 (nl) * | 2007-04-16 | 2008-10-20 | Friesland Brands Bv | Aan melk ontleende antigeen-specifieke antilichamen, werkwijzen voor het bereiden en gebruik ervan. |
| US8475789B2 (en) | 2008-01-22 | 2013-07-02 | Multimerics Aps | Products and methods to prevent infections |
| RU2010151414A (ru) * | 2008-05-15 | 2012-06-20 | В.Хэлт Л.П. (Bs) | Способ получения фракций молока, обогащенных секреторными иммуноглобулинами |
| US10278404B2 (en) * | 2012-09-11 | 2019-05-07 | Al-Urdonia Lemudaddat Al-Ajsam Co | Immunized camel milk-based composition for the treatment or prevention of gastrointestinal infections |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE546837A (es) * | ||||
| DE1022356B (de) * | 1955-04-07 | 1958-01-09 | Berry Campbell | Verfahren zur Herstellung eines spezifischen Schutzstoffes gegen ein Antigen |
| DK87610C (da) * | 1955-04-07 | 1959-07-27 | Berry Campbell | Fremgangsmåde til fremstilling af specifikke beskyttelsesstoffer mod antigene stoffer. |
| FR1599671A (es) * | 1966-06-27 | 1970-07-20 | ||
| GB1211876A (en) * | 1967-11-23 | 1970-11-11 | Twyford Lab Ltd | Improvements in and relating to prophylactic and therapeutic preparations |
| NL7011786A (es) * | 1969-09-24 | 1971-03-26 | ||
| US3930039A (en) * | 1971-07-30 | 1975-12-30 | Molkerei J A Meggle Milchindus | Method of preparing a protein concentrate from whey |
| BE788120A (fr) * | 1971-09-01 | 1973-02-28 | Coca Cola Co | Traitement des proteines du petit-lait |
| US3911108A (en) * | 1973-02-14 | 1975-10-07 | Diamond Shamrock Corp | Process of producing bovine milk products containing specific antibodies |
-
1977
- 1977-04-15 CH CH467977A patent/CH627079A5/fr not_active IP Right Cessation
-
1978
- 1978-03-20 ZA ZA00781607A patent/ZA781607B/xx unknown
- 1978-03-21 GB GB11106/78A patent/GB1573995A/en not_active Expired
- 1978-03-22 DK DK131078A patent/DK153521C/da not_active IP Right Cessation
- 1978-03-24 FR FR7808705A patent/FR2387039A1/fr active Granted
- 1978-03-31 DE DE19782813984 patent/DE2813984A1/de active Granted
- 1978-04-03 MX MX786992U patent/MX5007E/es unknown
- 1978-04-06 AR AR271715A patent/AR218482A1/es active
- 1978-04-10 AU AU34903/78A patent/AU519091B2/en not_active Expired
- 1978-04-10 CA CA300,770A patent/CA1101333A/fr not_active Expired
- 1978-04-11 PH PH20991A patent/PH14031A/en unknown
- 1978-04-13 SE SE7804190A patent/SE448062B/sv not_active IP Right Cessation
- 1978-04-14 NL NLAANVRAGE7804015,A patent/NL187516C/xx not_active IP Right Cessation
- 1978-04-14 JP JP4409378A patent/JPS53130411A/ja active Granted
- 1978-04-14 ES ES468808A patent/ES468808A1/es not_active Expired
- 1978-04-14 IT IT48896/78A patent/IT1156193B/it active
- 1978-04-14 OA OA56468A patent/OA05938A/xx unknown
- 1978-04-14 GR GR55978A patent/GR64433B/el unknown
-
1979
- 1979-01-29 PH PH22133A patent/PH17782A/en unknown
-
1981
- 1981-12-30 MY MY294/81A patent/MY8100294A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10117930B2 (en) | 2009-04-27 | 2018-11-06 | Immuron Limited | Anti-LPS enriched immunoglobulin preparations for the treatment and/or prophylaxis of a pathologic disorder |
| US9943597B2 (en) | 2010-08-17 | 2018-04-17 | Immuron Limited | Anti-LPS enriched immunoglobulin preparation for use in treatment and/or prophylaxis of a pathologic disorder |
Also Published As
| Publication number | Publication date |
|---|---|
| CH627079A5 (en) | 1981-12-31 |
| DE2813984C2 (es) | 1987-11-26 |
| PH17782A (en) | 1984-12-11 |
| GR64433B (en) | 1980-03-21 |
| DK153521C (da) | 1988-12-05 |
| SE448062B (sv) | 1987-01-19 |
| OA05938A (fr) | 1981-06-30 |
| FR2387039B1 (es) | 1981-07-24 |
| ES468808A1 (es) | 1978-12-01 |
| MX5007E (es) | 1983-02-14 |
| GB1573995A (en) | 1980-09-03 |
| JPS53130411A (en) | 1978-11-14 |
| AU519091B2 (en) | 1981-11-05 |
| IT1156193B (it) | 1987-01-28 |
| AR218482A1 (es) | 1980-06-13 |
| PH14031A (en) | 1980-12-12 |
| SE7804190L (sv) | 1978-10-16 |
| NL187516B (nl) | 1991-06-03 |
| MY8100294A (en) | 1981-12-31 |
| JPS6340771B2 (es) | 1988-08-12 |
| AU3490378A (en) | 1979-10-18 |
| DE2813984A1 (de) | 1978-10-26 |
| IT7848896A0 (it) | 1978-04-14 |
| DK131078A (da) | 1978-10-16 |
| NL187516C (nl) | 1991-11-01 |
| DK153521B (da) | 1988-07-25 |
| FR2387039A1 (fr) | 1978-11-10 |
| NL7804015A (nl) | 1978-10-17 |
| ZA781607B (en) | 1979-03-28 |
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