BRPI0913397B8 - método para preparar plasmina - Google Patents

método para preparar plasmina

Info

Publication number
BRPI0913397B8
BRPI0913397B8 BRPI0913397A BRPI0913397A BRPI0913397B8 BR PI0913397 B8 BRPI0913397 B8 BR PI0913397B8 BR PI0913397 A BRPI0913397 A BR PI0913397A BR PI0913397 A BRPI0913397 A BR PI0913397A BR PI0913397 B8 BRPI0913397 B8 BR PI0913397B8
Authority
BR
Brazil
Prior art keywords
plasmin
preparing
immobilized
streptokinase
preparing plasmin
Prior art date
Application number
BRPI0913397A
Other languages
English (en)
Portuguese (pt)
Inventor
Koepf Edward
P Zimmerman Thomas
Original Assignee
Grifols Therapeutics Inc
Talecris Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols Therapeutics Inc, Talecris Biotherapeutics Inc filed Critical Grifols Therapeutics Inc
Publication of BRPI0913397A2 publication Critical patent/BRPI0913397A2/pt
Publication of BRPI0913397B1 publication Critical patent/BRPI0913397B1/pt
Publication of BRPI0913397B8 publication Critical patent/BRPI0913397B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153—Streptokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24029—Aureolysin (3.4.24.29)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
BRPI0913397A 2008-06-04 2009-06-03 método para preparar plasmina BRPI0913397B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5867708P 2008-06-04 2008-06-04
PCT/US2009/046152 WO2009149199A2 (fr) 2008-06-04 2009-06-03 Composition, méthode et nécessaire pour la préparation de plasmine

Publications (3)

Publication Number Publication Date
BRPI0913397A2 BRPI0913397A2 (pt) 2015-08-04
BRPI0913397B1 BRPI0913397B1 (pt) 2020-02-04
BRPI0913397B8 true BRPI0913397B8 (pt) 2021-05-25

Family

ID=41398848

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0913397A BRPI0913397B8 (pt) 2008-06-04 2009-06-03 método para preparar plasmina

Country Status (15)

Country Link
US (1) US8617863B2 (fr)
EP (1) EP2297317A4 (fr)
JP (1) JP2011522538A (fr)
KR (2) KR20160110544A (fr)
CN (1) CN102057044B (fr)
AU (1) AU2009256168B2 (fr)
BR (1) BRPI0913397B8 (fr)
CA (1) CA2726908C (fr)
IL (1) IL209511A (fr)
MX (1) MX2010013282A (fr)
NZ (1) NZ589557A (fr)
RU (1) RU2497948C2 (fr)
UA (1) UA103771C2 (fr)
WO (1) WO2009149199A2 (fr)
ZA (1) ZA201008564B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102234332B (zh) * 2010-04-26 2014-12-17 浙江海正药业股份有限公司 一种重组人血白蛋白及其融合蛋白的分离纯化工艺
FR3034992A1 (fr) * 2015-04-15 2016-10-21 Arcadophta Milieu plasmatique ex vivo autologue riche en plasmine et procede d'obtention
FR3035120B1 (fr) * 2015-04-15 2020-02-07 Arcadophta Composition de plasminogenase immobilisee, procede de preparation, utilisation et dispositif comprenant une telle composition

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Also Published As

Publication number Publication date
US8617863B2 (en) 2013-12-31
WO2009149199A3 (fr) 2010-04-01
NZ589557A (en) 2012-08-31
BRPI0913397B1 (pt) 2020-02-04
BRPI0913397A2 (pt) 2015-08-04
US20110201077A1 (en) 2011-08-18
KR20160110544A (ko) 2016-09-21
CA2726908A1 (fr) 2009-12-10
CA2726908C (fr) 2017-01-24
IL209511A (en) 2015-07-30
ZA201008564B (en) 2011-07-27
AU2009256168B2 (en) 2014-06-05
AU2009256168A1 (en) 2009-12-10
CN102057044B (zh) 2013-05-01
KR20110017903A (ko) 2011-02-22
EP2297317A2 (fr) 2011-03-23
MX2010013282A (es) 2010-12-21
RU2010154401A (ru) 2012-07-20
JP2011522538A (ja) 2011-08-04
EP2297317A4 (fr) 2011-12-07
UA103771C2 (ru) 2013-11-25
IL209511A0 (en) 2011-01-31
CN102057044A (zh) 2011-05-11
WO2009149199A2 (fr) 2009-12-10
RU2497948C2 (ru) 2013-11-10

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