DK98833C - Fremgangsmåde til stabilisering af terapeutisk anvendelige plasminopløsninger. - Google Patents

Fremgangsmåde til stabilisering af terapeutisk anvendelige plasminopløsninger.

Info

Publication number
DK98833C
DK98833C DK169161AA DK169161A DK98833C DK 98833 C DK98833 C DK 98833C DK 169161A A DK169161A A DK 169161AA DK 169161 A DK169161 A DK 169161A DK 98833 C DK98833 C DK 98833C
Authority
DK
Denmark
Prior art keywords
stabilizing
therapeutically useful
plasmin
solutions
plasmin solutions
Prior art date
Application number
DK169161AA
Other languages
English (en)
Inventor
Johannes Jensen
Original Assignee
Novo Terapeutisk Labor As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Terapeutisk Labor As filed Critical Novo Terapeutisk Labor As
Priority to DK169161AA priority Critical patent/DK98833C/da
Priority to NO144057A priority patent/NO123024B/no
Priority to SE04365/62A priority patent/SE327779B/xx
Priority to GB15352/62A priority patent/GB985498A/en
Priority to BE616779A priority patent/BE616779A/fr
Priority to NL62277635A priority patent/NL147634B/xx
Priority to CH497562A priority patent/CH456848A/fr
Priority to FI0828/62A priority patent/FI43764B/fi
Priority to FR904689A priority patent/FR2140M/fr
Application granted granted Critical
Publication of DK98833C publication Critical patent/DK98833C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK169161AA 1961-04-25 1961-04-25 Fremgangsmåde til stabilisering af terapeutisk anvendelige plasminopløsninger. DK98833C (da)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DK169161AA DK98833C (da) 1961-04-25 1961-04-25 Fremgangsmåde til stabilisering af terapeutisk anvendelige plasminopløsninger.
NO144057A NO123024B (da) 1961-04-25 1962-04-16
SE04365/62A SE327779B (da) 1961-04-25 1962-04-18
GB15352/62A GB985498A (en) 1961-04-25 1962-04-19 Improvements in or relating to plasmin preparations
BE616779A BE616779A (fr) 1961-04-25 1962-04-24 Procédé de stabilisation de solutions de plasmine thérapeutiquement utiles
NL62277635A NL147634B (nl) 1961-04-25 1962-04-25 Werkwijze voor het bereiden van gestabiliseerde, therapeutisch bruikbare plasmine-oplossingen.
CH497562A CH456848A (fr) 1961-04-25 1962-04-25 Procédé de préparation d'un complexe de plasmine thérapeutiquement utile
FI0828/62A FI43764B (da) 1961-04-25 1962-04-25
FR904689A FR2140M (fr) 1961-04-25 1962-07-20 Solutions de plasmine stabilisées.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK169161AA DK98833C (da) 1961-04-25 1961-04-25 Fremgangsmåde til stabilisering af terapeutisk anvendelige plasminopløsninger.

Publications (1)

Publication Number Publication Date
DK98833C true DK98833C (da) 1964-05-25

Family

ID=8107240

Family Applications (1)

Application Number Title Priority Date Filing Date
DK169161AA DK98833C (da) 1961-04-25 1961-04-25 Fremgangsmåde til stabilisering af terapeutisk anvendelige plasminopløsninger.

Country Status (9)

Country Link
BE (1) BE616779A (da)
CH (1) CH456848A (da)
DK (1) DK98833C (da)
FI (1) FI43764B (da)
FR (1) FR2140M (da)
GB (1) GB985498A (da)
NL (1) NL147634B (da)
NO (1) NO123024B (da)
SE (1) SE327779B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2750159C3 (de) * 1977-11-09 1980-05-22 Lentia Gmbh, Chem. U. Pharm. Erzeugnisse - Industriebedarf, 8000 Muenchen Infusionslösung zur Behandlung von hepatischer Encephalopathie und ein Verfahren zu deren Herstellung
JPH0672105B2 (ja) * 1985-10-02 1994-09-14 持田製薬株式会社 血栓溶解剤及びその製法
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
US7544500B2 (en) 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6355243B1 (en) † 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
AU2003252039A1 (en) * 2002-07-23 2004-02-09 Vegenics Limited Methods and compositions for activating or inhibiting vegf-d and vegf-c
GB0228409D0 (en) 2002-12-06 2003-01-08 Thromb X Nv Pharmacological vitreolysis
US20060257391A1 (en) * 2005-05-11 2006-11-16 Bausch & Lomb Incorporated Non-surgical method for preventing or reducing the rate of the progression of non-proliferative diabetic retinopathy and the treatment of other ocular conditions
CA2726908C (en) 2008-06-04 2017-01-24 Talecris Biotherapeutics, Inc. Composition, method, and kit for preparing plasmin
JP5789521B2 (ja) 2009-03-03 2015-10-07 グリフオルス・セラピユーテイクス・インコーポレーテツドＧｒｉｆｏｌｓ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． プラスミノーゲンを製造するための組成物、方法およびキット；ならびにそれから製造されるプラスミン
CN106167797B (zh) * 2016-07-28 2019-04-09 国药集团武汉血液制品有限公司 人纤维蛋白溶解酶原的冻干制剂及其制备方法

Also Published As

Publication number Publication date
FR2140M (fr) 1963-11-12
GB985498A (en) 1965-03-10
SE327779B (da) 1970-08-31
NL147634B (nl) 1975-11-17
FI43764B (da) 1971-03-01
CH456848A (fr) 1968-05-31
BE616779A (fr) 1962-10-24
NO123024B (da) 1971-09-20

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