FR2140M - Solutions de plasmine stabilisées. - Google Patents

Solutions de plasmine stabilisées.

Info

Publication number
FR2140M
FR2140M FR904689A FR904689A FR2140M FR 2140 M FR2140 M FR 2140M FR 904689 A FR904689 A FR 904689A FR 904689 A FR904689 A FR 904689A FR 2140 M FR2140 M FR 2140M
Authority
FR
France
Prior art keywords
stabilized
solutions
plasmin solutions
stabilized plasmin
plasmin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR904689A
Other languages
English (en)
Inventor
Villy Johannes Jensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ILE D ETUDES ET DE BREVETS NOV
Original Assignee
ILE D ETUDES ET DE BREVETS NOV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR895444A external-priority patent/FR1334972A/fr
Application filed by ILE D ETUDES ET DE BREVETS NOV filed Critical ILE D ETUDES ET DE BREVETS NOV
Priority to FR904689A priority Critical patent/FR2140M/fr
Application granted granted Critical
Publication of FR2140M publication Critical patent/FR2140M/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
FR904689A 1961-04-25 1962-07-20 Solutions de plasmine stabilisées. Expired FR2140M (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR904689A FR2140M (fr) 1961-04-25 1962-07-20 Solutions de plasmine stabilisées.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK169161AA DK98833C (da) 1961-04-25 1961-04-25 Fremgangsmåde til stabilisering af terapeutisk anvendelige plasminopløsninger.
FR895444A FR1334972A (fr) 1962-04-24 1962-04-24 Procédé de stabilisation de solutions de plasmine
FR904689A FR2140M (fr) 1961-04-25 1962-07-20 Solutions de plasmine stabilisées.

Publications (1)

Publication Number Publication Date
FR2140M true FR2140M (fr) 1963-11-12

Family

ID=8107240

Family Applications (1)

Application Number Title Priority Date Filing Date
FR904689A Expired FR2140M (fr) 1961-04-25 1962-07-20 Solutions de plasmine stabilisées.

Country Status (9)

Country Link
BE (1) BE616779A (fr)
CH (1) CH456848A (fr)
DK (1) DK98833C (fr)
FI (1) FI43764B (fr)
FR (1) FR2140M (fr)
GB (1) GB985498A (fr)
NL (1) NL147634B (fr)
NO (1) NO123024B (fr)
SE (1) SE327779B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408347A1 (fr) * 1977-11-09 1979-06-08 Leopold Co Chem Pharm Fabrik G Solution pour infusion pour le traitement de l'encephalopathie hepatique et procede pour sa preparation

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0672105B2 (ja) * 1985-10-02 1994-09-14 持田製薬株式会社 血栓溶解剤及びその製法
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
US7544500B2 (en) 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6355243B1 (en) 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
CN1684706A (zh) 2002-07-23 2005-10-19 路德维格癌症研究所 活化或抑制vegf－d和vegf－c的方法和组合物
GB0228409D0 (en) 2002-12-06 2003-01-08 Thromb X Nv Pharmacological vitreolysis
US20060257391A1 (en) * 2005-05-11 2006-11-16 Bausch & Lomb Incorporated Non-surgical method for preventing or reducing the rate of the progression of non-proliferative diabetic retinopathy and the treatment of other ocular conditions
US8617863B2 (en) 2008-06-04 2013-12-31 Grifols Therapeutics Inc. Composition, method, and kit for preparing plasmin
US9206410B2 (en) 2009-03-03 2015-12-08 Grifols Therapeutics Inc. Compositions, methods and kits for preparing plasminogen and plasmin prepared therefrom
CN106167797B (zh) * 2016-07-28 2019-04-09 国药集团武汉血液制品有限公司 人纤维蛋白溶解酶原的冻干制剂及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408347A1 (fr) * 1977-11-09 1979-06-08 Leopold Co Chem Pharm Fabrik G Solution pour infusion pour le traitement de l'encephalopathie hepatique et procede pour sa preparation

Also Published As

Publication number Publication date
BE616779A (fr) 1962-10-24
CH456848A (fr) 1968-05-31
SE327779B (fr) 1970-08-31
FI43764B (fr) 1971-03-01
NO123024B (fr) 1971-09-20
GB985498A (en) 1965-03-10
NL147634B (nl) 1975-11-17
DK98833C (da) 1964-05-25

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