GB2090599B - Stabilized plasmin compositions and method for preparation thereof - Google Patents

Stabilized plasmin compositions and method for preparation thereof

Info

Publication number
GB2090599B
GB2090599B GB8200036A GB8200036A GB2090599B GB 2090599 B GB2090599 B GB 2090599B GB 8200036 A GB8200036 A GB 8200036A GB 8200036 A GB8200036 A GB 8200036A GB 2090599 B GB2090599 B GB 2090599B
Authority
GB
United Kingdom
Prior art keywords
preparation
plasmin compositions
stabilized
stabilized plasmin
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8200036A
Other versions
GB2090599A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Industri AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri AS filed Critical Novo Industri AS
Priority to GB8200036A priority Critical patent/GB2090599B/en
Publication of GB2090599A publication Critical patent/GB2090599A/en
Application granted granted Critical
Publication of GB2090599B publication Critical patent/GB2090599B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
GB8200036A 1981-01-05 1982-01-04 Stabilized plasmin compositions and method for preparation thereof Expired GB2090599B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB8200036A GB2090599B (en) 1981-01-05 1982-01-04 Stabilized plasmin compositions and method for preparation thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8100133 1981-01-05
GB8200036A GB2090599B (en) 1981-01-05 1982-01-04 Stabilized plasmin compositions and method for preparation thereof

Publications (2)

Publication Number Publication Date
GB2090599A GB2090599A (en) 1982-07-14
GB2090599B true GB2090599B (en) 1984-06-13

Family

ID=26278023

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8200036A Expired GB2090599B (en) 1981-01-05 1982-01-04 Stabilized plasmin compositions and method for preparation thereof

Country Status (1)

Country Link
GB (1) GB2090599B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI78117C (en) * 1984-06-25 1989-06-12 Suomen Sokeri Oy Process for preparing a stable glucose isomerase concentrate
DK8502857A (en) * 1984-06-25 1985-12-26
EP0170031A1 (en) * 1984-07-04 1986-02-05 Gesellschaft zur Förderung der industrieorientierten Forschung an den Schweizerischen Hochschulen und weiteren Institutionen Radioactive diagnostic agent for the detection of a venous thrombosis
GB8826429D0 (en) * 1988-11-11 1988-12-14 Univ Leeds Ind Service Ltd Enzyme stabilisation systems
GB9006642D0 (en) * 1990-03-24 1990-05-23 Gibson Timothy D Enzyme stabilisation
AU6138396A (en) * 1995-06-26 1997-01-30 Daiichi Pure Chemicals Co., Ltd. Stable plasmin solution
US6355243B1 (en) * 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US7544500B2 (en) 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
EP2297317A4 (en) 2008-06-04 2011-12-07 Talecris Biotherapeutics Inc Composition, method and kit for preparing plasmin
JP5789521B2 (en) 2009-03-03 2015-10-07 グリフオルス・セラピユーテイクス・インコーポレーテツドＧｒｉｆｏｌｓ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． Compositions, methods and kits for producing plasminogen; and plasmin produced therefrom

Also Published As

Publication number Publication date
GB2090599A (en) 1982-07-14

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee