BRPI0513897A - diferenciação de células-tronco - Google Patents
diferenciação de células-troncoInfo
- Publication number
- BRPI0513897A BRPI0513897A BRPI0513897-3A BRPI0513897A BRPI0513897A BR PI0513897 A BRPI0513897 A BR PI0513897A BR PI0513897 A BRPI0513897 A BR PI0513897A BR PI0513897 A BRPI0513897 A BR PI0513897A
- Authority
- BR
- Brazil
- Prior art keywords
- stem cell
- cell differentiation
- compositions
- disclosure
- methods
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0611—Primordial germ cells, e.g. embryonic germ cells [EG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/44—Thiols, e.g. mercaptoethanol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
Abstract
DIFERENCIAçãO DE CéLULAS-TRONCO. A presente invenção se refere à divulgação de composições e métodos para a identificação de tipos específicos de células.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59202704P | 2004-07-29 | 2004-07-29 | |
PCT/US2005/026976 WO2006015209A2 (en) | 2004-07-29 | 2005-07-29 | Differentiation of stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0513897A true BRPI0513897A (pt) | 2008-05-20 |
Family
ID=35058317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0513897-3A BRPI0513897A (pt) | 2004-07-29 | 2005-07-29 | diferenciação de células-tronco |
Country Status (9)
Country | Link |
---|---|
US (1) | US20060068496A1 (pt) |
EP (1) | EP1781776A2 (pt) |
JP (1) | JP2008507981A (pt) |
KR (1) | KR20070058453A (pt) |
CN (1) | CN101031640A (pt) |
AU (1) | AU2005267841A1 (pt) |
BR (1) | BRPI0513897A (pt) |
CA (1) | CA2575614A1 (pt) |
WO (1) | WO2006015209A2 (pt) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8053627B2 (en) * | 2005-06-14 | 2011-11-08 | University Of Chicago | Methods for treating demyelination disorders |
US7884260B2 (en) * | 2005-06-14 | 2011-02-08 | University Of Chicago | Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination |
US7423194B2 (en) * | 2005-06-14 | 2008-09-09 | University Of Chicago | Animal models for demyelination disorders |
WO2007146106A2 (en) * | 2006-06-05 | 2007-12-21 | Cryo- Cell International, Inc. | Procurement, isolation and cryopreservation of maternal placental cells |
US20080050814A1 (en) * | 2006-06-05 | 2008-02-28 | Cryo-Cell International, Inc. | Procurement, isolation and cryopreservation of fetal placental cells |
US20100173344A1 (en) * | 2006-08-24 | 2010-07-08 | Cedars-Sinai Medical Center | Methods for isolating and using pituitary adenoma stem cells and pituitary adenoma cells |
WO2008067408A2 (en) * | 2006-11-28 | 2008-06-05 | Cedars-Sinai Medical Center | Method of isolating and propagating stem cells from benign tumors |
WO2009075817A1 (en) * | 2007-12-06 | 2009-06-18 | Minerva Biotechnologies Corporation | Method for treating cancer using interference rna |
AU2009205886B2 (en) | 2008-01-18 | 2015-08-27 | Katholieke Universiteit Leuven | Stem cell aggregates and methods for making and using |
WO2010036923A1 (en) * | 2008-09-25 | 2010-04-01 | Salk Institute For Biological Studies | Induced pluripotent stem cells and methods of use |
SG176222A1 (en) * | 2009-05-27 | 2011-12-29 | Salk Inst For Biological Studi | Generation of genetically corrected disease-free induced pluripotent stem cells |
US9353164B2 (en) * | 2009-10-29 | 2016-05-31 | Vib Vzw | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
AU2011293440B2 (en) | 2010-08-24 | 2016-05-05 | Katholieke Universiteit Leuven | Non-static suspension culture of cell aggregates |
RS58526B1 (sr) * | 2011-12-06 | 2019-04-30 | Astellas Inst For Regenerative Medicine | Postupak usmerene diferencijacije koja proizvodi kornealne endotelijalne ćelije |
EP2900808B1 (en) * | 2012-09-28 | 2019-04-03 | Scripps Health | Methods of differentiating stem cells into chondrocytes |
WO2014070797A1 (en) | 2012-10-29 | 2014-05-08 | Scripps Health | Methods of producing pluripotent stem cells from chondrocytes |
JP6324395B2 (ja) | 2012-10-29 | 2018-05-16 | スクリップス ヘルス | 軟骨細胞を移植する方法 |
CN106795557A (zh) * | 2014-06-02 | 2017-05-31 | 瓦利保健系统公司 | 用于肺癌诊断的方法和系统 |
DK3347456T3 (da) * | 2015-09-08 | 2024-02-19 | Us Health | Fremgangsmåde til reproducerbar differentiering af retinale pigmentepitelceller af klinisk kvalitet |
SE540173C2 (en) * | 2016-04-20 | 2018-04-24 | Hiloprobe Ab | Marker genes for colorectal cancer classification, method for judging lymph node metastasis for prognosis of colorectal cancer and kit therefor |
WO2018053306A1 (en) * | 2016-09-15 | 2018-03-22 | University Of Miami | Double suicide gene vector systems for stem cells |
US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
US20200174021A1 (en) * | 2017-08-08 | 2020-06-04 | Queensland University Of Technology | Methods for diagnosis of early stage heart failure |
CN109022488A (zh) * | 2018-07-25 | 2018-12-18 | 佛山科学技术学院 | 一种条件性细胞永生化慢病毒载体及其构建方法和在猪卵巢颗粒细胞建系中的应用 |
CN109851677B (zh) * | 2019-02-26 | 2022-02-25 | 山东大学 | 一种特异性检测多硫化物的蛋白荧光探针及其制备方法与应用 |
AU2020263573A1 (en) * | 2019-04-24 | 2021-10-28 | Oregon Health & Science University | Promoter sequence and related products and uses thereof |
CN110643571B (zh) * | 2019-10-22 | 2021-07-27 | 康妍葆(北京)干细胞科技有限公司 | 人角蛋白6a在干细胞培养中的应用及产品 |
EP4129311A1 (en) * | 2020-03-31 | 2023-02-08 | Keio University | Therapeutic agent using genome-edited pluripotent stem cell |
CN111944033B (zh) * | 2020-08-06 | 2022-03-15 | 中国农业大学 | Rbp4蛋白或其编码基因在调控成肌细胞分化和融合中的应用 |
CN113801852B (zh) * | 2021-10-18 | 2023-08-18 | 齐齐哈尔医学院 | 一种gpd1l缺失人胚胎干细胞细胞株及其构建方法和应用 |
CN114752626A (zh) * | 2022-03-16 | 2022-07-15 | 重庆医科大学附属儿童医院 | 一种可逆性永生化ⅱ型肺泡上皮细胞及其构建与应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0532522B1 (en) * | 1990-05-16 | 1996-04-10 | Baylor College Of Medicine | A permanent human hepatocyte cell line and its use in a liver assist device (lad) |
US5928947A (en) * | 1992-07-27 | 1999-07-27 | California Institute Of Technology | Mammalian multipotent neural stem cells |
US5849553A (en) * | 1992-07-27 | 1998-12-15 | California Institute Of Technology | Mammalian multipotent neural stem cells |
US5453357A (en) * | 1992-10-08 | 1995-09-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
US5690926A (en) * | 1992-10-08 | 1997-11-25 | Vanderbilt University | Pluripotential embryonic cells and methods of making same |
US5368555A (en) * | 1992-12-29 | 1994-11-29 | Hepatix, Inc. | Organ support system |
GB9308271D0 (en) * | 1993-04-21 | 1993-06-02 | Univ Edinburgh | Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method |
US5811281A (en) * | 1993-07-12 | 1998-09-22 | Cornell Research Foundation, Inc. | Immortalized intestinal epithelial cell lines |
ES2217285T3 (es) * | 1994-11-08 | 2004-11-01 | Cellfactors Plc | Metodo para producir una linea celular neural humana. |
US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
US6534314B1 (en) * | 1996-06-14 | 2003-03-18 | Massachusetts Institute Of Technology | Methods and compositions for transforming cells |
US6090622A (en) * | 1997-03-31 | 2000-07-18 | The Johns Hopkins School Of Medicine | Human embryonic pluripotent germ cells |
GB0300208D0 (en) * | 2003-01-06 | 2003-02-05 | Oxford Biomedica Ltd | Insulin producing cells |
-
2005
- 2005-07-29 WO PCT/US2005/026976 patent/WO2006015209A2/en active Application Filing
- 2005-07-29 US US11/194,143 patent/US20060068496A1/en not_active Abandoned
- 2005-07-29 BR BRPI0513897-3A patent/BRPI0513897A/pt not_active IP Right Cessation
- 2005-07-29 KR KR1020077003713A patent/KR20070058453A/ko not_active Application Discontinuation
- 2005-07-29 CN CNA2005800330388A patent/CN101031640A/zh active Pending
- 2005-07-29 EP EP05776355A patent/EP1781776A2/en not_active Withdrawn
- 2005-07-29 JP JP2007523845A patent/JP2008507981A/ja active Pending
- 2005-07-29 AU AU2005267841A patent/AU2005267841A1/en not_active Abandoned
- 2005-07-29 CA CA002575614A patent/CA2575614A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN101031640A (zh) | 2007-09-05 |
JP2008507981A (ja) | 2008-03-21 |
AU2005267841A1 (en) | 2006-02-09 |
WO2006015209A3 (en) | 2006-06-08 |
EP1781776A2 (en) | 2007-05-09 |
KR20070058453A (ko) | 2007-06-08 |
CA2575614A1 (en) | 2006-02-09 |
US20060068496A1 (en) | 2006-03-30 |
WO2006015209A2 (en) | 2006-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |
|
B15K | Others concerning applications: alteration of classification |
Ipc: C12N 5/0735 (2010.01) |