BRPI0911759A2 - microorganismo para a produção de ácido metacrílico - Google Patents

microorganismo para a produção de ácido metacrílico

Info

Publication number
BRPI0911759A2
BRPI0911759A2 BRPI0911759A BRPI0911759A BRPI0911759A2 BR PI0911759 A2 BRPI0911759 A2 BR PI0911759A2 BR PI0911759 A BRPI0911759 A BR PI0911759A BR PI0911759 A BRPI0911759 A BR PI0911759A BR PI0911759 A2 BRPI0911759 A2 BR PI0911759A2
Authority
BR
Brazil
Prior art keywords
microorganism
production
methacrylic acid
methacrylic
acid
Prior art date
Application number
BRPI0911759A
Other languages
English (en)
Portuguese (pt)
Inventor
P Burgard Anthony
J Burk Mark
Pharkya Priti
E Osterhout Robin
Original Assignee
Genomatica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomatica Inc filed Critical Genomatica Inc
Publication of BRPI0911759A2 publication Critical patent/BRPI0911759A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01022—(S)-3-Amino-2-methylpropionate transaminase (2.6.1.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/01—Ammonia-lyases (4.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99002—Methylmalonyl-CoA mutase (5.4.99.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0911759A 2008-05-01 2009-04-30 microorganismo para a produção de ácido metacrílico BRPI0911759A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4973008P 2008-05-01 2008-05-01
PCT/US2009/042426 WO2009135074A2 (en) 2008-05-01 2009-04-30 Microorganisms for the production of methacrylic acid

Publications (1)

Publication Number Publication Date
BRPI0911759A2 true BRPI0911759A2 (pt) 2019-09-24

Family

ID=41255834

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911759A BRPI0911759A2 (pt) 2008-05-01 2009-04-30 microorganismo para a produção de ácido metacrílico

Country Status (7)

Country Link
US (6) US8241877B2 (enExample)
EP (1) EP2285973A4 (enExample)
JP (2) JP2011519561A (enExample)
AU (1) AU2009242615A1 (enExample)
BR (1) BRPI0911759A2 (enExample)
CA (1) CA2722680A1 (enExample)
WO (1) WO2009135074A2 (enExample)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006025821A1 (de) 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
JP2011519561A (ja) 2008-05-01 2011-07-14 ジェノマティカ， インコーポレイテッド メタクリル酸の産生のための微生物
US8129154B2 (en) 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
CA2735883C (en) 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
US20100184173A1 (en) * 2008-11-14 2010-07-22 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
US9637746B2 (en) 2008-12-15 2017-05-02 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
KR20110097951A (ko) 2008-12-16 2011-08-31 게노마티카 인코포레이티드 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법
EP2379728A4 (en) * 2008-12-22 2016-04-13 Greenlight Biosciences Inc COMPOSITIONS AND METHODS FOR THE PRODUCTION OF A COMPOUND
US9454640B2 (en) * 2009-02-26 2016-09-27 Intrexon Ceu, Inc. Mammalian cell line models and related methods
LT2438036T (lt) 2009-06-04 2017-06-26 Genomatica, Inc. Fermentacijos sultinio komponentų išskyrimo būdas
SI3392340T1 (sl) 2009-06-04 2022-05-31 Genomatica, Inc. Mikroorganizmi za proizvodnjo 1,4-BUTANDIOLA in pripadajoči postopki
JP2012529889A (ja) 2009-06-10 2012-11-29 ゲノマチカ， インク． Ｍｅｋ及び２−ブタノールの炭素効率のよい生合成のための微生物及び方法
AU2010306785B2 (en) 2009-10-13 2016-01-14 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA, putrescine and related compounds, and methods related thereto
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
CN109136161A (zh) 2009-12-10 2019-01-04 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
MX336229B (es) 2010-05-05 2016-01-08 Genomatica Inc Microorganismos y metodos para la biosintesis de butadieno.
WO2011140516A2 (en) 2010-05-07 2011-11-10 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
WO2012030980A1 (en) 2010-08-31 2012-03-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
RU2013148813A (ru) * 2011-04-01 2015-06-10 Дженоматика, Инк. Микроорганизмы для получения метакриловой кислоты и сложные эфиры метакриловой кислоты и относящиеся к ним способы
US20120330560A1 (en) * 2011-06-23 2012-12-27 Ramot At Tel-Aviv University Ltd. Method and system for predicting pertubations altering metabolic states
SG2014012520A (en) 2011-07-12 2014-06-27 Scientist Of Fortune Sa Recombinant microorganism for the production of useful metabolites
MY165731A (en) 2011-07-29 2018-04-20 Mitsui Chemicals Inc Microorganism having carbon dioxide fixation cycle introduced thereinto
SG2014014377A (en) 2011-09-09 2014-05-29 Greenlight Biosciences Inc Cell-free preparation of carbapenems
US8940509B2 (en) 2011-11-02 2015-01-27 Genomatica, Inc. Microorganisms and methods for the production of caprolactone
DE102012207921A1 (de) 2012-05-11 2013-11-14 Evonik Industries Ag Mehrstufiges Syntheseverfahren mit Synthesegas
US9803209B2 (en) 2012-05-18 2017-10-31 Novozymes A/S Bacterial mutants with improved transformation efficiency
EP3831951A3 (en) 2012-06-04 2021-09-15 Genomatica, Inc. Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds
EP2674489A1 (en) * 2012-06-15 2013-12-18 Evonik Industries AG Biotechnological 2-hydroxyisobutyric acid production
AU2013314153B2 (en) * 2012-09-10 2016-05-12 Mitsubishi Chemical Corporation Method for producing methacrylic acid and/or ester thereof
ES2689477T3 (es) 2012-09-10 2018-11-14 Mitsubishi Chemical Corporation Método para producir éster del ácido metacrílico
WO2014052630A1 (en) 2012-09-27 2014-04-03 Novozymes, Inc. Bacterial mutants with improved transformation efficiency
EP2935598A1 (en) 2012-12-21 2015-10-28 Greenlight Biosciences Inc. Cell-free system for converting methane into fuel, pyruvate or isobutanol
BE1021047B1 (fr) * 2013-01-18 2015-02-25 Man To Tree S.A. Actinobacillus succinogenes genetiquement modifiee et son utilisation pour la production d'acide succinique
MY172023A (en) 2013-01-24 2019-11-12 Mitsui Chemicals Inc Microorganism having carbon dioxide fixation cycle introduced thereinto
CA2900536A1 (en) 2013-03-15 2014-09-25 Genomatica, Inc. Process and systems for obtaining 1,4-butanediol from fermentation broths
EP2971021A4 (en) 2013-03-15 2016-12-21 Genomatica Inc MICROORGANISMS AND METHOD FOR THE PRODUCTION OF BUTADIENE AND RELATED COMPOUNDS BY FORMATASSIMILATION
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
JP6202001B2 (ja) * 2013-08-01 2017-09-27 三菱ケミカル株式会社 メタクリリル−ＣｏＡの製造法
AU2014306074B2 (en) 2013-08-05 2018-08-30 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
AU2014311940B2 (en) 2013-08-26 2018-01-04 Stichting Wageningen Research Process for the production of methacrylic acid
PL3077501T3 (pl) 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
WO2015100338A2 (en) 2013-12-27 2015-07-02 Genomatica, Inc. Methods and organisms with increased carbon flux efficiencies
CN105940100A (zh) * 2014-01-28 2016-09-14 朗泽科技新西兰有限公司 对丁酸具有增加的耐受性的细菌
CN106062204A (zh) 2014-03-07 2016-10-26 三菱丽阳株式会社 甲基丙烯酸酯的制造方法及新的甲基丙烯酸酯合成酶
EP3741865B1 (en) 2014-09-18 2024-03-13 Genomatica, Inc. Non-natural microbial organisms with improved energetic efficiency
WO2016130597A1 (en) * 2015-02-10 2016-08-18 GeneSys Consulting, LLC Methylmalonic acid compositions, biological methods for making same, and microorganisms for making same
CA2980172A1 (en) 2015-03-30 2016-10-06 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
DE102016212497B4 (de) 2015-07-13 2024-04-25 Sk Innovation Co., Ltd. Mutanter Mikroorganismus, der ein Gen umfasst, das Methylmalonyl-CoA-Reductase codiert, und seine Verwendung
AU2016340470B2 (en) 2015-10-23 2019-10-03 Mitsubishi Chemical Corporation Biological production of methyl methacrylate
SG11201803164SA (en) 2015-10-30 2018-05-30 Genomatica Inc Methanol dehydrogenase fusion proteins
RU2018138975A (ru) 2016-04-06 2020-05-12 Гринлайт Байосайенсис, Инк. Бесклеточная продукция рибонуклеиновой кислоты
KR20190100386A (ko) 2017-01-06 2019-08-28 그린라이트 바이오사이언시스, 아이엔씨. 당의 무세포 생산
SG11202003192UA (en) 2017-10-11 2020-05-28 Greenlight Biosciences Inc Methods and compositions for nucleoside triphosphate and ribonucleic acid production
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
EP3746559A4 (en) 2018-02-01 2021-12-22 INVISTA Textiles (U.K.) Limited METHODS AND MATERIALS FOR THE BIOSYNTHESIS OF BETA HYDROXY FATTY ACID ANIONS AND / OR DERIVATIVES THEREOF AND / OR COMPOUNDS ASSOCIATED WITH THEM
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
EP3814515A2 (en) 2018-06-26 2021-05-05 Genomatica, Inc. Engineered microorganisms with g3p---> 3pg enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy
WO2022103799A1 (en) * 2020-11-10 2022-05-19 Industrial Microbes, Inc. Microorganisms capable of producing poly(hiba) from feedstock
WO2023190564A1 (ja) * 2022-03-29 2023-10-05 国立研究開発法人理化学研究所 メタクリル酸の製造方法
CN115851799B (zh) * 2022-12-15 2025-01-28 南京纽邦生物科技有限公司 L-3-氨基异丁酸生产菌株、其构建方法及其用途

Family Cites Families (162)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3513209A (en) 1968-08-19 1970-05-19 Du Pont Method of making 1,4-cyclohexadiene
US4076948A (en) 1968-10-10 1978-02-28 El Paso Products Company Process for treatment of adipic acid mother liquor
GB1230276A (enExample) 1968-12-09 1971-04-28
US3965182A (en) 1969-10-02 1976-06-22 Ethyl Corporation Preparation of aniline from phenol and ammonia
JPS4831084B1 (enExample) 1970-09-04 1973-09-26
GB1344557A (en) 1972-06-23 1974-01-23 Mitsubishi Petrochemical Co Process for preparing 1,4-butanediol
JPS5543759B2 (enExample) 1972-06-28 1980-11-07
DE2455617C3 (de) 1974-11-23 1982-03-18 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Butandiol und/oder Tetrahydrofuran über die Zwischenstufe des γ-Butyrolactons
DE2501499A1 (de) 1975-01-16 1976-07-22 Hoechst Ag Verfahren zur herstellung von butandiol-(1.4)
US4190495A (en) 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
US4301077A (en) 1980-12-22 1981-11-17 Standard Oil Company Process for the manufacture of 1-4-butanediol and tetrahydrofuran
IT1190783B (it) 1981-04-29 1988-02-24 Davy Mckee Oil & Chem Processo per l'idrogenolisi di esteri di acidi carbossilici
JPS60114197A (ja) 1983-11-25 1985-06-20 Agency Of Ind Science & Technol 微生物によるジカルボン酸の製造法
US4871667A (en) 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
US4652685A (en) 1985-11-15 1987-03-24 General Electric Company Hydrogenation of lactones to glycols
US5143834A (en) 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5168055A (en) 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
ES2036188T3 (es) 1986-06-11 1993-05-16 Michigan Biotechnology Institute Un procedimiento para la produccion de acido succinico por fermentacion anaerobia.
US5182199A (en) 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
US5219757A (en) 1988-04-27 1993-06-15 Daicel Chemical Industries, Ltd. Production of optically active 1,3-butanediol by asymmetric assimilation or reduction of 4-hydroxy-2-butanone
CA2062753C (en) 1989-04-27 2005-04-26 N. Robert Ward, Jr. Precipitate test for microorganisms
US5192673A (en) 1990-04-30 1993-03-09 Michigan Biotechnology Institute Mutant strain of C. acetobutylicum and process for making butanol
US5079143A (en) 1990-05-02 1992-01-07 The Upjohn Company Method of indentifying compounds useful as antiparasitic drugs
EP0769557B1 (en) 1990-10-15 2000-11-15 Daicel Chemical Industries, Ltd. Process for producing optically active 1,3-butanediol
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
IL100572A (en) 1991-01-03 1997-01-10 Lepetit Spa Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them
US5416020A (en) 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
US6136577A (en) 1992-10-30 2000-10-24 Bioengineering Resources, Inc. Biological production of ethanol from waste gases with Clostridium ljungdahlii
FR2702492B1 (fr) 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
US5487987A (en) 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
US5521075A (en) 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
US5700934A (en) 1995-03-01 1997-12-23 Dsm N.V. Process for the preparation of epsilon-caprolactam and epsilon-caprolactam precursors
US5478952A (en) 1995-03-03 1995-12-26 E. I. Du Pont De Nemours And Company Ru,Re/carbon catalyst for hydrogenation in aqueous solution
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
US5686276A (en) 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
FR2736927B1 (fr) 1995-07-18 1997-10-17 Rhone Poulenc Fibres & Polymer Enzymes a activite amidase, outils genetiques et microorganismes hotes permettant leur obtention et procede d'hydrolyse mettant en oeuvre lesdites enzymes
US5573931A (en) 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
US5770435A (en) 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
US5869301A (en) 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
JP2000506012A (ja) 1996-02-27 2000-05-23 ミシガン ステイト ユニヴァーシティー サーモアンエアロバクター・エタノリカス３９ｅの第二級アルコールデヒドロゲナーゼをコードする遺伝子のクローニング及び発現並びに酵素の生化学的特徴付け
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
JP4101295B2 (ja) 1996-07-01 2008-06-18 バイオエンジニアリング・リソーシズ・インコーポレーテツド 廃ガスからの酢酸の生物学的生産
KR100459818B1 (ko) 1996-09-02 2004-12-03 이. 아이. 두퐁 드 느무르 앤드 컴퍼니 ε-카프로락탐의 제조방법
US6117658A (en) 1997-02-13 2000-09-12 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units
KR100516986B1 (ko) 1997-02-19 2005-09-26 코닌클리즈케 디에스엠 엔.브이. 6-아미노카프론산 유도체를 과열 수증기와 접촉시킴으로써 촉매 없이 카프로락탐을 제조하는 방법
US6274790B1 (en) 1997-04-14 2001-08-14 The University Of British Columbia Nucleic acids encoding a plant enzyme involved in very long chain fatty acid synthesis
KR19990013007A (ko) 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ｓｓ373(ｋｃｔｃ 8818ｐ)과 이를 이용한숙신산의 생산방법
JPH11103863A (ja) 1997-10-08 1999-04-20 Nippon Shokubai Co Ltd マレイン酸異性化酵素遺伝子
US6280986B1 (en) 1997-12-01 2001-08-28 The United States Of America As Represented By The Secretary Of Agriculture Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities
US20030087381A1 (en) 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
WO1999053035A1 (en) 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
US6159738A (en) 1998-04-28 2000-12-12 University Of Chicago Method for construction of bacterial strains with increased succinic acid production
US20010045575A1 (en) * 1998-05-01 2001-11-29 Mark Ashby Device and method for facilitating hemostasis of a biopsy tract
DE19820652A1 (de) 1998-05-08 1999-11-11 Basf Ag Kationische Rutheniumkomplexe, Verfahren zu ihrer Herstellung und ihre Verwendung
US6432686B1 (en) 1998-05-12 2002-08-13 E. I. Du Pont De Nemours And Company Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport
US6444784B1 (en) 1998-05-29 2002-09-03 Exxonmobil Research & Engineering Company Wax crystal modifiers (LAW657)
US6187569B1 (en) 1998-07-02 2001-02-13 E. I. Du Pont De Nemours And Company Microbial production of terephthalic acid and isophthalic acid
WO2000004163A1 (en) 1998-07-15 2000-01-27 E.I. Du Pont De Nemours And Company Tetrahydrofolate metabolism enzymes
DE19856136C2 (de) 1998-12-04 2002-10-24 Pasteur Institut Verfahren und Vorrichtung zur Selektion beschleunigter Proliferation lebender Zellen in Suspension
WO2000046405A2 (en) 1999-02-02 2000-08-10 Bernhard Palsson Methods for identifying drug targets based on genomic sequence data
US6686310B1 (en) 1999-02-09 2004-02-03 E. I. Du Pont De Nemours And Company High surface area sol-gel route prepared hydrogenation catalysts
US6365376B1 (en) 1999-02-19 2002-04-02 E. I. Du Pont De Nemours And Company Genes and enzymes for the production of adipic acid intermediates
US6448473B1 (en) 1999-03-05 2002-09-10 Monsanto Technology Llc Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
CA2374482C (en) 1999-05-21 2012-09-18 Cargill Dow Llc Methods and materials for the synthesis of organic products
WO2001016346A1 (en) 1999-08-30 2001-03-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
US6660857B2 (en) 2000-02-03 2003-12-09 Dsm N.V. Process for the preparation of ε-caprolactam
US6878861B2 (en) 2000-07-21 2005-04-12 Washington State University Research Foundation Acyl coenzyme A thioesterases
NZ523484A (en) 2000-07-25 2005-01-28 Emmaus Foundation Inc Methods for increasing the production of ethanol from microbial fermentation
JP4490628B2 (ja) 2000-11-20 2010-06-30 カーギル インコーポレイテッド ３−ヒドロキシプロピオン酸および他の有機化合物
US7109010B2 (en) 2000-11-22 2006-09-19 Nature Works Llc Methods and materials for the synthesis of organic products
CN1358841A (zh) 2000-12-11 2002-07-17 云南省微生物研究所 云南链霉菌
US7501268B2 (en) 2000-12-28 2009-03-10 Toyota Jidosha Kabushiki Kaisha Methods of producing prenyl alcohols
CA2434224C (en) 2001-01-10 2013-04-02 The Penn State Research Foundation Method and system for modeling cellular metabolism
US7127379B2 (en) 2001-01-31 2006-10-24 The Regents Of The University Of California Method for the evolutionary design of biochemical reaction networks
US20030059792A1 (en) 2001-03-01 2003-03-27 Palsson Bernhard O. Models and methods for determining systemic properties of regulated reaction networks
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
CN1279013C (zh) 2001-05-07 2006-10-11 嘉吉有限公司 羧酸及其衍生物的制备方法
JP4630486B2 (ja) 2001-05-28 2011-02-09 ダイセル化学工業株式会社 新規な（ｒ）−２，３−ブタンジオール脱水素酵素、その製造方法、及びこれを利用した光学活性アルコールの製造方法
CA2356540A1 (en) 2001-08-30 2003-02-28 Emory University Expressed dna sequences involved in mitochondrial functions
CA2466133A1 (en) 2001-11-02 2003-05-15 Rice University Recycling system for manipulation of intracellular nadh availability
DE60327804D1 (de) 2002-01-18 2009-07-09 Novozymes As Alanin-2,3-aminomutase
US6582943B1 (en) * 2002-02-05 2003-06-24 E. I. Du Pont De Nemours And Company Method for producing 2-hydroxyisobutyric acid and methacrylic acid from acetone cyanohydrin
WO2003066863A1 (fr) 2002-02-06 2003-08-14 Showa Denko K.K. Gene reductase d'un compose carbonyle alpha-substitue-alpha, beta-insature
US20030224363A1 (en) 2002-03-19 2003-12-04 Park Sung M. Compositions and methods for modeling bacillus subtilis metabolism
CA2480216A1 (en) 2002-03-29 2003-10-09 Genomatica, Inc. Human metabolic models and methods
US20050287655A1 (en) 2002-05-10 2005-12-29 Kyowa Hakko Kogyo Co., Ltd. Process for producing mevalonic acid
US7856317B2 (en) 2002-06-14 2010-12-21 Genomatica, Inc. Systems and methods for constructing genomic-based phenotypic models
US7826975B2 (en) 2002-07-10 2010-11-02 The Penn State Research Foundation Method for redesign of microbial production systems
EP1532516A4 (en) 2002-07-10 2007-05-23 Penn State Res Found Method for determining gene knockout strategies
WO2004007688A2 (en) * 2002-07-15 2004-01-22 Kosan Biosciences, Inc. Metabolic pathways for starter units in polyketide biosynthesis
AU2003287028B2 (en) 2002-10-04 2008-09-04 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
AU2003222214B2 (en) 2002-10-15 2010-08-12 The Regents Of The University Of California Methods and systems to identify operational reaction pathways
AU2003287625A1 (en) 2002-11-06 2004-06-03 University Of Florida Materials and methods for the efficient production of acetate and other products
CN1802341A (zh) 2003-01-13 2006-07-12 卡吉尔公司 制备工业化学品的方法
US7432091B2 (en) 2003-02-24 2008-10-07 Research Institute Of Innovative Technology For The Earth Highly efficient hydrogen production method using microorganism
RU2268300C2 (ru) 2003-04-07 2006-01-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ОБЛАДАЮЩИХ ПОВЫШЕННОЙ ЭКСПРЕССИЕЙ ГЕНА pckA
WO2005010182A1 (ja) 2003-07-29 2005-02-03 Research Institute Of Innovative Technology For The Earth コリネ型細菌形質転換体及びそれを用いるジカルボン酸の製造方法
US7927859B2 (en) 2003-08-22 2011-04-19 Rice University High molar succinate yield bacteria by increasing the intracellular NADH availability
WO2005026349A1 (ja) 2003-09-17 2005-03-24 Mitsubishi Chemical Corporation 非アミノ有機酸の製造方法
WO2005026338A1 (en) 2003-09-18 2005-03-24 Ciba Specialty Chemicals Holding Inc. Alcohol dehydrogenases with increased solvent and temperature stability
FR2862068B1 (fr) 2003-11-06 2007-10-12 Metabolic Explorer Sa Souches de microorganismes optimisees pour des voies de biosyntheses consommatrices de nadph
US7244610B2 (en) 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
FR2864967B1 (fr) 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
CN1926240B (zh) 2004-01-19 2010-06-02 帝斯曼知识产权资产管理有限公司 6-氨基己酸的生物化学合成
US7608700B2 (en) 2004-03-08 2009-10-27 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
DE102004031177A1 (de) 2004-06-29 2006-01-19 Henkel Kgaa Neue Geruchsstoffe bildende Genprodukte von Bacillus licheniformis und darauf aufbauende verbesserte biotechnologische Produktionsverfahren
US7262046B2 (en) 2004-08-09 2007-08-28 Rice University Aerobic succinate production in bacteria
CN101044245B (zh) 2004-08-27 2012-05-02 莱斯大学 具有增加的琥珀酸产量的突变大肠杆菌菌株
EP2434015B1 (en) 2004-09-09 2013-11-20 Research Institute Of Innovative Technology For The Earth DNA fragment having promoter function
EP1789569A2 (en) 2004-09-17 2007-05-30 Rice University High succinate producing bacteria
US7569380B2 (en) 2004-12-22 2009-08-04 Rice University Simultaneous anaerobic production of isoamyl acetate and succinic acid
JP2006204255A (ja) 2005-01-31 2006-08-10 Canon Inc アセチル−ＣｏＡアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法
EP1874334A4 (en) 2005-04-15 2011-03-30 Vascular Biogenics Ltd COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES
EP1899472B1 (en) 2005-06-20 2017-09-27 Archer-Daniels-Midland Company Altered glyoxylate shunt for improved production of aspartate-derived amino acids and chemicals
KR100676160B1 (ko) 2005-08-19 2007-02-01 한국과학기술원 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
KR100679638B1 (ko) 2005-08-19 2007-02-06 한국과학기술원 포메이트 디하이드로게나제 ｄ 또는 ｅ를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법
AU2006287257A1 (en) 2005-09-09 2007-03-15 Genomatica, Inc. Methods and organisms for the growth-coupled production of succinate
WO2007039415A1 (en) 2005-09-19 2007-04-12 Ciba Specialty Chemicals Holding Inc. Biocatalytic manufacturing of (meth)acrylic esters
US9297028B2 (en) 2005-09-29 2016-03-29 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US20080274526A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of isobutanol
NZ566406A (en) 2005-10-26 2012-04-27 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
DE102006017760A1 (de) 2006-03-24 2007-09-27 Ufz-Umweltforschungszentrum Leipzig-Halle Gmbh Verfahren zur enzymatischen Herstellung von 2-Hydroxy-2-methylcarbonsäuren
MY157798A (en) 2006-05-01 2016-07-29 Univ Florida Ethanol production in non-recombination hosts
US8206970B2 (en) 2006-05-02 2012-06-26 Butamax(Tm) Advanced Biofuels Llc Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase
DE102006025821A1 (de) 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
RU2311231C1 (ru) 2006-08-15 2007-11-27 ООО "Объединенный центр исследований и разработок" Катализатор для получения эфиров акриловой кислоты по реакции метатезиса диалкилмалеатов (варианты) и каталитическая композиция на его основе
BRPI0716212A2 (pt) 2006-08-30 2013-10-15 Cargill Inc Beta-alanina/alfa-cetoglutarato aminotransferase para produção de ácido 3-hidroxipropiônico
US8017364B2 (en) 2006-12-12 2011-09-13 Butamax(Tm) Advanced Biofuels Llc Solvent tolerant microorganisms
WO2008080124A2 (en) 2006-12-21 2008-07-03 Gevo, Inc. Butanol production by metabolically engineered yeast
AU2008206403A1 (en) 2007-01-12 2008-07-24 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms
CA2678946C (en) 2007-03-16 2019-02-12 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
DE102007015583A1 (de) 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg Ein Enzym zur Herstellung von Methylmalonyl-Coenzym A oder Ethylmalonyl-Coenzym A sowie dessen Verwendung
EP2147111A4 (en) 2007-04-18 2010-06-23 Gevo Inc MANIPULATED MICROORGANISMS FOR THE MANUFACTURE OF ISOPROPANOL
KR101573775B1 (ko) 2007-04-18 2015-12-04 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 고도 활성 케톨-산 리덕토아이소머라아제 효소를 이용한 아이소부탄올의 발효 생산
US20080274522A1 (en) 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of 2-butanone
US8426174B2 (en) 2007-05-02 2013-04-23 Butamax(Tm) Advanced Biofuels Llc Method for the production of 2-butanol
WO2008144060A2 (en) 2007-05-17 2008-11-27 Tetravitae Bioscience, Inc. Methods and compositions for producing solvents
JP5449142B2 (ja) * 2007-06-01 2014-03-19 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング メタクリル酸又はメタクリルエステルの製造方法
EP2158324A1 (en) 2007-06-15 2010-03-03 Evonik Degussa GmbH Microorganisms with deregulated vitamin b12 system
EP2017344A1 (en) 2007-07-20 2009-01-21 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Production of itaconic acid
CN101970673A (zh) 2007-07-23 2011-02-09 帝斯曼知识产权资产管理有限公司 真核细胞中的丁醇生产
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
AU2008310573A1 (en) 2007-10-12 2009-04-16 The Regents Of The University Of California Microorganism engineered to produce isopropanol
US8183028B2 (en) 2007-12-21 2012-05-22 Ls9, Inc. Methods and compositions for producing olefins
CA2712779C (en) 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
WO2009103026A1 (en) 2008-02-15 2009-08-20 Gevo, Inc. Engineered microorganisms for producing isopropanol
US20090246842A1 (en) 2008-02-15 2009-10-01 Gevo, Inc. Engineered microorganisms for producing propanol
CN102015995B (zh) 2008-03-03 2014-10-22 焦耳无限科技公司 产生碳基目的产物的二氧化碳固定工程微生物
SI2265709T1 (en) 2008-03-27 2018-03-30 Genomatica, Inc. MICROORGANISMS FOR PREPARATION OF ADYPIC ACID AND OTHER COMPOUNDS
CN102016006B (zh) 2008-04-25 2013-04-10 财团法人地球环境产业技术研究机构 具有异丙醇生产能力的棒状细菌转化体
JP2011519561A (ja) 2008-05-01 2011-07-14 ジェノマティカ， インコーポレイテッド メタクリル酸の産生のための微生物
US8129154B2 (en) 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
WO2010022763A1 (en) 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
US8357826B2 (en) 2008-10-16 2013-01-22 Karl Kharas Methods and apparatus for synthesis of alcohols from syngas
EP3260532A1 (en) 2008-12-12 2017-12-27 CJ Research Center LLC Green process and compositions for producing poly(5hv) and 5 carbon chemicals
US20100191224A1 (en) 2008-12-15 2010-07-29 C.R. Bard, Inc. Magnetic detent mechanism for medical instruments
KR20110097951A (ko) 2008-12-16 2011-08-31 게노마티카 인코포레이티드 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법
SI3392340T1 (sl) 2009-06-04 2022-05-31 Genomatica, Inc. Mikroorganizmi za proizvodnjo 1,4-BUTANDIOLA in pripadajoči postopki
CN109136161A (zh) 2009-12-10 2019-01-04 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体

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