BRPI0718183B8 - proteína hemaglutinina h5 de vírus influenza e seus usos, vacina, seu processo de produção e seus usos, bem como kit de partes - Google Patents
proteína hemaglutinina h5 de vírus influenza e seus usos, vacina, seu processo de produção e seus usos, bem como kit de partesInfo
- Publication number
- BRPI0718183B8 BRPI0718183B8 BRPI0718183A BRPI0718183A BRPI0718183B8 BR PI0718183 B8 BRPI0718183 B8 BR PI0718183B8 BR PI0718183 A BRPI0718183 A BR PI0718183A BR PI0718183 A BRPI0718183 A BR PI0718183A BR PI0718183 B8 BRPI0718183 B8 BR PI0718183B8
- Authority
- BR
- Brazil
- Prior art keywords
- well
- vaccine
- kit
- protein
- parts
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 101710154606 Hemagglutinin Proteins 0.000 title 1
- 101710093908 Outer capsid protein VP4 Proteins 0.000 title 1
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 title 1
- 101710176177 Protein A56 Proteins 0.000 title 1
- 239000000185 hemagglutinin Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 241000712461 unidentified influenza virus Species 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 239000013598 vector Substances 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 1
- 108010029566 avian influenza A virus hemagglutinin Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86314206P | 2006-10-27 | 2006-10-27 | |
| US60/863,142 | 2006-10-27 | ||
| US11/923,326 | 2007-10-24 | ||
| US11/923,326 US8202967B2 (en) | 2006-10-27 | 2007-10-24 | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
| PCT/US2007/082699 WO2008052173A2 (en) | 2006-10-27 | 2007-10-26 | Novel h5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0718183A2 BRPI0718183A2 (pt) | 2013-11-05 |
| BRPI0718183B1 BRPI0718183B1 (pt) | 2020-03-17 |
| BRPI0718183B8 true BRPI0718183B8 (pt) | 2022-05-24 |
Family
ID=39325469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0718183A BRPI0718183B8 (pt) | 2006-10-27 | 2007-10-26 | proteína hemaglutinina h5 de vírus influenza e seus usos, vacina, seu processo de produção e seus usos, bem como kit de partes |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US8202967B2 (enExample) |
| EP (1) | EP2086576B8 (enExample) |
| JP (2) | JP5442442B2 (enExample) |
| KR (2) | KR20150041200A (enExample) |
| AU (1) | AU2007308869B2 (enExample) |
| BR (1) | BRPI0718183B8 (enExample) |
| CA (1) | CA2664914C (enExample) |
| CO (1) | CO6210831A2 (enExample) |
| DK (1) | DK2086576T3 (enExample) |
| ES (1) | ES2391123T3 (enExample) |
| MX (1) | MX2009004243A (enExample) |
| MY (1) | MY150226A (enExample) |
| PL (1) | PL2086576T3 (enExample) |
| PT (1) | PT2086576E (enExample) |
| RU (1) | RU2479589C2 (enExample) |
| SG (1) | SG176419A1 (enExample) |
| SI (1) | SI2086576T1 (enExample) |
| WO (1) | WO2008052173A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200731986A (en) * | 2005-10-28 | 2007-09-01 | Boehringer Ingelheim Vetmed | Use of vaccines for the treatment/prevention of the transmission of pathogens |
| US8202967B2 (en) * | 2006-10-27 | 2012-06-19 | Boehringer Ingelheim Vetmedica, Inc. | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
| KR20170001720A (ko) | 2007-03-14 | 2017-01-04 | 다케다 백신즈 인코포레이티드 | 바이러스 유사 입자 정제 |
| EP2367566B2 (en) | 2008-11-28 | 2019-11-27 | Boehringer Ingelheim Animal Health USA Inc. | Recombinant avian influenza vaccine and uses thereof |
| US20110305748A1 (en) * | 2010-03-11 | 2011-12-15 | Immune Design, Corp. | Vaccines for Pandemic Influenza |
| CA2813078A1 (en) | 2010-10-04 | 2012-04-12 | Massachusetts Institute Of Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
| AR088028A1 (es) * | 2011-08-15 | 2014-05-07 | Boehringer Ingelheim Vetmed | Proteinas h5, de h5n1 para un uso medicinal |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| EP2958586B1 (en) * | 2013-02-21 | 2018-09-05 | Boehringer Ingelheim Vetmedica GmbH | H5 proteins of h5n1 influenza virus for use as a medicament |
| JP2015015931A (ja) * | 2013-07-12 | 2015-01-29 | 株式会社Umnファーマ | ウイルス様粒子を含む培養物の製造方法 |
| JOP20190088A1 (ar) | 2016-10-21 | 2019-04-21 | Us Agriculture | نواقل مؤتلفة للتعبير عن مولدات مضاد فيروس انفلونزا الطيور و استخداماتها |
| JP7337921B2 (ja) * | 2018-11-06 | 2023-09-04 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 鳥インフルエンザウイルスh5亜型に対する免疫原性組成物 |
| CN117229370B (zh) * | 2022-06-08 | 2024-11-01 | 中科南京生命健康高等研究院 | H5n6禽流感广谱性疫苗的开发及其应用 |
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| US382425A (en) | 1888-05-08 | Brandt | ||
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| US4769331A (en) | 1981-09-16 | 1988-09-06 | University Patents, Inc. | Recombinant methods and materials |
| US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| US5833975A (en) | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
| US5174993A (en) | 1981-12-24 | 1992-12-29 | Health Research Inc. | Recombinant avipox virus and immunological use thereof |
| US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
| US5364773A (en) | 1991-03-07 | 1994-11-15 | Virogenetics Corporation | Genetically engineered vaccine strain |
| US5505941A (en) | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| US5338683A (en) | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
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| WO1990001543A1 (fr) | 1988-07-29 | 1990-02-22 | Intracel Corporation | Procede d'expression genetique de proteines heterologues par des cellules transfectees in vivo |
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| JP3250802B2 (ja) | 1989-03-21 | 2002-01-28 | バイカル・インコーポレイテッド | 脊椎動物における外因性ポリヌクレオチド配列の発現 |
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| ATE181108T1 (de) | 1991-08-26 | 1999-06-15 | Immuno Ag | Direkt molekuläre klonierung eines modifizierten genoms eines chordopocken-virus |
| US5643578A (en) | 1992-03-23 | 1997-07-01 | University Of Massachusetts Medical Center | Immunization by inoculation of DNA transcription unit |
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| RU2283139C1 (ru) * | 2005-03-21 | 2006-09-10 | Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации | Способ получения антигенов для вакцины против вирусов гриппа |
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| TWI488968B (zh) | 2005-10-18 | 2015-06-21 | Novavax Inc | 功能性流行性感冒類病毒顆粒(VLPs) |
| TW200731986A (en) * | 2005-10-28 | 2007-09-01 | Boehringer Ingelheim Vetmed | Use of vaccines for the treatment/prevention of the transmission of pathogens |
| US20100150941A1 (en) | 2006-09-13 | 2010-06-17 | Dso National Laboratories | Hemagglutinin antibody and uses thereof |
| US8202967B2 (en) * | 2006-10-27 | 2012-06-19 | Boehringer Ingelheim Vetmedica, Inc. | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
| WO2011136738A1 (en) | 2010-04-30 | 2011-11-03 | Temasek Life Sciences Laboratory Limited | Universal vaccine against h5n1 lineages |
| AR088028A1 (es) | 2011-08-15 | 2014-05-07 | Boehringer Ingelheim Vetmed | Proteinas h5, de h5n1 para un uso medicinal |
| EP2958586B1 (en) | 2013-02-21 | 2018-09-05 | Boehringer Ingelheim Vetmedica GmbH | H5 proteins of h5n1 influenza virus for use as a medicament |
-
2007
- 2007-10-24 US US11/923,326 patent/US8202967B2/en active Active
- 2007-10-26 MX MX2009004243A patent/MX2009004243A/es active IP Right Grant
- 2007-10-26 RU RU2009119597/10A patent/RU2479589C2/ru active
- 2007-10-26 DK DK07863555.4T patent/DK2086576T3/da active
- 2007-10-26 KR KR20157008683A patent/KR20150041200A/ko not_active Withdrawn
- 2007-10-26 SG SG2011077781A patent/SG176419A1/en unknown
- 2007-10-26 CA CA2664914A patent/CA2664914C/en active Active
- 2007-10-26 KR KR1020097010893A patent/KR101520307B1/ko active Active
- 2007-10-26 BR BRPI0718183A patent/BRPI0718183B8/pt active IP Right Grant
- 2007-10-26 EP EP07863555.4A patent/EP2086576B8/en active Active
- 2007-10-26 JP JP2009534896A patent/JP5442442B2/ja active Active
- 2007-10-26 WO PCT/US2007/082699 patent/WO2008052173A2/en not_active Ceased
- 2007-10-26 MY MYPI20091667A patent/MY150226A/en unknown
- 2007-10-26 PT PT07863555T patent/PT2086576E/pt unknown
- 2007-10-26 ES ES07863555T patent/ES2391123T3/es active Active
- 2007-10-26 PL PL07863555T patent/PL2086576T3/pl unknown
- 2007-10-26 SI SI200731036T patent/SI2086576T1/sl unknown
- 2007-10-26 AU AU2007308869A patent/AU2007308869B2/en active Active
-
2009
- 2009-04-27 CO CO09042413A patent/CO6210831A2/es active IP Right Grant
-
2012
- 2012-05-21 US US13/476,405 patent/US8592558B2/en active Active
-
2013
- 2013-08-08 JP JP2013165132A patent/JP2014012008A/ja not_active Withdrawn
- 2013-10-23 US US14/061,249 patent/US9375469B2/en active Active
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