BRPI0718183B8 - proteína hemaglutinina h5 de vírus influenza e seus usos, vacina, seu processo de produção e seus usos, bem como kit de partes - Google Patents

proteína hemaglutinina h5 de vírus influenza e seus usos, vacina, seu processo de produção e seus usos, bem como kit de partes

Info

Publication number
BRPI0718183B8
BRPI0718183B8 BRPI0718183A BRPI0718183A BRPI0718183B8 BR PI0718183 B8 BRPI0718183 B8 BR PI0718183B8 BR PI0718183 A BRPI0718183 A BR PI0718183A BR PI0718183 A BRPI0718183 A BR PI0718183A BR PI0718183 B8 BRPI0718183 B8 BR PI0718183B8
Authority
BR
Brazil
Prior art keywords
well
vaccine
kit
protein
parts
Prior art date
Application number
BRPI0718183A
Other languages
English (en)
Inventor
M Vaughn Eric
Juergen Daemmgen
Carlos Gonzales-Hernandez Paulino
Original Assignee
Boehringer Ingelheim Animal Health Usa Inc
Boehringer Ingelheim Vetmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Animal Health Usa Inc, Boehringer Ingelheim Vetmedica Inc filed Critical Boehringer Ingelheim Animal Health Usa Inc
Publication of BRPI0718183A2 publication Critical patent/BRPI0718183A2/pt
Publication of BRPI0718183B1 publication Critical patent/BRPI0718183B1/pt
Publication of BRPI0718183B8 publication Critical patent/BRPI0718183B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

proteínas h5, moléculas de ácido nucleico e vetores codificando aqueles, e seu uso medicinal. a presente invenção refere-se a novas proteínas h5 hemaglutinina, ácidos nucleicos e vetores codificando aquelas assim como vacinas compreendendo quaisquer de tais proteínas h5, ácidos nucleicos ou vetores codificando aquelas proteínas h5. além disso, a presente invenção também refere-se ao uso medicinal de tais composições em seres humanos e animais.
BRPI0718183A 2006-10-27 2007-10-26 proteína hemaglutinina h5 de vírus influenza e seus usos, vacina, seu processo de produção e seus usos, bem como kit de partes BRPI0718183B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86314206P 2006-10-27 2006-10-27
US60/863,142 2006-10-27
US11/923,326 2007-10-24
US11/923,326 US8202967B2 (en) 2006-10-27 2007-10-24 H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use
PCT/US2007/082699 WO2008052173A2 (en) 2006-10-27 2007-10-26 Novel h5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use

Publications (3)

Publication Number Publication Date
BRPI0718183A2 BRPI0718183A2 (pt) 2013-11-05
BRPI0718183B1 BRPI0718183B1 (pt) 2020-03-17
BRPI0718183B8 true BRPI0718183B8 (pt) 2022-05-24

Family

ID=39325469

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0718183A BRPI0718183B8 (pt) 2006-10-27 2007-10-26 proteína hemaglutinina h5 de vírus influenza e seus usos, vacina, seu processo de produção e seus usos, bem como kit de partes

Country Status (18)

Country Link
US (3) US8202967B2 (pt)
EP (1) EP2086576B8 (pt)
JP (2) JP5442442B2 (pt)
KR (2) KR20150041200A (pt)
AU (1) AU2007308869B2 (pt)
BR (1) BRPI0718183B8 (pt)
CA (1) CA2664914C (pt)
CO (1) CO6210831A2 (pt)
DK (1) DK2086576T3 (pt)
ES (1) ES2391123T3 (pt)
MX (1) MX2009004243A (pt)
MY (1) MY150226A (pt)
PL (1) PL2086576T3 (pt)
PT (1) PT2086576E (pt)
RU (1) RU2479589C2 (pt)
SG (1) SG176419A1 (pt)
SI (1) SI2086576T1 (pt)
WO (1) WO2008052173A2 (pt)

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JOP20190088A1 (ar) 2016-10-21 2019-04-21 Us Agriculture نواقل مؤتلفة للتعبير عن مولدات مضاد فيروس انفلونزا الطيور و استخداماتها
EP3876983A4 (en) * 2018-11-06 2022-08-03 Boehringer Ingelheim Vetmedica GmbH IMMUNOGENIC COMPOSITION AGAINST THE H5 SUBTYPE OF THE AVIAN INFLUENZA VIRUS
CN117229370A (zh) * 2022-06-08 2023-12-15 中科南京生命健康高等研究院 H5n6禽流感广谱性疫苗的开发及其应用

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Also Published As

Publication number Publication date
CO6210831A2 (es) 2010-10-20
CA2664914A1 (en) 2008-05-02
BRPI0718183A2 (pt) 2013-11-05
SG176419A1 (en) 2011-12-29
WO2008052173A9 (en) 2012-03-22
MY150226A (en) 2013-12-31
US20140050755A1 (en) 2014-02-20
JP2014012008A (ja) 2014-01-23
KR101520307B1 (ko) 2015-05-29
US9375469B2 (en) 2016-06-28
WO2008052173A2 (en) 2008-05-02
PL2086576T3 (pl) 2012-12-31
JP2010508030A (ja) 2010-03-18
EP2086576B1 (en) 2012-07-18
EP2086576A2 (en) 2009-08-12
CA2664914C (en) 2016-11-22
RU2479589C2 (ru) 2013-04-20
BRPI0718183B1 (pt) 2020-03-17
SI2086576T1 (sl) 2012-11-30
EP2086576B8 (en) 2015-02-18
DK2086576T3 (da) 2012-10-15
AU2007308869A1 (en) 2008-05-02
EP2086576A4 (en) 2011-01-19
US20120231027A1 (en) 2012-09-13
WO2008052173A3 (en) 2008-11-13
US8202967B2 (en) 2012-06-19
WO2008052173A8 (en) 2011-02-03
KR20150041200A (ko) 2015-04-15
ES2391123T3 (es) 2012-11-21
US20080193471A1 (en) 2008-08-14
MX2009004243A (es) 2009-05-14
AU2007308869B2 (en) 2013-10-24
RU2009119597A (ru) 2010-12-10
JP5442442B2 (ja) 2014-03-12
US8592558B2 (en) 2013-11-26
PT2086576E (pt) 2012-10-11
KR20090078362A (ko) 2009-07-17

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