BRPI0714712B8 - dispositivo para administração de fármaco - Google Patents
dispositivo para administração de fármacoInfo
- Publication number
- BRPI0714712B8 BRPI0714712B8 BRPI0714712A BRPI0714712A BRPI0714712B8 BR PI0714712 B8 BRPI0714712 B8 BR PI0714712B8 BR PI0714712 A BRPI0714712 A BR PI0714712A BR PI0714712 A BRPI0714712 A BR PI0714712A BR PI0714712 B8 BRPI0714712 B8 BR PI0714712B8
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- transmucosal
- buprenorphine
- fentanyl
- devices
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 4
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 abstract 3
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 229960001736 buprenorphine Drugs 0.000 abstract 2
- 229960002428 fentanyl Drugs 0.000 abstract 2
- 230000004888 barrier function Effects 0.000 abstract 1
- 238000009792 diffusion process Methods 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000003232 mucoadhesive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Sheets, Magazines, And Separation Thereof (AREA)
- Friction Gearing (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR122020000250A BR122020000250B8 (pt) | 2006-07-21 | 2007-07-23 | dispositivos para administração de fármaco |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83272606P | 2006-07-21 | 2006-07-21 | |
| US83272506P | 2006-07-21 | 2006-07-21 | |
| US60/832,726 | 2006-07-21 | ||
| US60/832,725 | 2006-07-21 | ||
| US83950406P | 2006-08-23 | 2006-08-23 | |
| US60/839,504 | 2006-08-23 | ||
| PCT/US2007/016634 WO2008011194A2 (en) | 2006-07-21 | 2007-07-23 | Transmucosal delivery devices with enhanced uptake |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0714712A2 BRPI0714712A2 (pt) | 2013-07-16 |
| BRPI0714712B1 BRPI0714712B1 (pt) | 2020-11-17 |
| BRPI0714712B8 true BRPI0714712B8 (pt) | 2021-05-25 |
Family
ID=38819378
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR122020000250A BR122020000250B8 (pt) | 2006-07-21 | 2007-07-23 | dispositivos para administração de fármaco |
| BRPI0714712A BRPI0714712B8 (pt) | 2006-07-21 | 2007-07-23 | dispositivo para administração de fármaco |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR122020000250A BR122020000250B8 (pt) | 2006-07-21 | 2007-07-23 | dispositivos para administração de fármaco |
Country Status (22)
| Country | Link |
|---|---|
| US (13) | US20100015183A1 (OSRAM) |
| EP (3) | EP2054031B1 (OSRAM) |
| JP (2) | JP5448814B2 (OSRAM) |
| KR (2) | KR101230804B1 (OSRAM) |
| CN (2) | CN103550136B (OSRAM) |
| AU (1) | AU2007275581B2 (OSRAM) |
| BR (2) | BR122020000250B8 (OSRAM) |
| CA (1) | CA2658585C (OSRAM) |
| DK (1) | DK2054031T3 (OSRAM) |
| ES (1) | ES2577390T3 (OSRAM) |
| HR (1) | HRP20160405T1 (OSRAM) |
| HU (1) | HUE027395T2 (OSRAM) |
| IL (2) | IL196529A (OSRAM) |
| MX (1) | MX2009000745A (OSRAM) |
| NO (3) | NO340668B1 (OSRAM) |
| NZ (2) | NZ574361A (OSRAM) |
| PL (1) | PL2054031T3 (OSRAM) |
| RS (1) | RS54764B1 (OSRAM) |
| RU (3) | RU2504377C2 (OSRAM) |
| SI (1) | SI2054031T1 (OSRAM) |
| WO (1) | WO2008011194A2 (OSRAM) |
| ZA (1) | ZA200900485B (OSRAM) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
| US7666337B2 (en) | 2002-04-11 | 2010-02-23 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
| US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
| US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US7425292B2 (en) | 2001-10-12 | 2008-09-16 | Monosol Rx, Llc | Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom |
| US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
| US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
| US20110033542A1 (en) * | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
| US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
| US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
| US8663687B2 (en) | 2001-10-12 | 2014-03-04 | Monosol Rx, Llc | Film compositions for delivery of actives |
| US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
| US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
| US8017150B2 (en) | 2002-04-11 | 2011-09-13 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
| CN103550136B (zh) * | 2006-07-21 | 2016-04-13 | 生物递送科学国际公司 | 吸收增强的经粘膜递送装置 |
| EP2063864A4 (en) | 2006-09-20 | 2012-03-14 | Monosol Rx Llc | EDIBLE WATER-SOLUBLE FILM CONTAINING FLAVOR-REDUCING AGENT |
| US8298583B2 (en) | 2007-10-19 | 2012-10-30 | Monosol Rx, Llc | Film delivery system for tetrahydrolipstatin |
| CN105833420A (zh) * | 2008-06-23 | 2016-08-10 | 生物递送科学国际公司 | 多向粘膜给药装置及使用方法 |
| US8282954B2 (en) | 2008-12-15 | 2012-10-09 | Monosol Rx, Llc | Method for manufacturing edible film |
| US9044475B2 (en) | 2009-06-12 | 2015-06-02 | Cynapsus Therapeutics, Inc. | Sublingual apomorphine |
| US8475832B2 (en) * | 2009-08-07 | 2013-07-02 | Rb Pharmaceuticals Limited | Sublingual and buccal film compositions |
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| US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
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| EP2729148A4 (en) | 2011-07-06 | 2015-04-22 | Parkinson S Inst | COMPOSITIONS AND METHOD FOR THE TREATMENT OF SYMPTOMS IN PATIENTS WITH MORBUS PARKINSON |
| ES2660116T3 (es) | 2011-08-18 | 2018-03-20 | Biodelivery Sciences International, Inc. | Dispositivos mucoadhesivos resistentes al uso inadecuado para la administración de buprenorfina |
| EP2915525B1 (en) | 2011-09-19 | 2021-08-11 | Orexo AB | Sublingual abuse-resistant tablets comprising buprenorphine and naloxone |
| EA034529B1 (ru) * | 2011-12-21 | 2020-02-18 | Байоделивери Сайенсиз Интернэшнл, Инк. | Способ лечения хронической боли у субъекта, принимавшего опиоиды, с применением трансмукозального устройства для доставки лекарств |
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| SG11201407081PA (en) | 2012-05-02 | 2014-11-27 | Orexo Ab | New alfentanil composition for the treatment of acute pain |
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| US9839611B2 (en) | 2013-09-10 | 2017-12-12 | Insys Development Company, Inc. | Sublingual buprenorphine spray |
| US9918981B2 (en) | 2013-09-10 | 2018-03-20 | Insys Development Company, Inc. | Liquid buprenorphine formulations |
| US9867818B2 (en) | 2013-09-10 | 2018-01-16 | Insys Development Company, Inc. | Sublingual buprenorphine spray |
| DK3043777T3 (da) | 2013-09-10 | 2020-07-20 | Fresh Cut Dev Llc | Sublingual buprenorphinspray |
| US10722510B2 (en) | 2014-07-08 | 2020-07-28 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
| US10617686B2 (en) | 2014-07-08 | 2020-04-14 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
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| WO2016086095A1 (en) * | 2014-11-25 | 2016-06-02 | Biodelivery Sciences International, Inc. | Patches, methods for forming and testing pharmaceutical agent delivery patches |
| WO2016123406A1 (en) | 2015-01-28 | 2016-08-04 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
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| WO2016172095A1 (en) | 2015-04-21 | 2016-10-27 | Cynapsus Therapeutics, Inc. | Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa |
| CA2998147A1 (en) * | 2015-09-09 | 2017-03-16 | Biodelivery Sciences International, Inc. | Methods of safely transitioning a subject to buprenorphine |
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| US12427121B2 (en) | 2016-05-05 | 2025-09-30 | Aquestive Therapeutics, Inc. | Enhanced delivery epinephrine compositions |
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| US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
| CN105997955B (zh) | 2016-06-28 | 2017-09-12 | 力品药业(厦门)有限公司 | 一种帕洛诺司琼口腔膜剂及其制备方法 |
| CA3049529A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
| KR101912380B1 (ko) * | 2017-03-15 | 2018-10-26 | (주)바이오일레븐 | 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치 |
| EP3691610A1 (en) | 2017-10-07 | 2020-08-12 | Zim Laboratories Limited | Process for the preparation of bi/multi-layer film, multi-layered film produced thereof and apparatus for producing such multi-layer films |
| CA3091443A1 (en) * | 2018-02-22 | 2019-08-29 | Avior, Inc. | Transmucosal film composition and methods of making and using the same |
| CA3101966A1 (en) | 2018-05-29 | 2019-12-05 | Morningside Venture Investments Limited | Drug delivery methods and systems |
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| US12397141B2 (en) | 2018-11-16 | 2025-08-26 | Morningside Venture Investments Limited | Thermally regulated transdermal drug delivery system |
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| US9901539B2 (en) * | 2011-12-21 | 2018-02-27 | Biodelivery Sciences International, Inc. | Transmucosal drug delivery devices for use in chronic pain relief |
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2007
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- 2007-07-23 PL PL07796992.1T patent/PL2054031T3/pl unknown
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- 2007-07-23 EP EP19165171.0A patent/EP3566692A1/en not_active Withdrawn
- 2007-07-23 HU HUE07796992A patent/HUE027395T2/hu unknown
- 2007-07-23 BR BR122020000250A patent/BR122020000250B8/pt active IP Right Grant
- 2007-07-23 BR BRPI0714712A patent/BRPI0714712B8/pt not_active IP Right Cessation
- 2007-07-23 SI SI200731766A patent/SI2054031T1/sl unknown
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2009
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- 2009-01-19 NO NO20090278A patent/NO340668B1/no not_active IP Right Cessation
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2011
- 2011-07-15 US US13/184,306 patent/US8147866B2/en active Active
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2012
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2013
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- 2013-09-06 RU RU2013141051/15A patent/RU2013141051A/ru unknown
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2015
- 2015-06-22 US US14/746,168 patent/US20150366793A1/en not_active Abandoned
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2016
- 2016-06-30 US US15/198,961 patent/US9597288B2/en active Active
- 2016-07-18 US US15/212,912 patent/US9655843B2/en active Active
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2017
- 2017-02-10 US US15/429,385 patent/US20170312218A1/en not_active Abandoned
- 2017-03-14 NO NO20170380A patent/NO344719B1/no not_active IP Right Cessation
- 2017-04-11 US US15/484,682 patent/US20170216278A1/en not_active Abandoned
- 2017-11-01 US US15/801,302 patent/US20190111048A9/en not_active Abandoned
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2019
- 2019-04-25 US US16/394,647 patent/US20190365739A1/en not_active Abandoned
- 2019-06-10 RU RU2019118034A patent/RU2019118034A/ru unknown
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2020
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2021
- 2021-03-22 US US17/209,119 patent/US20210275520A1/en not_active Abandoned
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2023
- 2023-07-03 US US18/346,474 patent/US20240066024A1/en not_active Abandoned
- 2023-09-25 US US18/473,524 patent/US20240156809A1/en not_active Abandoned
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