BRPI0606130A2 - materiais de administração de fármacos feitos através de tecnologia sol/gel - Google Patents
materiais de administração de fármacos feitos através de tecnologia sol/gelInfo
- Publication number
- BRPI0606130A2 BRPI0606130A2 BRPI0606130-3A BRPI0606130A BRPI0606130A2 BR PI0606130 A2 BRPI0606130 A2 BR PI0606130A2 BR PI0606130 A BRPI0606130 A BR PI0606130A BR PI0606130 A2 BRPI0606130 A2 BR PI0606130A2
- Authority
- BR
- Brazil
- Prior art keywords
- drug delivery
- sol
- materials made
- gel technology
- delivery materials
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/0091—Preparation of aerogels, e.g. xerogels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Optics & Photonics (AREA)
- Nanotechnology (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
MATERIAIS DE ADMINISTRAçãO DE FáRMACOS FEITOS ATRAVéS DE TECNOLOGIA SOL/GEL. A presente invenção refere-se a um processo de fabricação de um material de administração de fármacos, o processo compreendendo as etapas de encapsulação de pelo menos um agente biológica e/ou terapeuticamente ativo em uma casca; combinação do agente ativo encapsulado com um sol; e conversão da combinação resultante em um material de administração de fármacos sólido ou semi-sólido. A invenção compreende adicionalmente os materiais de administração de fármacos que podem ser produzidos através de tal processo, bem como implantes médicos compreendendo tais materiais de administração de fármacos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64992705P | 2005-02-03 | 2005-02-03 | |
PCT/EP2006/050622 WO2006082221A1 (en) | 2005-02-03 | 2006-02-02 | Drug delivery materials made by sol/gel technology |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0606130A2 true BRPI0606130A2 (pt) | 2009-06-02 |
Family
ID=36588817
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0606130-3A BRPI0606130A2 (pt) | 2005-02-03 | 2006-02-02 | materiais de administração de fármacos feitos através de tecnologia sol/gel |
Country Status (12)
Country | Link |
---|---|
US (1) | US20060171990A1 (pt) |
EP (1) | EP1845939A1 (pt) |
JP (1) | JP2008528660A (pt) |
KR (1) | KR20070100836A (pt) |
CN (1) | CN101111225A (pt) |
AU (1) | AU2006210267A1 (pt) |
BR (1) | BRPI0606130A2 (pt) |
CA (1) | CA2593043A1 (pt) |
EA (1) | EA012083B1 (pt) |
IL (1) | IL184127A0 (pt) |
MX (1) | MX2007009430A (pt) |
WO (1) | WO2006082221A1 (pt) |
Families Citing this family (80)
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DE102005018059A1 (de) * | 2003-10-24 | 2006-10-26 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zum Verbrücken von Hydroxy- oder Carbonsäuregruppen enthaltenden, organisch polymerisierbaren Silanen oder Silanharzeinheiten, sowie Produkte dieses Verfahrens |
CA2590386A1 (en) * | 2004-12-30 | 2006-07-06 | Cinvention Ag | Combination comprising an agent providing a signal, an implant material and a drug |
DE602005010747D1 (de) | 2005-01-13 | 2008-12-11 | Cinv Ag | Kohlenstoffnanopartikel enthaltende verbundwerkstoffe |
EP1858820A2 (en) * | 2005-03-18 | 2007-11-28 | Cinvention Ag | Process for the preparation of porous sintered metal materials |
CA2612195A1 (en) * | 2005-07-01 | 2007-01-11 | Cinvention Ag | Medical devices comprising a reticulated composite material |
EP1902087A1 (en) * | 2005-07-01 | 2008-03-26 | Cinvention Ag | Process for the production of porous reticulated composite materials |
CN101133312B (zh) * | 2005-12-15 | 2013-07-17 | 杰富意钢铁株式会社 | 钢管的局部压曲性能评价方法、钢管的设计方法、钢管的制造方法和钢管 |
US20070224235A1 (en) | 2006-03-24 | 2007-09-27 | Barron Tenney | Medical devices having nanoporous coatings for controlled therapeutic agent delivery |
US8187620B2 (en) | 2006-03-27 | 2012-05-29 | Boston Scientific Scimed, Inc. | Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents |
GB0606617D0 (en) * | 2006-04-03 | 2006-05-10 | Tsivion Yoram | Hydrophobic formulations |
US20070264303A1 (en) * | 2006-05-12 | 2007-11-15 | Liliana Atanasoska | Coating for medical devices comprising an inorganic or ceramic oxide and a therapeutic agent |
US8815275B2 (en) | 2006-06-28 | 2014-08-26 | Boston Scientific Scimed, Inc. | Coatings for medical devices comprising a therapeutic agent and a metallic material |
US8771343B2 (en) | 2006-06-29 | 2014-07-08 | Boston Scientific Scimed, Inc. | Medical devices with selective titanium oxide coatings |
KR20090041426A (ko) * | 2006-08-11 | 2009-04-28 | 파나세아 바이오테크 리미티드 | 활성제를 전달하기 위한 미립자 및 이의 조제방법 및 조성물 |
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US8394488B2 (en) | 2006-10-06 | 2013-03-12 | Cordis Corporation | Bioabsorbable device having composite structure for accelerating degradation |
US8828419B2 (en) | 2006-10-06 | 2014-09-09 | Cordis Corporation | Bioabsorbable device having encapsulated additives for accelerating degradation |
DE102006048650A1 (de) * | 2006-10-14 | 2008-04-17 | Dot Gmbh | Funktionelle Beschichtung von Implantaten |
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CN107088184B (zh) * | 2017-04-21 | 2020-11-24 | 南京工业大学 | 定向酶促反应系统及其在制备小分子水凝胶中的应用 |
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CN108339148B (zh) * | 2018-02-12 | 2021-03-02 | 华东理工大学 | 一种具有高效凝血功能的介孔二氧化硅基复合微球及其制备方法 |
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WO2019236891A1 (en) * | 2018-06-06 | 2019-12-12 | The Regents Of The University Of California | Photocurable bioink for inkjet 3d pharming |
CN109824901A (zh) * | 2019-03-06 | 2019-05-31 | 青岛科技大学 | 一种强吸水生物相容硅氧烷凝胶及其制备方法 |
US20200298466A1 (en) * | 2019-03-22 | 2020-09-24 | Lawrence Livermore National Security, Llc | Additive manufacture of hierarchically porous materials with high resolution |
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- 2006-02-02 CA CA002593043A patent/CA2593043A1/en not_active Abandoned
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- 2006-02-02 BR BRPI0606130-3A patent/BRPI0606130A2/pt not_active IP Right Cessation
- 2006-02-02 EA EA200701655A patent/EA012083B1/ru unknown
- 2006-02-02 KR KR1020077020054A patent/KR20070100836A/ko not_active Application Discontinuation
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WO2006082221A1 (en) | 2006-08-10 |
IL184127A0 (en) | 2007-10-31 |
MX2007009430A (es) | 2007-08-17 |
EA012083B1 (ru) | 2009-08-28 |
CA2593043A1 (en) | 2006-08-10 |
CN101111225A (zh) | 2008-01-23 |
US20060171990A1 (en) | 2006-08-03 |
EP1845939A1 (en) | 2007-10-24 |
JP2008528660A (ja) | 2008-07-31 |
EA200701655A1 (ru) | 2008-02-28 |
KR20070100836A (ko) | 2007-10-11 |
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