BR9911754A - Copolìmero linear de ciclodextrina, composição terapêutica, composição de ciclodextrina, processos de preparo de um copolìmero linear de ciclodextrina, e de um copolìmero linear de ciclodextrina oxidada, processo para produzir um polìmero reticulado de ciclodextrina, e, processo de tratamento - Google Patents

Copolìmero linear de ciclodextrina, composição terapêutica, composição de ciclodextrina, processos de preparo de um copolìmero linear de ciclodextrina, e de um copolìmero linear de ciclodextrina oxidada, processo para produzir um polìmero reticulado de ciclodextrina, e, processo de tratamento

Info

Publication number
BR9911754A
BR9911754A BR9911754-1A BR9911754A BR9911754A BR 9911754 A BR9911754 A BR 9911754A BR 9911754 A BR9911754 A BR 9911754A BR 9911754 A BR9911754 A BR 9911754A
Authority
BR
Brazil
Prior art keywords
cyclodextrin
linear
copolymer
composition
oxidized
Prior art date
Application number
BR9911754-1A
Other languages
English (en)
Other versions
BR9911754B1 (pt
Inventor
Hector Gonzalez
Suzie Sue Jean Hwang
Mark E Davis
Original Assignee
California Inst Of Techn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Inst Of Techn filed Critical California Inst Of Techn
Publication of BR9911754A publication Critical patent/BR9911754A/pt
Publication of BR9911754B1 publication Critical patent/BR9911754B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

"COPOLìMERO LINEAR DE CICLODEXTRINA, COMPOSIçãO TERAPêUTICA, COMPOSIçãO DE CICLODEXTRINA, PROCESSOS DE PREPARO DE UM COPOLìMERO LINEAR DE CICLODEXTRINA, E DE UM COPOLìMERO LINEAR DE CICLODEXTRINA OXIDADA, PROCESSO PARA PRODUZIR UM POLìMERO RETICULADO DE CICLODEXTRINA, E, PROCESSO DE TRATAMENTO". Descrevem-se copolímeros lineares de ciclodextrina e copolímeros lineares de ciclodextrina oxidada, contendo uma porção de ciclodextrina não oxidada e/ou oxidada integrada na espinha dorsal do polímero. Processos de preparo de tais copolímeros também são descritos. O copolímero linear de ciclodextrina e o copolímero linear de ciclodextrina oxidada da invenção podem ser usados como um veículo de liberação de vários agentes terapêuticos.
BRPI9911754-1A 1998-07-01 1999-06-25 copolìmero linear de ciclodextrina, solúvel em água, composição terapêutica, processo de preparo de um copolìmero linear de ciclodextrina, solúvel em água, e, processo de prepraro de um copolìmero linear de ciclodextrina oxidada, solúvel em água. BR9911754B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9155098P 1998-07-01 1998-07-01
US09/203,556 US6509323B1 (en) 1998-07-01 1998-12-02 Linear cyclodextrin copolymers
PCT/US1999/014298 WO2000001734A1 (en) 1998-07-01 1999-06-25 Linear cyclodextrin copolymers

Publications (2)

Publication Number Publication Date
BR9911754A true BR9911754A (pt) 2001-11-06
BR9911754B1 BR9911754B1 (pt) 2010-07-13

Family

ID=26784076

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9911754-1A BR9911754B1 (pt) 1998-07-01 1999-06-25 copolìmero linear de ciclodextrina, solúvel em água, composição terapêutica, processo de preparo de um copolìmero linear de ciclodextrina, solúvel em água, e, processo de prepraro de um copolìmero linear de ciclodextrina oxidada, solúvel em água.

Country Status (18)

Country Link
US (1) US6509323B1 (pt)
EP (2) EP1093469B1 (pt)
JP (2) JP4741729B2 (pt)
KR (1) KR100851315B1 (pt)
CN (1) CN100365024C (pt)
AT (1) ATE361321T1 (pt)
AU (1) AU763114C (pt)
BR (1) BR9911754B1 (pt)
CA (1) CA2336390C (pt)
CY (1) CY1106797T1 (pt)
DE (1) DE69935982T2 (pt)
DK (2) DK1764112T3 (pt)
ES (2) ES2403416T3 (pt)
HU (1) HU229473B1 (pt)
IL (2) IL140552A0 (pt)
MX (1) MXPA01000206A (pt)
PT (1) PT1093469E (pt)
WO (1) WO2000001734A1 (pt)

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