BR9911754A - Copolìmero linear de ciclodextrina, composição terapêutica, composição de ciclodextrina, processos de preparo de um copolìmero linear de ciclodextrina, e de um copolìmero linear de ciclodextrina oxidada, processo para produzir um polìmero reticulado de ciclodextrina, e, processo de tratamento - Google Patents
Copolìmero linear de ciclodextrina, composição terapêutica, composição de ciclodextrina, processos de preparo de um copolìmero linear de ciclodextrina, e de um copolìmero linear de ciclodextrina oxidada, processo para produzir um polìmero reticulado de ciclodextrina, e, processo de tratamentoInfo
- Publication number
- BR9911754A BR9911754A BR9911754-1A BR9911754A BR9911754A BR 9911754 A BR9911754 A BR 9911754A BR 9911754 A BR9911754 A BR 9911754A BR 9911754 A BR9911754 A BR 9911754A
- Authority
- BR
- Brazil
- Prior art keywords
- cyclodextrin
- linear
- copolymer
- composition
- oxidized
- Prior art date
Links
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 14
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title abstract 14
- 238000000034 method Methods 0.000 title abstract 5
- 229920005684 linear copolymer Polymers 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nanotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medical Informatics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyamides (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Abstract
"COPOLìMERO LINEAR DE CICLODEXTRINA, COMPOSIçãO TERAPêUTICA, COMPOSIçãO DE CICLODEXTRINA, PROCESSOS DE PREPARO DE UM COPOLìMERO LINEAR DE CICLODEXTRINA, E DE UM COPOLìMERO LINEAR DE CICLODEXTRINA OXIDADA, PROCESSO PARA PRODUZIR UM POLìMERO RETICULADO DE CICLODEXTRINA, E, PROCESSO DE TRATAMENTO". Descrevem-se copolímeros lineares de ciclodextrina e copolímeros lineares de ciclodextrina oxidada, contendo uma porção de ciclodextrina não oxidada e/ou oxidada integrada na espinha dorsal do polímero. Processos de preparo de tais copolímeros também são descritos. O copolímero linear de ciclodextrina e o copolímero linear de ciclodextrina oxidada da invenção podem ser usados como um veículo de liberação de vários agentes terapêuticos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9155098P | 1998-07-01 | 1998-07-01 | |
US09/203,556 US6509323B1 (en) | 1998-07-01 | 1998-12-02 | Linear cyclodextrin copolymers |
PCT/US1999/014298 WO2000001734A1 (en) | 1998-07-01 | 1999-06-25 | Linear cyclodextrin copolymers |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9911754A true BR9911754A (pt) | 2001-11-06 |
BR9911754B1 BR9911754B1 (pt) | 2010-07-13 |
Family
ID=26784076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9911754-1A BR9911754B1 (pt) | 1998-07-01 | 1999-06-25 | copolìmero linear de ciclodextrina, solúvel em água, composição terapêutica, processo de preparo de um copolìmero linear de ciclodextrina, solúvel em água, e, processo de prepraro de um copolìmero linear de ciclodextrina oxidada, solúvel em água. |
Country Status (18)
Country | Link |
---|---|
US (1) | US6509323B1 (pt) |
EP (2) | EP1093469B1 (pt) |
JP (2) | JP4741729B2 (pt) |
KR (1) | KR100851315B1 (pt) |
CN (1) | CN100365024C (pt) |
AT (1) | ATE361321T1 (pt) |
AU (1) | AU763114C (pt) |
BR (1) | BR9911754B1 (pt) |
CA (1) | CA2336390C (pt) |
CY (1) | CY1106797T1 (pt) |
DE (1) | DE69935982T2 (pt) |
DK (2) | DK1764112T3 (pt) |
ES (2) | ES2403416T3 (pt) |
HU (1) | HU229473B1 (pt) |
IL (2) | IL140552A0 (pt) |
MX (1) | MXPA01000206A (pt) |
PT (1) | PT1093469E (pt) |
WO (1) | WO2000001734A1 (pt) |
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