BR9807319A - Microgrânulos com liberação controlada, para administração oral, contendo cisplatina, processo de preparação dos mesmos, preparação farmacêutica, e, utilização dos microgrânulos. - Google Patents

Microgrânulos com liberação controlada, para administração oral, contendo cisplatina, processo de preparação dos mesmos, preparação farmacêutica, e, utilização dos microgrânulos.

Info

Publication number
BR9807319A
BR9807319A BR9807319-2A BR9807319A BR9807319A BR 9807319 A BR9807319 A BR 9807319A BR 9807319 A BR9807319 A BR 9807319A BR 9807319 A BR9807319 A BR 9807319A
Authority
BR
Brazil
Prior art keywords
microgranules
controlled release
oral administration
preparation
pharmaceutical preparation
Prior art date
Application number
BR9807319-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Patrice Debregeas
Gerard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm Lab Prod Ethiques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Lab Prod Ethiques filed Critical Ethypharm Lab Prod Ethiques
Publication of BR9807319A publication Critical patent/BR9807319A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR9807319-2A 1997-02-11 1998-02-10 Microgrânulos com liberação controlada, para administração oral, contendo cisplatina, processo de preparação dos mesmos, preparação farmacêutica, e, utilização dos microgrânulos. BR9807319A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9701545A FR2759293B1 (fr) 1997-02-11 1997-02-11 Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
PCT/FR1998/000251 WO1998034599A1 (fr) 1997-02-11 1998-02-10 Microgranules contenant du cisplatine

Publications (1)

Publication Number Publication Date
BR9807319A true BR9807319A (pt) 2000-04-18

Family

ID=9503556

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9807319-2A BR9807319A (pt) 1997-02-11 1998-02-10 Microgrânulos com liberação controlada, para administração oral, contendo cisplatina, processo de preparação dos mesmos, preparação farmacêutica, e, utilização dos microgrânulos.

Country Status (24)

Country Link
US (2) US6458389B1 (en:Method)
EP (1) EP0971702B1 (en:Method)
JP (1) JP4549445B2 (en:Method)
KR (1) KR100471672B1 (en:Method)
AR (1) AR011133A1 (en:Method)
AT (1) ATE255409T1 (en:Method)
BG (1) BG64247B1 (en:Method)
BR (1) BR9807319A (en:Method)
CA (1) CA2282082C (en:Method)
DE (1) DE69820239T2 (en:Method)
DK (1) DK0971702T3 (en:Method)
EA (1) EA001760B1 (en:Method)
ES (1) ES2210726T3 (en:Method)
FR (1) FR2759293B1 (en:Method)
HU (1) HU225425B1 (en:Method)
IL (1) IL131326A (en:Method)
IN (1) IN187998B (en:Method)
NO (1) NO323230B1 (en:Method)
NZ (1) NZ337216A (en:Method)
PL (1) PL191631B1 (en:Method)
PT (1) PT971702E (en:Method)
TW (1) TW561055B (en:Method)
WO (1) WO1998034599A1 (en:Method)
ZA (1) ZA981123B (en:Method)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050096304A1 (en) * 1998-09-08 2005-05-05 David White Method of treating cancer using dithiocarbamate derivatives
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
ATE318585T1 (de) * 1999-05-17 2006-03-15 D B F Pflanzenmaterial enthaltendes granulat und verfahren zur herstellung
BRPI0415242B8 (pt) * 2003-10-10 2021-05-25 Ethypharm Sa microgrânulos de liberação gradual contendo extrato de gingko biloba e o processo para fabricar estes
FR2861990B1 (fr) * 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
JP2008520696A (ja) * 2004-11-18 2008-06-19 ブリストル−マイヤーズ スクイブ カンパニー イキサベピロンを含む腸溶性被覆ビーズおよびその製造
WO2006062072A1 (ja) * 2004-12-10 2006-06-15 Tmrc Co., Ltd. 転移癌治療剤および癌転移抑制剤
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
FR2918566B1 (fr) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
US9700520B2 (en) * 2007-09-21 2017-07-11 Evonik Roehm Gmbh PH-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol
ES2393805T3 (es) * 2007-09-21 2012-12-28 Evonik Röhm Gmbh Composición farmacéutica de liberación controlada dependiente del pH para compuestos no opioides con resistencia frente a la influencia del etanol
ES2626078T3 (es) * 2008-01-10 2017-07-21 Evonik Röhm Gmbh Preparación farmacéutica o nutracéutica revestida con liberación de sustancia activa mejorada en el colon
US20110070302A2 (en) * 2008-01-10 2011-03-24 Evonik Roehm Gmbh Coated pharmaceutical or nutraceutical preparation with accelerated controlled active substance release
DK177529B1 (en) * 2009-10-23 2013-09-08 Bio Bedst Aps Liposomes with improved storage stability
CA2688202C (en) * 2009-12-11 2012-11-13 Bj Services Company Viscoelastic fluids containing hydroxyethyl cellulose
EP2371356B1 (en) * 2010-03-12 2012-12-19 Phoeme GmbH Multi-particle pharmaceutical formulation for colon absorption
US8070047B1 (en) * 2010-12-02 2011-12-06 Rohm And Haas Electronic Materials Llc Flux composition and method of soldering
CN112451486A (zh) 2012-09-04 2021-03-09 埃莱森制药有限责任公司 用顺铂脂质复合物预防癌症的肺部复发
KR20190026962A (ko) 2014-09-05 2019-03-13 심바이오믹스 세러퓨틱스 엘엘씨 세균질증 치료에 사용하기 위한 세크니다졸
WO2016169042A1 (en) * 2015-04-24 2016-10-27 Genedia Biotech Co. Ltd. Combination therapies for bladder cancer
WO2016196653A1 (en) * 2015-06-01 2016-12-08 Symbiomix Therapeutics, Llc Novel nitroimidazole formulations and uses thereof
US11433146B2 (en) 2015-06-12 2022-09-06 Vaxart, Inc. Formulations for small intestinal delivery of RSV and norovirus antigens
TWI795462B (zh) 2017-11-17 2023-03-11 日商鹽野義製藥股份有限公司 光安定性及溶出性優異的醫藥製劑
BR112020021059B1 (pt) 2018-04-24 2022-08-30 Shionogi & Co., Ltd Forma de dosagem sólida
IL278161B2 (en) * 2018-04-24 2024-12-01 Shionogi & Co Solid dosage form with excellent stability
US12280037B2 (en) 2020-09-22 2025-04-22 Evofem Biosciences, Inc. Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3172570D1 (en) * 1981-03-11 1985-11-14 Mirko Beljanski Serpentine, alstonine and sempervirine drugs for the specific inhibition of tumurous and cancerous cells
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
DE3523454A1 (de) * 1985-07-01 1987-01-08 Eberhard Prof Dr Nuernberg Formkoerper
US4925674A (en) * 1988-08-25 1990-05-15 Himedics, Inc. Amoxicillin microencapsulated granules
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
JPH05294839A (ja) * 1992-04-20 1993-11-09 Biomaterial Universe Kk シスプラチン含有生体内分解吸収性高分子の微小球お よびその製造法
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
JPH07112932A (ja) * 1993-08-27 1995-05-02 Mitsui Toatsu Chem Inc 徐放性医薬製剤
JPH0789849A (ja) * 1993-09-20 1995-04-04 Fujisawa Pharmaceut Co Ltd 徐放性製剤
JPH0859460A (ja) * 1994-08-22 1996-03-05 Tanaka Kikinzoku Kogyo Kk 抗ガン剤内包キトサンミクロスフェア及びその製造法
US5637319A (en) * 1995-03-01 1997-06-10 Takada; Kanji Controlled-release preparations
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
PT929293E (pt) * 1996-08-23 2004-03-31 Sequus Pharm Inc Lipossomas contendo um composto de cisplatina

Also Published As

Publication number Publication date
EP0971702B1 (fr) 2003-12-03
HUP0001719A2 (hu) 2000-11-28
PL335107A1 (en) 2000-04-10
AU744001B2 (en) 2002-02-14
DE69820239T2 (de) 2004-10-07
NO993881D0 (no) 1999-08-11
HU225425B1 (en) 2006-11-28
FR2759293A1 (fr) 1998-08-14
CA2282082A1 (fr) 1998-08-13
ES2210726T3 (es) 2004-07-01
PT971702E (pt) 2004-04-30
JP4549445B2 (ja) 2010-09-22
CA2282082C (fr) 2005-10-18
EA199900734A1 (ru) 2000-04-24
HUP0001719A3 (en) 2005-11-28
EA001760B1 (ru) 2001-08-27
EP0971702A1 (fr) 2000-01-19
IN187998B (en:Method) 2002-08-03
KR20000070997A (ko) 2000-11-25
DE69820239D1 (de) 2004-01-15
DK0971702T3 (da) 2004-04-13
AR011133A1 (es) 2000-08-02
IL131326A (en) 2005-03-20
PL191631B1 (pl) 2006-06-30
KR100471672B1 (ko) 2005-03-07
IL131326A0 (en) 2001-01-28
TW561055B (en) 2003-11-11
BG64247B1 (bg) 2004-07-30
US20030017210A1 (en) 2003-01-23
NZ337216A (en) 2000-09-29
WO1998034599A1 (fr) 1998-08-13
NO323230B1 (no) 2007-02-05
ATE255409T1 (de) 2003-12-15
JP2001512433A (ja) 2001-08-21
BG103647A (en) 2000-03-31
US6458389B1 (en) 2002-10-01
ZA981123B (en) 1998-08-20
NO993881L (no) 1999-09-29
FR2759293B1 (fr) 1999-04-30
AU6626798A (en) 1998-08-26

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE NAO ATENDE AOS REQUISITOS NOVIDADE ATIVIDADE INVENTIVA ( ARTS. 8O,10 ( VIII ), 13, 24 E 25 DA LPI 9279/96

B12B Appeal against refusal [chapter 12.2 patent gazette]