BR112018067523A2 - métodos para preparar l-glufosinato - Google Patents

métodos para preparar l-glufosinato

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Publication number
BR112018067523A2
BR112018067523A2 BR112018067523A BR112018067523A BR112018067523A2 BR 112018067523 A2 BR112018067523 A2 BR 112018067523A2 BR 112018067523 A BR112018067523 A BR 112018067523A BR 112018067523 A BR112018067523 A BR 112018067523A BR 112018067523 A2 BR112018067523 A2 BR 112018067523A2
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BR
Brazil
Prior art keywords
glufosinate
methods
preparing
ppo
hydroxy
Prior art date
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BR112018067523A
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English (en)
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BR112018067523A8 (pt
Inventor
Michael Green Brian
Lorraine Gradley Michelle
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Agrimetis Llc
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Publication date
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Publication of BR112018067523A2 publication Critical patent/BR112018067523A2/pt
Publication of BR112018067523A8 publication Critical patent/BR112018067523A8/pt

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    • CCHEMISTRY; METALLURGY
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    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A01N57/20Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
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    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024D-Amino acid oxidase (1.4.3.3)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
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    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
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    • C12P9/00Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
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    • C12YENZYMES
    • C12Y206/00Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01Transaminases (2.6.1)
    • C12Y206/010194-Aminobutyrate—2-oxoglutarate transaminase (2.6.1.19)
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    • C12Y104/00Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03003D-Amino-acid oxidase (1.4.3.3)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
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  • Plant Pathology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

são fornecidos métodos para a produção de l-glufosinato (também conhecido como fosfinotricina ou ácido (s) -2-amino-4- (hidroxi (metil) fosfonoil) butanóico). os métodos compreendem um processo de duas etapas. o primeiro passo envolve a desaminação oxidativa do d-glufosinato em ppo (ácido (2-oxo-4- (hidroxi (metil) fosfinoílo) butírico). o segundo passo envolve a aminação específica de ppo em l-glufosinato, utilizando um grupo amina de um ou mais dadores de amina. combinando estas duas reações, a proporção de l-glufosinato em uma mistura de l-glufosinato e d-glufosinato pode ser substancialmente aumentada.
BR112018067523A 2016-03-02 2017-02-28 Métodos para preparar l-glufosinato BR112018067523A8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662302421P 2016-03-02 2016-03-02
US201662336989P 2016-05-16 2016-05-16
US201662413240P 2016-10-26 2016-10-26
PCT/US2017/019871 WO2017151573A1 (en) 2016-03-02 2017-02-28 Methods for making l-glufosinate

Publications (2)

Publication Number Publication Date
BR112018067523A2 true BR112018067523A2 (pt) 2019-02-05
BR112018067523A8 BR112018067523A8 (pt) 2023-01-31

Family

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BR112018067523A BR112018067523A8 (pt) 2016-03-02 2017-02-28 Métodos para preparar l-glufosinato

Country Status (14)

Country Link
US (7) US9834802B2 (pt)
EP (1) EP3423585A1 (pt)
JP (3) JP7041066B2 (pt)
KR (1) KR20180117154A (pt)
CN (3) CN109072261B (pt)
AU (2) AU2017227553B2 (pt)
BR (1) BR112018067523A8 (pt)
CA (1) CA3015081A1 (pt)
CL (1) CL2018002454A1 (pt)
IL (1) IL261271A (pt)
MA (1) MA43711A (pt)
MX (2) MX2018010425A (pt)
WO (1) WO2017151573A1 (pt)
ZA (1) ZA201805680B (pt)

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