BR112015002131A2 - vacina de vírus sincicial respiratório (rsv) de vírus vaccínia ancara modificado recombinante - Google Patents
vacina de vírus sincicial respiratório (rsv) de vírus vaccínia ancara modificado recombinanteInfo
- Publication number
- BR112015002131A2 BR112015002131A2 BR112015002131A BR112015002131A BR112015002131A2 BR 112015002131 A2 BR112015002131 A2 BR 112015002131A2 BR 112015002131 A BR112015002131 A BR 112015002131A BR 112015002131 A BR112015002131 A BR 112015002131A BR 112015002131 A2 BR112015002131 A2 BR 112015002131A2
- Authority
- BR
- Brazil
- Prior art keywords
- rsv
- virus
- respiratory syncytial
- syncytial virus
- vaccine
- Prior art date
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Abstract
resumo da patente de invenção para: vacina de vírus sincicial respiratório (rsv) de vírus vaccínia ancara modificado recombinante. são fornecidas aqui cepas de vírus de vaccínia modificadas ancara recombinantes (mva) como vacinas melhoradas contra infecção com vírus sincicial respiratório (vírus rsv) e para produtos relacionados, métodos e usos. especificamente, são fornecidos aqui vetores de mva recombinantes geneticamente modificados compreendendo pelo menos uma sequência de nucleotídeos que codifica um determinante antigênico de uma glicoproteína de membrana de rsv e pelo menos uma sequência de nucleotídeo que codifica um determinante antigênico de uma proteína de nucleocapsídeo de rsv. também são fornecidos aqui produtos, métodos e usos dos mesmos, por exemplo, apropriados para afetar uma resposta imune em um sujeito, ou apropriados para diagnosticar uma infecção por rsv, bem como para determinar se um sujeito está em risco de infecção recorrente por rsv.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261678367P | 2012-08-01 | 2012-08-01 | |
US61/678,367 | 2012-08-01 | ||
EP12005594 | 2012-08-01 | ||
EP12005594.2 | 2012-08-01 | ||
PCT/EP2013/055483 WO2014019718A1 (en) | 2012-08-01 | 2013-03-15 | Recombinant modified vaccinia virus ankara (mva) respiratory syncytial virus (rsv) vaccine |
Publications (3)
Publication Number | Publication Date |
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BR112015002131A2 true BR112015002131A2 (pt) | 2017-11-07 |
BR112015002131A8 BR112015002131A8 (pt) | 2022-08-23 |
BR112015002131B1 BR112015002131B1 (pt) | 2022-11-01 |
Family
ID=46614287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015002131-0A BR112015002131B1 (pt) | 2012-08-01 | 2013-03-15 | Vírus vaccinia ankara modificado (mva) recombinante, composição farmacêutica e uso do referido mva recombinante |
Country Status (19)
Country | Link |
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US (6) | US9480738B2 (pt) |
EP (2) | EP2879702B9 (pt) |
JP (2) | JP6523955B2 (pt) |
KR (3) | KR102264852B1 (pt) |
CN (2) | CN109266622B (pt) |
AU (1) | AU2013298915B2 (pt) |
BR (1) | BR112015002131B1 (pt) |
CA (2) | CA2879915C (pt) |
CY (1) | CY1122717T1 (pt) |
EA (2) | EA031453B1 (pt) |
HK (1) | HK1205459A1 (pt) |
IL (1) | IL236744B (pt) |
IN (1) | IN2015DN01448A (pt) |
MX (3) | MX362511B (pt) |
MY (1) | MY171498A (pt) |
NZ (1) | NZ704005A (pt) |
SG (1) | SG11201500696VA (pt) |
SI (1) | SI2879702T1 (pt) |
WO (1) | WO2014019718A1 (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2879702T (pt) * | 2012-08-01 | 2020-02-04 | Bavarian Nordic As | Vacina para o vírus sincicial respiratório (rsv) de vírus vaccinia modificado recombinante ankara (mva) |
BR112015021781A2 (pt) * | 2013-03-15 | 2017-07-18 | Bavarian Nordic As | alta dose única de mva induz uma resposta imune protetora em neonatos e lactentes |
CA2951430A1 (en) | 2014-06-13 | 2015-12-17 | Glaxosmithkline Biologicals Sa | Immunogenic combinations |
US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
US11254711B2 (en) | 2015-06-12 | 2022-02-22 | Glaxosmithkline Biologicals Sa | Adenovirus polynucleotides and polypeptides |
FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
MX2019011869A (es) | 2017-04-04 | 2020-01-09 | Univ Washington | Nanoestructuras proteicas auto-ensamblables que muestran proteinas f de paramixovirus y/o neumovirus y su uso. |
JP2020519666A (ja) | 2017-05-15 | 2020-07-02 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 安定性のウイルス含有組成物 |
AU2018270375A1 (en) | 2017-05-15 | 2019-10-31 | Bavarian Nordic A/S | Stable virus-containing composition |
CN111801342A (zh) | 2017-12-20 | 2020-10-20 | 葛兰素史密丝克莱恩生物有限公司 | 爱泼斯坦-巴尔病毒抗原构建体 |
US11771755B2 (en) | 2018-02-28 | 2023-10-03 | University Of Washington | Self-asssembling nanostructure vaccines |
EP3847246A1 (en) | 2018-09-06 | 2021-07-14 | Bavarian Nordic A/S | Storage improved poxvirus compositions |
WO2020212576A1 (en) * | 2019-04-18 | 2020-10-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Biological and synthetic molecules inhibiting respiratory syncytial virus infection |
CA3148026A1 (en) * | 2019-08-13 | 2021-02-18 | Vyjayanthi Krishnan | Therapeutic agent effectiveness and its route of administration |
IL296250A (en) | 2020-03-12 | 2022-11-01 | Bavarian Nordic As | The compounds that improve the stability of the smallpox virus |
KR20240051214A (ko) | 2021-09-03 | 2024-04-19 | 버베리안 노딕 에이/에스 | 변형 백시니아 바이러스 앙카라(mva)에 의한 세포독성 전이유전자 발현의 하향조절을 위한 마이크로rna의 활용 |
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