MX362511B - Vacuna del virus vaccinia ankara modificado (mva) recombinante para virus sincicial respiratorio (vsr). - Google Patents
Vacuna del virus vaccinia ankara modificado (mva) recombinante para virus sincicial respiratorio (vsr).Info
- Publication number
- MX362511B MX362511B MX2015001479A MX2015001479A MX362511B MX 362511 B MX362511 B MX 362511B MX 2015001479 A MX2015001479 A MX 2015001479A MX 2015001479 A MX2015001479 A MX 2015001479A MX 362511 B MX362511 B MX 362511B
- Authority
- MX
- Mexico
- Prior art keywords
- rsv
- mva
- respiratory syncytial
- virus
- modified vaccinia
- Prior art date
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- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/863—Poxviral vectors, e.g. entomopoxvirus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/065—Poxviridae, e.g. avipoxvirus
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- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
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- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
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- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
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Abstract
La presente invención se refiere a cepas de virus vaccinia Ankara modificado (MVA) recombinante como vacunas mejoradas contra la infección por el virus sincicial respiratorio (virus VSR) y a productos, métodos y usos relacionados. Específicamente, se proporcionan en la presente vectores de MVA recombinante modificados genéticamente que comprenden al menos una secuencia de nucleótidos que codifica un determinante antigénico de una glicoproteína de membrana de VSR y al menos una secuencia de nucleótidos que codifica un determinante antigénico de una proteína de la nucleocápside de VSR. También se proporcionan en la presente productos, métodos y usos de este, por ejemplo, apropiados para provocar una respuesta inmunológica en un sujeto o apropiados para diagnosticar una infección de VSR, así como también para determinar si un sujeto está en riesgo de una infección por VSR recurrente.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261678367P | 2012-08-01 | 2012-08-01 | |
EP12005594 | 2012-08-01 | ||
PCT/EP2013/055483 WO2014019718A1 (en) | 2012-08-01 | 2013-03-15 | Recombinant modified vaccinia virus ankara (mva) respiratory syncytial virus (rsv) vaccine |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015001479A MX2015001479A (es) | 2015-08-12 |
MX362511B true MX362511B (es) | 2019-01-22 |
Family
ID=46614287
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015001479A MX362511B (es) | 2012-08-01 | 2013-03-15 | Vacuna del virus vaccinia ankara modificado (mva) recombinante para virus sincicial respiratorio (vsr). |
MX2019000933A MX2019000933A (es) | 2012-08-01 | 2015-01-30 | Vacuna del virus vaccinia ankara modificado (mva) recombinante para virus sincicial respiratorio (vsr). |
MX2023003746A MX2023003746A (es) | 2012-08-01 | 2015-01-30 | Vacuna del virus vaccinia ankara modificado (mva) recombinante para virus sincicial respiratorio (vsr). |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019000933A MX2019000933A (es) | 2012-08-01 | 2015-01-30 | Vacuna del virus vaccinia ankara modificado (mva) recombinante para virus sincicial respiratorio (vsr). |
MX2023003746A MX2023003746A (es) | 2012-08-01 | 2015-01-30 | Vacuna del virus vaccinia ankara modificado (mva) recombinante para virus sincicial respiratorio (vsr). |
Country Status (19)
Country | Link |
---|---|
US (6) | US9480738B2 (es) |
EP (2) | EP2879702B9 (es) |
JP (2) | JP6523955B2 (es) |
KR (3) | KR102264852B1 (es) |
CN (2) | CN104540520B (es) |
AU (1) | AU2013298915B2 (es) |
BR (1) | BR112015002131B1 (es) |
CA (2) | CA2879915C (es) |
CY (1) | CY1122717T1 (es) |
EA (2) | EA031453B1 (es) |
HK (1) | HK1205459A1 (es) |
IL (1) | IL236744B (es) |
IN (1) | IN2015DN01448A (es) |
MX (3) | MX362511B (es) |
MY (1) | MY171498A (es) |
NZ (1) | NZ704005A (es) |
SG (1) | SG11201500696VA (es) |
SI (1) | SI2879702T1 (es) |
WO (1) | WO2014019718A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2879702T3 (da) * | 2012-08-01 | 2020-02-24 | Bavarian Nordic As | Rekombinant modificeret vacciniavirus ankara (mva)-vaccine mod respiratorisk syncytialvirus (rsv) |
SG10201707340XA (en) * | 2013-03-15 | 2017-10-30 | Bavarian Nordic As | Single high dose of mva induces a protective immune response in neonates and infants |
EP3154576A1 (en) | 2014-06-13 | 2017-04-19 | GlaxoSmithKline Biologicals S.A. | Immunogenic combinations |
US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
CA2988654A1 (en) | 2015-06-12 | 2016-12-15 | Glaxosmithkline Biologicals S.A. | Adenovirus polynucleotides and polypeptides |
FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
CA3058794A1 (en) | 2017-04-04 | 2018-10-11 | University Of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
CN110603058A (zh) | 2017-05-15 | 2019-12-20 | 扬森疫苗与预防公司 | 含有病毒的稳定组合物 |
KR102658198B1 (ko) | 2017-05-15 | 2024-04-16 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정한 바이러스 함유 조성물 |
BR112020012361A2 (pt) | 2017-12-20 | 2020-11-24 | Glaxosmithkline Biologicals S.A. | constructos de antígeno do vírus epstein-barr |
EP3758747A1 (en) | 2018-02-28 | 2021-01-06 | University of Washington | Self-asssembling nanostructure vaccines |
CA3111273C (en) * | 2018-09-06 | 2024-03-26 | Bavarian Nordic A/S | Storage improved poxvirus compositions |
US20220195016A1 (en) * | 2019-04-18 | 2022-06-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Biological and synthetic molecules inhibiting respiratory syncytial virus infection |
KR20220047332A (ko) * | 2019-08-13 | 2022-04-15 | 알티뮨 인크. | 치료제 효과 및 이의 투여 경로 |
CN115243717A (zh) | 2020-03-12 | 2022-10-25 | 巴法里安诺迪克有限公司 | 改善痘病毒稳定性的组合物 |
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