EA201891945A3 - Вакцина рекомбинантного модифицированного вируса осповакцины анкара (mva) респираторно-синцитиального вируса (rsv) - Google Patents

Вакцина рекомбинантного модифицированного вируса осповакцины анкара (mva) респираторно-синцитиального вируса (rsv)

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Publication number
EA201891945A3
EA201891945A3 EA201891945A EA201891945A EA201891945A3 EA 201891945 A3 EA201891945 A3 EA 201891945A3 EA 201891945 A EA201891945 A EA 201891945A EA 201891945 A EA201891945 A EA 201891945A EA 201891945 A3 EA201891945 A3 EA 201891945A3
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Prior art keywords
rsv
virus
mva
respiratory
ospovaczina
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EA201891945A
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EA201891945A2 (ru
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Цедрик Кеминай
Робин Штайгервальд
Пол Чаплин
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Бавариан Нордик А/С
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Publication of EA201891945A2 publication Critical patent/EA201891945A2/ru
Publication of EA201891945A3 publication Critical patent/EA201891945A3/ru

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Abstract

В данной заявке предусмотрены штаммы рекомбинантного модифицированного вируса осповакцины Анкара (MVA) в качестве улучшенной вакцины против инфекции респираторно-синцитиального вируса (вирус RSV) и связанных с ним продуктов, способов и применений. В частности, настоящее изобретение относится к генно-инженерному рекомбинантному вектору MVA, содержащему по меньшей мере одну нуклеотидную последовательность, кодирующую антигенную детерминанту мембранного гликопротеина RSV, и по меньшей мере одну нуклеотидную последовательность, кодирующую антигенную детерминанту нуклеокапсидного белка RSV. Изобретение также относится к продуктам, способам и их применениям, например, пригодным для воздействия на иммунный ответ у субъекта или пригодным для диагностики инфекции RSV, а также определения того, имеется ли опасность рецидива инфекции RSV у субъекта.
EA201891945A 2012-08-01 2013-03-15 Вакцина рекомбинантного модифицированного вируса осповакцины анкара (mva) респираторно-синцитиального вируса (rsv) EA201891945A3 (ru)

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US201261678367P 2012-08-01 2012-08-01
EP12005594 2012-08-01

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EA201891945A3 true EA201891945A3 (ru) 2019-05-31

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EA201891945A EA201891945A3 (ru) 2012-08-01 2013-03-15 Вакцина рекомбинантного модифицированного вируса осповакцины анкара (mva) респираторно-синцитиального вируса (rsv)
EA201590304A EA031453B1 (ru) 2012-08-01 2013-03-15 Рекомбинантный модифицированный вирус осповакцины анкара (mva) и его применение

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DK2879702T3 (da) * 2012-08-01 2020-02-24 Bavarian Nordic As Rekombinant modificeret vacciniavirus ankara (mva)-vaccine mod respiratorisk syncytialvirus (rsv)
EP2968524A1 (en) * 2013-03-15 2016-01-20 Bavarian Nordic A/S Single high dose of mva induces a protective immune response in neonates and infants
EP3888676A1 (en) 2014-06-13 2021-10-06 GlaxoSmithKline Biologicals S.A. Immunogenic combinations
US9630994B2 (en) 2014-11-03 2017-04-25 University Of Washington Polypeptides for use in self-assembling protein nanostructures
MX2017016105A (es) 2015-06-12 2018-05-15 Glaxosmithkline Biologicals Sa Polinucleotidos y polipeptidos de adenovirus.
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