EA201291373A1 - Вакцина и способы для устранения инфекции, вызываемой campylobacter - Google Patents
Вакцина и способы для устранения инфекции, вызываемой campylobacterInfo
- Publication number
- EA201291373A1 EA201291373A1 EA201291373A EA201291373A EA201291373A1 EA 201291373 A1 EA201291373 A1 EA 201291373A1 EA 201291373 A EA201291373 A EA 201291373A EA 201291373 A EA201291373 A EA 201291373A EA 201291373 A1 EA201291373 A1 EA 201291373A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- campylobacter
- methods
- vaccine
- infection caused
- eliminate infection
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Изобретение относится к вакцинным векторам, предназначенным для повышения устойчивости к инфекции, вызываемой Campylobacter, или для усиления иммунного ответа на воздействие Campylobacter, и к способам применения указанных векторов. Вакцинные векторы включают первый полинуклеотид, кодирующий антигенный полипептид, выбираемый из SEQ ID NO:7-9, или его фрагмент. Указанный вектор может также включать иммуностимулирующий полипептид. Указанные способы включают введение пациенту вакцинных векторов по настоящему изобретению.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35303910P | 2010-06-09 | 2010-06-09 | |
PCT/US2011/039832 WO2011156619A2 (en) | 2010-06-09 | 2011-06-09 | Vaccine and methods to reduce campylobacter infection |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201291373A1 true EA201291373A1 (ru) | 2013-05-30 |
EA030793B1 EA030793B1 (ru) | 2018-09-28 |
Family
ID=45098670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201291373A EA030793B1 (ru) | 2010-06-09 | 2011-06-09 | Рекомбинантный вакцинный вектор против инфекции campylobacter и способы усиления иммунного ответа на campylobacter и повышения устойчивости к инфекции campylobacter |
Country Status (22)
Country | Link |
---|---|
US (2) | US8961990B2 (ru) |
EP (2) | EP2579901B1 (ru) |
JP (1) | JP5746333B2 (ru) |
KR (3) | KR102007132B1 (ru) |
CN (1) | CN102971008B (ru) |
AR (1) | AR081856A1 (ru) |
AU (3) | AU2011264772B2 (ru) |
BR (1) | BR112012031211A2 (ru) |
CA (1) | CA2800830C (ru) |
CL (1) | CL2012003458A1 (ru) |
CO (1) | CO6670521A2 (ru) |
DK (1) | DK2579901T3 (ru) |
EA (1) | EA030793B1 (ru) |
ES (1) | ES2753142T3 (ru) |
HU (1) | HUE046858T2 (ru) |
MX (1) | MX350306B (ru) |
NZ (3) | NZ702839A (ru) |
PL (1) | PL2579901T3 (ru) |
PT (1) | PT2579901T (ru) |
UA (2) | UA116915C2 (ru) |
WO (1) | WO2011156619A2 (ru) |
ZA (1) | ZA201209411B (ru) |
Families Citing this family (11)
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US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
DK2525817T3 (en) | 2010-01-21 | 2017-10-02 | Univ Arkansas | Vaccine vectors and methods for enhancing immune responses |
PT2956165T (pt) | 2013-02-14 | 2019-11-29 | Texas A & M Univ Sys | Composições e métodos de potenciação das respostas imunitárias frente a eimeria ou limitação de uma infeção por eimeria |
AU2014239557B2 (en) * | 2013-03-15 | 2019-01-03 | The Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancing immune responses to enteric pathogens |
US9470684B2 (en) * | 2013-08-06 | 2016-10-18 | Techlab, Inc. | Outer membrane protein 18 as a diagnostic marker for campylobacter |
EA201692375A1 (ru) * | 2014-06-05 | 2017-04-28 | Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Арканзас | Антитело-опосредованные вакцины и способы их применения для получения быстрых зрелых иммунных ответов |
CN105223362B (zh) * | 2015-09-10 | 2016-08-31 | 上海慧耘生物科技有限公司 | 空肠弯曲菌酶联免疫检测试剂盒 |
JP7467027B2 (ja) | 2016-05-03 | 2024-04-15 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー | 免疫刺激性ポリペプチドおよび抗原性ポリペプチドを含む酵母ワクチンベクター並びにそれを使用する方法 |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
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2011
- 2011-06-09 NZ NZ702839A patent/NZ702839A/en unknown
- 2011-06-09 NZ NZ604412A patent/NZ604412A/en unknown
- 2011-06-09 EP EP11793174.1A patent/EP2579901B1/en active Active
- 2011-06-09 UA UAA201604997A patent/UA116915C2/uk unknown
- 2011-06-09 UA UAA201300278A patent/UA113496C2/uk unknown
- 2011-06-09 JP JP2013514371A patent/JP5746333B2/ja active Active
- 2011-06-09 KR KR1020187020489A patent/KR102007132B1/ko active IP Right Grant
- 2011-06-09 EA EA201291373A patent/EA030793B1/ru not_active IP Right Cessation
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