BR112012010531A2 - "polipeptídeos de modificação meningocócica fhbp" - Google Patents

"polipeptídeos de modificação meningocócica fhbp"

Info

Publication number
BR112012010531A2
BR112012010531A2 BR112012010531A BR112012010531A BR112012010531A2 BR 112012010531 A2 BR112012010531 A2 BR 112012010531A2 BR 112012010531 A BR112012010531 A BR 112012010531A BR 112012010531 A BR112012010531 A BR 112012010531A BR 112012010531 A2 BR112012010531 A2 BR 112012010531A2
Authority
BR
Brazil
Prior art keywords
fhbp
meningococcal
polypeptides
modification
modification polypeptides
Prior art date
Application number
BR112012010531A
Other languages
English (en)
Portuguese (pt)
Inventor
Banci Lucia
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR112012010531A2 publication Critical patent/BR112012010531A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112012010531A 2009-10-27 2010-10-27 "polipeptídeos de modificação meningocócica fhbp" BR112012010531A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27997709P 2009-10-27 2009-10-27
PCT/IB2010/054865 WO2011051893A1 (en) 2009-10-27 2010-10-27 Modified meningococcal fhbp polypeptides

Publications (1)

Publication Number Publication Date
BR112012010531A2 true BR112012010531A2 (pt) 2019-09-24

Family

ID=43431124

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012010531A BR112012010531A2 (pt) 2009-10-27 2010-10-27 "polipeptídeos de modificação meningocócica fhbp"

Country Status (9)

Country Link
US (2) US20130022633A1 (cg-RX-API-DMAC7.html)
EP (1) EP2493499A1 (cg-RX-API-DMAC7.html)
JP (2) JP5960055B2 (cg-RX-API-DMAC7.html)
CN (1) CN102917730A (cg-RX-API-DMAC7.html)
AU (1) AU2010310985B2 (cg-RX-API-DMAC7.html)
BR (1) BR112012010531A2 (cg-RX-API-DMAC7.html)
CA (1) CA2779816A1 (cg-RX-API-DMAC7.html)
MX (1) MX2012004850A (cg-RX-API-DMAC7.html)
WO (1) WO2011051893A1 (cg-RX-API-DMAC7.html)

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FI2608805T4 (fi) 2010-08-23 2025-08-07 Wyeth Llc NEISSERIA MENINGITIDIS rLP2086 -ANTIGEENIEN STABIILEJA FORMULAATIOITA
CA2809758C (en) 2010-09-10 2021-07-13 Wyeth Llc Non-lipidated variants of neisseria meningitidis orf2086 antigens
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
MX351993B (es) 2012-03-09 2017-11-03 Pfizer Composiciones de neisseria meningitidis y metodos de las mismas.
CN104602704B (zh) * 2012-06-14 2019-08-06 诺华股份有限公司 针对血清组x脑膜炎球菌的疫苗
AU2013295242C1 (en) 2012-07-27 2018-08-09 Institut National De La Sante Et De La Recherche Medicale CD147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
US9764027B2 (en) * 2012-09-18 2017-09-19 Glaxosmithkline Biologicals Sa Outer membrane vesicles
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US20160030544A1 (en) * 2013-03-14 2016-02-04 Isis Innovation Limited Immunogenic composition to neisseria
JP2016527278A (ja) * 2013-08-02 2016-09-08 チルドレンズ ホスピタル アンド リサーチ センター オークランド 天然に生じないh因子結合タンパク質(fhbp)及びその使用の方法
MX380129B (es) 2013-09-08 2025-03-11 Pfizer Composiciones de neisseria meningitidis y sus metodos
SG10201907875TA (en) 2014-02-28 2019-09-27 Glaxosmithkline Biologicals Sa Modified meningococcal fhbp polypeptides
AR102324A1 (es) * 2014-07-17 2017-02-22 Glaxosmithkline Biologicals Sa Polipéptidos fhbp (proteína de unión al factor h) meningocócicos modificados
CN106659776A (zh) 2014-07-17 2017-05-10 葛兰素史密丝克莱恩生物有限公司 脑膜炎球菌疫苗
ES2922554T3 (es) * 2014-07-23 2022-09-16 Childrens Hospital & Res Center At Oakland Variantes de proteínas de unión al factor H y métodos de uso de las mismas
WO2016091902A1 (en) * 2014-12-09 2016-06-16 Sanofi Pasteur Compositions comprising n. meningitidis proteins
CN107249626A (zh) 2015-02-19 2017-10-13 辉瑞大药厂 脑膜炎奈瑟球菌组合物及其方法
GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
WO2018045286A1 (en) 2016-09-02 2018-03-08 Sanofi Pasteur, Inc. Neisseria meningitidis vaccine
EP3312192B1 (en) * 2016-10-24 2023-02-22 BiOMVis Srl Immunogenic compositions containing bacterial outer membrane vesicles
IL267733B2 (en) 2017-01-31 2023-10-01 Pfizer Neisseria meningitidis compositions and methods thereof
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
MX2022003682A (es) 2019-09-27 2022-04-25 Pfizer Composiciones de neisseria meningitidis y metodos de las mismas.
TW202245836A (zh) 2021-02-19 2022-12-01 美商賽諾菲巴斯德公司 重組b型腦膜炎球菌疫苗
TW202423477A (zh) 2022-08-03 2024-06-16 美商賽諾菲巴斯德公司 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物
CN120241991B (zh) * 2025-06-05 2025-12-23 北京绿竹生物技术股份有限公司 一种新型的b群流脑外膜蛋白双功能载体

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AU2010310985A1 (en) 2012-05-24
MX2012004850A (es) 2012-05-22
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WO2011051893A1 (en) 2011-05-05
AU2010310985B2 (en) 2014-11-06
CA2779816A1 (en) 2011-05-05
JP2014503172A (ja) 2014-02-13
CN102917730A (zh) 2013-02-06
US20140348869A1 (en) 2014-11-27
JP2016040302A (ja) 2016-03-24
EP2493499A1 (en) 2012-09-05

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