CA2779816A1 - Modified meningococcal fhbp polypeptides - Google Patents
Modified meningococcal fhbp polypeptides Download PDFInfo
- Publication number
- CA2779816A1 CA2779816A1 CA2779816A CA2779816A CA2779816A1 CA 2779816 A1 CA2779816 A1 CA 2779816A1 CA 2779816 A CA2779816 A CA 2779816A CA 2779816 A CA2779816 A CA 2779816A CA 2779816 A1 CA2779816 A1 CA 2779816A1
- Authority
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- Canada
- Prior art keywords
- seq
- amino acid
- polypeptide
- fhbp
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
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| US27997709P | 2009-10-27 | 2009-10-27 | |
| US61/279,977 | 2009-10-27 | ||
| PCT/IB2010/054865 WO2011051893A1 (en) | 2009-10-27 | 2010-10-27 | Modified meningococcal fhbp polypeptides |
Publications (1)
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| CA2779816A1 true CA2779816A1 (en) | 2011-05-05 |
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| WO (1) | WO2011051893A1 (cg-RX-API-DMAC7.html) |
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| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| LT2411048T (lt) | 2009-03-24 | 2020-06-25 | Glaxosmithkline Biologicals Sa | Adjuvantinį meningokokinį faktorių h surišantis baltymas |
| CA2792683A1 (en) * | 2010-03-10 | 2011-09-15 | Glaxosmithkline Biologicals S.A. | Neisserial fhbp vaccine composition |
| EP2552942B1 (en) | 2010-03-30 | 2017-12-27 | Children's Hospital & Research Center at Oakland | Factor h binding proteins (fhbp) with altered properties and methods of use thereof |
| SI3246044T2 (sl) | 2010-08-23 | 2024-06-28 | Wyeth Llc | Stabilne formulacije antigenov neisseria meningitidis RLP2086 |
| PE20140173A1 (es) | 2010-09-10 | 2014-02-20 | Wyeth Llc | Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| KR101716557B1 (ko) | 2012-03-09 | 2017-03-14 | 화이자 인코포레이티드 | 수막염균 조성물 및 이의 사용 방법 |
| JP2015521595A (ja) | 2012-06-14 | 2015-07-30 | ノバルティス アーゲー | 血清群ｘ髄膜炎菌のためのワクチン |
| CA2875391A1 (en) | 2012-07-27 | 2014-01-30 | Institut National De La Sante Et De La Recherche Medicale | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| US9764027B2 (en) * | 2012-09-18 | 2017-09-19 | Glaxosmithkline Biologicals Sa | Outer membrane vesicles |
| JP6446377B2 (ja) | 2013-03-08 | 2018-12-26 | ファイザー・インク | 免疫原性融合ポリペプチド |
| US20160030544A1 (en) * | 2013-03-14 | 2016-02-04 | Isis Innovation Limited | Immunogenic composition to neisseria |
| BR112016002150A2 (pt) * | 2013-08-02 | 2017-09-12 | Children´S Hospital & Res Center At Oakland | proteínas de ligação de fator h de ocorrência natural (fhbp) e métodos de uso das mesmas |
| MX369534B (es) | 2013-09-08 | 2019-11-11 | Pfizer | Composiciones de neisseria meningitidis y sus metodos. |
| US10392424B2 (en) | 2014-02-28 | 2019-08-27 | Glaxosmithkline Biologicals Sa | Modified meningococcal fHbp polypeptides |
| IL249823B (en) | 2014-07-17 | 2022-07-01 | Glaxosmithkline Biologicals Sa | Meningococcus vaccines |
| AR102324A1 (es) * | 2014-07-17 | 2017-02-22 | Glaxosmithkline Biologicals Sa | Polipéptidos fhbp (proteína de unión al factor h) meningocócicos modificados |
| KR102752259B1 (ko) | 2014-07-23 | 2025-01-13 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 인자 h 결합 단백질 변이체 및 이의 사용 방법 |
| US10232029B2 (en) | 2014-12-09 | 2019-03-19 | Sanofi Pasteur | Compositions comprising N. meningitidis proteins |
| KR20190049940A (ko) | 2015-02-19 | 2019-05-09 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| MX2019002489A (es) | 2016-09-02 | 2019-10-21 | Sanofi Pasteur Inc | Vacuna contra neisseria meningitidis. |
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- 2010-10-27 WO PCT/IB2010/054865 patent/WO2011051893A1/en not_active Ceased
- 2010-10-27 CN CN201080060450XA patent/CN102917730A/zh active Pending
- 2010-10-27 EP EP10782038A patent/EP2493499A1/en not_active Withdrawn
- 2010-10-27 BR BR112012010531A patent/BR112012010531A2/pt not_active IP Right Cessation
- 2010-10-27 AU AU2010310985A patent/AU2010310985B2/en not_active Ceased
- 2010-10-27 MX MX2012004850A patent/MX2012004850A/es unknown
- 2010-10-27 US US13/504,476 patent/US20130022633A1/en not_active Abandoned
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2014
- 2014-07-18 US US14/335,788 patent/US20140348869A1/en not_active Abandoned
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2015
- 2015-10-19 JP JP2015205429A patent/JP2016040302A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2493499A1 (en) | 2012-09-05 |
| CN102917730A (zh) | 2013-02-06 |
| US20140348869A1 (en) | 2014-11-27 |
| JP5960055B2 (ja) | 2016-08-02 |
| WO2011051893A1 (en) | 2011-05-05 |
| BR112012010531A2 (pt) | 2019-09-24 |
| AU2010310985A1 (en) | 2012-05-24 |
| US20130022633A1 (en) | 2013-01-24 |
| MX2012004850A (es) | 2012-05-22 |
| AU2010310985B2 (en) | 2014-11-06 |
| JP2016040302A (ja) | 2016-03-24 |
| JP2014503172A (ja) | 2014-02-13 |
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