BR0208685A - Terapia de imunização à base de peptìdio para tratamento de arteriosclerose e desenvolvimento de ensaio à base de peptìdio para determinação de respostas imunes contra lipoproteìna oxidada de baixa densidade - Google Patents

Terapia de imunização à base de peptìdio para tratamento de arteriosclerose e desenvolvimento de ensaio à base de peptìdio para determinação de respostas imunes contra lipoproteìna oxidada de baixa densidade

Info

Publication number
BR0208685A
BR0208685A BR0208685-9A BR0208685A BR0208685A BR 0208685 A BR0208685 A BR 0208685A BR 0208685 A BR0208685 A BR 0208685A BR 0208685 A BR0208685 A BR 0208685A
Authority
BR
Brazil
Prior art keywords
peptide
development
determination
immunization therapy
immune responses
Prior art date
Application number
BR0208685-9A
Other languages
English (en)
Portuguese (pt)
Inventor
Jan Nilsson
Prediman Shah
Original Assignee
Forskarpatent I Syd Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0101232A external-priority patent/SE0101232D0/xx
Application filed by Forskarpatent I Syd Ab filed Critical Forskarpatent I Syd Ab
Publication of BR0208685A publication Critical patent/BR0208685A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
BR0208685-9A 2001-04-05 2002-04-05 Terapia de imunização à base de peptìdio para tratamento de arteriosclerose e desenvolvimento de ensaio à base de peptìdio para determinação de respostas imunes contra lipoproteìna oxidada de baixa densidade BR0208685A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0101232A SE0101232D0 (sv) 2001-04-05 2001-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based elisa for determination of immune responses against oxidized low density liprotein
SE0103754A SE0103754L (sv) 2001-04-05 2001-11-09 Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
PCT/SE2002/000679 WO2002080954A1 (en) 2001-04-05 2002-04-05 Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein

Publications (1)

Publication Number Publication Date
BR0208685A true BR0208685A (pt) 2004-03-30

Family

ID=26655437

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208685-9A BR0208685A (pt) 2001-04-05 2002-04-05 Terapia de imunização à base de peptìdio para tratamento de arteriosclerose e desenvolvimento de ensaio à base de peptìdio para determinação de respostas imunes contra lipoproteìna oxidada de baixa densidade

Country Status (18)

Country Link
EP (42) EP2295461A1 (https=)
JP (6) JP2004529143A (https=)
CN (4) CN103122031B (https=)
AT (2) ATE510851T1 (https=)
AU (1) AU2002246484B8 (https=)
BR (1) BR0208685A (https=)
CA (3) CA2827167A1 (https=)
CY (1) CY1108817T1 (https=)
DE (1) DE60230029D1 (https=)
DK (3) DK1383526T3 (https=)
EE (2) EE200700052A (https=)
ES (2) ES2317999T3 (https=)
IL (4) IL158285A0 (https=)
PL (4) PL217858B1 (https=)
PT (1) PT1383526E (https=)
RU (1) RU2296582C2 (https=)
SE (1) SE0103754L (https=)
WO (1) WO2002080954A1 (https=)

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US20030105003A1 (en) 2001-04-05 2003-06-05 Jan Nilsson Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
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AU2002362612B2 (en) 2001-09-28 2007-11-15 Cedars-Sinai Medical Center Prevention and treatment of restenosis by local administration of drug
SE0302312D0 (sv) * 2002-10-04 2003-08-27 Forskarpatent I Syd Ab Peptide-based passive immunization therapy for treatment of atherosclerosis
CA2500895A1 (en) * 2002-10-04 2004-04-15 Forskarpatent I Syd Ab Peptide-based passive immunization therapy for treatment of atherosclerosis
SE0302422D0 (sv) 2003-09-11 2003-09-11 Forskarpatent I Syd Ab Peptide-based immunization therapy for treatment of atherosclerosis
SE0400683D0 (sv) * 2004-03-19 2004-03-19 Forskarpatent I Syd Ab Use of modified extracellular matrix proteins in diagnosis and treatment of a atherosclerosis
JP2007531537A (ja) 2004-04-06 2007-11-08 セダーズ−シナイ　メディカル　センター アポリポタンパク質ａ−ｉおよびアポリポタンパク質ａ−ｉｍｉｌａｎｏをコードする組換えアデノ随伴ウイルスベクターによる血管疾患の予防および処置
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US9359633B2 (en) * 2007-11-05 2016-06-07 Nordic Bioscience A/S Biochemical markers for CVD risk assessment
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JP2013510586A (ja) * 2009-11-14 2013-03-28 チュウ、カン−ユウ アテローム性動脈硬化を治療及び／又は予防するための免疫調節方法及びシステム
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RU2013126628A (ru) 2010-11-12 2014-12-20 Седарс-Синаи Медикал Сентер Иммуномодулирующие способы и системы для лечения и/или предотвращения аневризм
CA2817543A1 (en) * 2010-11-12 2012-06-07 Cedars-Sinai Medical Center Immunomodulatory methods and systems for treatment and/or prevention of hypertension
AU2012294431B2 (en) 2011-08-09 2017-03-30 Athera Biotechnologies Ab Antibodies binding to phosphorylcholine (PC) and/or PC conjugates
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BR112015010276A2 (pt) * 2012-11-06 2019-10-15 Hoffmann La Roche peptídeos miméticos
CN103520713B (zh) * 2013-10-16 2015-10-28 西北农林科技大学 一种ApoB100酵母重组疫苗及其制备方法和应用
CN103860470A (zh) * 2014-03-05 2014-06-18 贵州中泰生物科技有限公司 一种口服高密度脂蛋白脂质体的制备方法
CN105315364B (zh) * 2014-06-17 2018-09-18 广州文瑞生物科技有限公司 胶原蛋白vi疫苗预防动脉粥样硬化
CN108135973B (zh) * 2015-05-19 2021-10-19 拉·约拉过敏反应及免疫医学研究所 调节炎症应答及治疗不良心血管事件、病和粥样硬化的人apob100表位、方法和用途
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
CN108478817B (zh) * 2018-03-16 2020-10-27 北京大学 一种动脉粥样硬化检测试剂及其制备方法
US11690912B2 (en) 2018-05-29 2023-07-04 Abcentra, Llc Methods for treatment of rheumatoid arthritis and accelerated atherosclerosis with an anti-Apo B100 antibody
US12016921B2 (en) 2018-05-29 2024-06-25 Abcentra, Llc Methods for treatment of psoriasis with an anti-Apo B100 antibody
CN115025210B (zh) * 2021-03-05 2025-09-05 香港中文大学 减少动脉粥样硬化进展的肽疫苗组合物和药物制剂
CN115025211A (zh) * 2021-11-02 2022-09-09 南京理工大学 用于动脉粥样硬化治疗的纳米疫苗及其制备方法

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Also Published As

Publication number Publication date
EP2295464A1 (en) 2011-03-16
DK2295464T3 (en) 2015-08-17
EP2289917A1 (en) 2011-03-02
AU2002246484A1 (en) 2002-10-21
EP2289914A1 (en) 2011-03-02
JP2008169215A (ja) 2008-07-24
JP5613890B2 (ja) 2014-10-29
EP1383526A1 (en) 2004-01-28
JP2004529143A (ja) 2004-09-24
CN103122031A (zh) 2013-05-29
ES2317999T3 (es) 2009-05-01
EP2289933A1 (en) 2011-03-02
EP2289931A1 (en) 2011-03-02
IL158285A (en) 2009-12-24
JP2011068654A (ja) 2011-04-07
CA2443223A1 (en) 2002-10-17
EP2289926A1 (en) 2011-03-02
EP2289913A1 (en) 2011-03-02
EP2147929A2 (en) 2010-01-27
EP2289916A1 (en) 2011-03-02
EP2289929A1 (en) 2011-03-02
AU2002246484B2 (en) 2007-04-19
EP2289920A1 (en) 2011-03-02
DE60230029D1 (de) 2009-01-08
EP2295458A1 (en) 2011-03-16
IL158285A0 (en) 2004-05-12
JP2009191078A (ja) 2009-08-27
JP5300820B2 (ja) 2013-09-25
EP2289915A1 (en) 2011-03-02
PL367301A1 (en) 2005-02-21
EP2295463A1 (en) 2011-03-16
EP2147680A2 (en) 2010-01-27
EP2289912A1 (en) 2011-03-02
EP2305706A1 (en) 2011-04-06
CN1505525B (zh) 2012-11-07
EP2295461A1 (en) 2011-03-16
EP2006301B1 (en) 2011-05-25
EP2305707A1 (en) 2011-04-06
EP2305708A1 (en) 2011-04-06
EP2289922A1 (en) 2011-03-02
ATE415423T1 (de) 2008-12-15
CY1108817T1 (el) 2014-04-09
EP2295460B1 (en) 2015-06-03
RU2296582C2 (ru) 2007-04-10
EP2289918A1 (en) 2011-03-02
JP2011063598A (ja) 2011-03-31
JP5270456B2 (ja) 2013-08-21
PL215401B1 (pl) 2013-12-31
EP2289935A1 (en) 2011-03-02
ES2546293T3 (es) 2015-09-22
EP1918300A3 (en) 2009-06-17
EP2147930A3 (en) 2010-04-14
EP2295464B1 (en) 2015-06-03
PT1383526E (pt) 2009-02-27
RU2003132443A (ru) 2005-02-27
DK2006301T3 (da) 2011-09-12
IL195356A0 (en) 2009-08-03
EP1383526B1 (en) 2008-11-26
CA2606839A1 (en) 2002-10-17
EP2289919A1 (en) 2011-03-02
PL217858B1 (pl) 2014-08-29
CN101284874B (zh) 2012-10-03
EP2289934B1 (en) 2013-11-13
EP2006301A1 (en) 2008-12-24
EP2289932A1 (en) 2011-03-02
EP2289928A1 (en) 2011-03-02
ATE510851T1 (de) 2011-06-15
CA2827167A1 (en) 2002-10-17
WO2002080954A1 (en) 2002-10-17
CN103122031B (zh) 2015-07-22
EP2289923A1 (en) 2011-03-02
EP2295460A1 (en) 2011-03-16
EP2295459A1 (en) 2011-03-16
JP5300819B2 (ja) 2013-09-25
CN101284874A (zh) 2008-10-15
CA2443223C (en) 2013-11-26
EP2289921A1 (en) 2011-03-02
EP2295457A1 (en) 2011-03-16
EP2289925A1 (en) 2011-03-02
EP2147928A3 (en) 2010-04-14
CN101486766A (zh) 2009-07-22
EP2147929A3 (en) 2010-04-14
EP2295462A1 (en) 2011-03-16
EP2147680A3 (en) 2010-04-14
JP2013144687A (ja) 2013-07-25
SE0103754D0 (sv) 2001-11-09
EP2289924A1 (en) 2011-03-02
EP2289934A1 (en) 2011-03-02
AU2002246484B8 (en) 2007-06-14
EP1918300A2 (en) 2008-05-07
IL188286A0 (en) 2008-03-20
EP2289930A1 (en) 2011-03-02
EE200700052A (et) 2008-08-15
SE0103754L (sv) 2002-10-06
CA2606839C (en) 2015-06-09
PL400308A1 (pl) 2012-12-17
CN1505525A (zh) 2004-06-16
EP2147928A2 (en) 2010-01-27
EP2289927A1 (en) 2011-03-02
EE200300487A (et) 2004-02-16
EP2147930A2 (en) 2010-01-27
DK1383526T3 (da) 2009-03-30

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