CY1108817T1 - Ανοσολογικη θεραπεια για την αντιμετωπιση της αθηροσκληρωσης - Google Patents
Ανοσολογικη θεραπεια για την αντιμετωπιση της αθηροσκληρωσηςInfo
- Publication number
- CY1108817T1 CY1108817T1 CY20091100202T CY091100202T CY1108817T1 CY 1108817 T1 CY1108817 T1 CY 1108817T1 CY 20091100202 T CY20091100202 T CY 20091100202T CY 091100202 T CY091100202 T CY 091100202T CY 1108817 T1 CY1108817 T1 CY 1108817T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- athleticosis
- immunological
- cardiovascular disease
- peptides
- Prior art date
Links
- 230000001900 immune effect Effects 0.000 title 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 2
- 230000000302 ischemic effect Effects 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 101710095342 Apolipoprotein B Proteins 0.000 abstract 1
- 102100040202 Apolipoprotein B-100 Human genes 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Η παρούσα εφεύρεση αφορά σε θραύσματα απολιποπρωτεΐνης Β, συγκεκριμένα σε καθορισμένα πεπτίδια αυτής, για την ανοσοποίηση ή για την θεραπευτική αντιμετώπιση θηλαστικών, συμπεριλαμβανομένου του ανθρώπου, κατά των ισχαιμικών καρδιαγγειακών νόσων, καθώς επίσης και για την διάγνωση της παρουσίας ή της απουσίας αντισωμάτων που συνδέονται με αυξημένο ή μειωμένο κίνδυνο εμφάνισης ισχαιμικών καρδιαγγειακών νόσων, με τη χρήση ενός ή περισσοτέρων από τα εν λόγω πεπτίδια σε μια ELISA (Δοκιμασία ανοσοαπορρόφησης που συνδέεται με ένζυμο).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101232A SE0101232D0 (sv) | 2001-04-05 | 2001-04-05 | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based elisa for determination of immune responses against oxidized low density liprotein |
| SE0103754A SE0103754L (sv) | 2001-04-05 | 2001-11-09 | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| EP02714667A EP1383526B1 (en) | 2001-04-05 | 2002-04-05 | Immunization therapy for treatment of atherosclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108817T1 true CY1108817T1 (el) | 2014-04-09 |
Family
ID=26655437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091100202T CY1108817T1 (el) | 2001-04-05 | 2009-02-24 | Ανοσολογικη θεραπεια για την αντιμετωπιση της αθηροσκληρωσης |
Country Status (18)
| Country | Link |
|---|---|
| EP (42) | EP2289928A1 (el) |
| JP (6) | JP2004529143A (el) |
| CN (4) | CN103122031B (el) |
| AT (2) | ATE510851T1 (el) |
| AU (1) | AU2002246484B8 (el) |
| BR (1) | BR0208685A (el) |
| CA (3) | CA2443223C (el) |
| CY (1) | CY1108817T1 (el) |
| DE (1) | DE60230029D1 (el) |
| DK (3) | DK1383526T3 (el) |
| EE (2) | EE200700052A (el) |
| ES (2) | ES2546293T3 (el) |
| IL (4) | IL158285A0 (el) |
| PL (4) | PL400308A1 (el) |
| PT (1) | PT1383526E (el) |
| RU (1) | RU2296582C2 (el) |
| SE (1) | SE0103754L (el) |
| WO (1) | WO2002080954A1 (el) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030105003A1 (en) | 2001-04-05 | 2003-06-05 | Jan Nilsson | Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein |
| SE0103754L (sv) * | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| PL372925A1 (en) | 2001-09-28 | 2005-08-08 | Esperion Therapeutics Inc. | Prevention and treatment of restenosis by local administration of drug |
| SE0302312D0 (sv) | 2002-10-04 | 2003-08-27 | Forskarpatent I Syd Ab | Peptide-based passive immunization therapy for treatment of atherosclerosis |
| AU2003267905B2 (en) * | 2002-10-04 | 2009-02-05 | Biolnvent International Ab | Peptide-based passive immunization therapy for treatment of atherosclerosis |
| SE0302422D0 (sv) * | 2003-09-11 | 2003-09-11 | Forskarpatent I Syd Ab | Peptide-based immunization therapy for treatment of atherosclerosis |
| SE0400683D0 (sv) * | 2004-03-19 | 2004-03-19 | Forskarpatent I Syd Ab | Use of modified extracellular matrix proteins in diagnosis and treatment of a atherosclerosis |
| US8926958B2 (en) | 2004-04-06 | 2015-01-06 | Cedars-Sinai Medical Center | Prevention and treatment of vascular disease with recombinant adeno-associated virus vectors encoding apolipoprotein A-I and apolipoprotein A-I milano |
| CA2562550C (en) * | 2004-04-15 | 2013-09-24 | Athera Biotechnologies Ab | Phosphorylcholine conjugates and corresponding antibodies |
| EP1676602A1 (en) * | 2005-01-04 | 2006-07-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Continuous administration of epitopes derived from protein present in atherosclerotic plaque for the treatment of atherosclerosis |
| GB0517878D0 (en) | 2005-09-02 | 2005-10-12 | Bioinvent Int Ab | Immunotherapeutic treatment |
| BRPI0720215A2 (pt) * | 2006-12-22 | 2013-12-24 | Abbott Lab | Painel de doença autoimune cardiovascular e métodos de usar o mesmo. |
| WO2008104194A1 (en) * | 2007-02-28 | 2008-09-04 | Bioinvent International Ab | Oxidized ldl and antibodies thereto for the treatment of atheroscleroti c plaques |
| PE20090188A1 (es) | 2007-03-15 | 2009-03-20 | Novartis Ag | Compuestos heterociclicos como moduladores de la senda de hedgehog |
| EP2538221A3 (en) * | 2007-11-05 | 2013-04-24 | Nordic Bioscience A/S | Biochemical markers for CVD risk assessment |
| US20100041663A1 (en) | 2008-07-18 | 2010-02-18 | Novartis Ag | Organic Compounds as Smo Inhibitors |
| EP2319924B1 (en) * | 2008-08-15 | 2016-03-09 | Fujikura Kasei Co., Ltd. | Polypeptide marker for diagnosis of arteriosclerosis, method for detection of arteriosclerosis by using the maker or the like, and kit for diagnosis of arteriosclerosis |
| AU2010319323B2 (en) | 2009-11-14 | 2015-01-15 | Cardiovax, Llc | Immunomodulatory methods and systems for treatment and/or prevention of atherosclerosis |
| US8506964B2 (en) * | 2010-02-05 | 2013-08-13 | Cardiovax, Llc | Fusion proteins and related compositions, methods and systems for treatment and/or prevention of atherosclerosis |
| WO2012024309A2 (en) | 2010-08-18 | 2012-02-23 | Cedars-Sinai Medical Center | Atherosclerosis inhibition via modulation of monocyte-macrophage phenotype using apo a-i milano gene transfer |
| RU2013126888A (ru) * | 2010-11-12 | 2014-12-20 | Седарс-Синаи Медикал Сентер | ИММУНОМОДУЛИРУЮЩИЕ КОМПОЗИЦИИ, СПОСОБЫ И СИСТЕМЫ, СОДЕРЖАЩИЕ ИММУНОГЕННЫЕ ФРАГМЕНТЫ АроВ100 |
| JP2013544243A (ja) | 2010-11-12 | 2013-12-12 | シーダース シナイ メディカル センター | 動脈瘤の治療及び／又は予防のための免疫調節方法及びシステム |
| JP2014516913A (ja) | 2010-11-12 | 2014-07-17 | シーダース シナイ メディカル センター | 高血圧の治療及び／又は予防のための免疫調節方法及びシステム |
| JP6277126B2 (ja) | 2011-08-09 | 2018-02-07 | アセラ・バイオテクノロジーズ・アーベー | ホスホリルコリン（ｐｃ）および／またはｐｃコンジュゲートに結合する抗体 |
| JP6277125B2 (ja) | 2011-08-09 | 2018-02-07 | アセラ・バイオテクノロジーズ・アーベー | ホスホリルコリンに対する新規抗体 |
| RU2495048C1 (ru) * | 2012-04-18 | 2013-10-10 | Андрей Валентинович Исаев | Пептид, обладающий антиатеросклеротическим действием и композиция для профилактики и лечения атеросклероза сосудов |
| EP2917234B1 (en) * | 2012-11-06 | 2020-12-02 | Les Hôpitaux Universitaires de Genève | Mimetic peptides |
| CN103520713B (zh) * | 2013-10-16 | 2015-10-28 | 西北农林科技大学 | 一种ApoB100酵母重组疫苗及其制备方法和应用 |
| CN103860470A (zh) * | 2014-03-05 | 2014-06-18 | 贵州中泰生物科技有限公司 | 一种口服高密度脂蛋白脂质体的制备方法 |
| CN105315364B (zh) * | 2014-06-17 | 2018-09-18 | 广州文瑞生物科技有限公司 | 胶原蛋白vi疫苗预防动脉粥样硬化 |
| EP3297652A4 (en) * | 2015-05-19 | 2019-06-05 | La Jolla Institute for Allergy and Immunology | HUMAN APOB100 EPITOPES, METHOD AND USES FOR MODULATING INFLAMMATORY REACTIONS AND TREATING UNWANTED CARDIOVASCULAR EVENTS, DISEASES AND ATHEROSCLEROSIS |
| US10858422B2 (en) | 2016-05-31 | 2020-12-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
| CN108478817B (zh) * | 2018-03-16 | 2020-10-27 | 北京大学 | 一种动脉粥样硬化检测试剂及其制备方法 |
| WO2019232081A1 (en) | 2018-05-29 | 2019-12-05 | Abcentra, Llc | Compositions and methods for treatment of rheumatoid arthritis and accelerated atherosclerosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970144A (en) | 1984-12-31 | 1990-11-13 | International Genetic Engineering | Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use |
| US5972890A (en) | 1988-05-02 | 1999-10-26 | New England Deaconess Hospital Corporation | Synthetic peptides for arterial imaging |
| WO1993018067A1 (en) * | 1992-03-06 | 1993-09-16 | Abbott Laboratories | Immunocapture assay for direct quantitation of specific lipoprotein cholesterol levels |
| WO1994000592A1 (en) * | 1992-06-26 | 1994-01-06 | Exocell, Inc. | Monoclonal antibodies against glycated low density lipoprotein |
| EP0671926B1 (en) * | 1992-08-11 | 2002-11-13 | President And Fellows Of Harvard College | Immunomodulatory peptides |
| KR0185334B1 (ko) | 1995-11-02 | 1999-04-01 | 김은영 | 인간 혈장 아포지단백질 비-100에 결합하는 생쥐 항체를 암호하는 씨디엔에이 |
| GB9609702D0 (en) * | 1996-05-09 | 1996-07-10 | Royal Free Hosp School Med | Anticoagulant peptides |
| GB9620153D0 (en) * | 1996-09-27 | 1996-11-13 | Univ Strathclyde | Non-naturally occurring lipoprotein particle |
| GB9705831D0 (en) * | 1997-03-20 | 1997-05-07 | Univ Leicester | Oxidised ldl |
| US6635623B1 (en) * | 1997-06-13 | 2003-10-21 | Baylor College Of Medicine | Lipoproteins as nucleic acid vectors |
| US6225070B1 (en) | 1997-08-07 | 2001-05-01 | The Regents Of The University Of California | Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma |
| US6156315A (en) * | 1997-10-10 | 2000-12-05 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting the binding of low density lipoprotein to blood vessel matrix |
| EP0911344B1 (en) * | 1997-10-15 | 2004-03-03 | Fujirebio Inc. | Anti-Apo-B-48 monoclonal antibody, hybridoma, and methods of use |
| CA2323056A1 (en) * | 1998-03-10 | 1999-09-16 | Regents Of The University Of California | Methods and tools for identifying compounds which modulate atherosclerosis by impacting ldl-proteoglycan binding |
| AU5200699A (en) * | 1998-07-13 | 2000-02-01 | University Of Otago | Inhibition of lipoprotein formation |
| IL126447A (en) * | 1998-10-04 | 2004-09-27 | Vascular Biogenics Ltd | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
| AU773370B2 (en) * | 1999-10-26 | 2004-05-20 | Regents Of The University Of California, The | Reagents and methods for diagnosing, imaging and treating atherosclerotic disease |
| AU2001236589A1 (en) * | 2000-02-04 | 2001-08-14 | Aeomica, Inc. | Methods and apparatus for high-throughput detection and characterization of alternatively spliced genes |
| IL151355A0 (en) * | 2000-03-03 | 2003-04-10 | Smithkline Beecham Biolog | Vaccine for the treatment of artherosclerosis |
| SE0000855D0 (sv) * | 2000-03-15 | 2000-03-15 | Karolinska Innovations Ab | Antigenic composition useful as a vaccine against atherosclerosis |
| GB0017641D0 (en) * | 2000-07-18 | 2000-09-06 | Medigene Oy | Peptides and their use |
| EP1186299A1 (en) * | 2000-09-12 | 2002-03-13 | Universitair Medisch Centrum Utrecht | The diagnosis, prevention, and/or succesful treatment of atherosclerosis, infectious diseases, and disturbances in the immune system |
| JP2004529080A (ja) * | 2000-10-25 | 2004-09-24 | アグネッロ，ヴィンセント | Ｈｃｖ、他のフラビウイルス科ウイルス、および血液中で低密度リポタンパク質または超低密度リポタンパク質と複合体を形成するその他のあらゆるウイルスによる感染を細胞中へのウイルス侵入を抑制することによって防止する方法 |
| AU2002241603A1 (en) * | 2000-11-10 | 2002-06-03 | University Of Utah Research Foundation | Carrier system for specific artery wall gene delivery |
| SE0103754L (sv) * | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| US7241861B2 (en) * | 2001-05-15 | 2007-07-10 | Japan Immunoresearch Laboratories Co., Ltd. | High density lipoprotein-reactive peptides |
| WO2003007689A2 (en) * | 2001-07-20 | 2003-01-30 | Eidgenoessische Technische Hochschule Zurich (Ethz) | Compositions and methods for use of bioactive agents derived from sulfated and sulfonated amino acids |
-
2001
- 2001-11-09 SE SE0103754A patent/SE0103754L/xx not_active Application Discontinuation
-
2002
- 2002-04-05 CA CA2443223A patent/CA2443223C/en not_active Expired - Lifetime
- 2002-04-05 IL IL15828502A patent/IL158285A0/xx unknown
- 2002-04-05 ES ES10181267.5T patent/ES2546293T3/es not_active Expired - Lifetime
- 2002-04-05 CA CA2827167A patent/CA2827167A1/en not_active Abandoned
- 2002-04-05 EP EP10181196A patent/EP2289928A1/en not_active Withdrawn
- 2002-04-05 EP EP10181227A patent/EP2289932A1/en not_active Withdrawn
- 2002-04-05 EP EP10180193A patent/EP2289917A1/en not_active Withdrawn
- 2002-04-05 EP EP10181213A patent/EP2289930A1/en not_active Withdrawn
- 2002-04-05 DE DE60230029T patent/DE60230029D1/de not_active Expired - Lifetime
- 2002-04-05 RU RU2003132443/15A patent/RU2296582C2/ru active
- 2002-04-05 EP EP10180106A patent/EP2289912A1/en not_active Withdrawn
- 2002-04-05 EP EP10181253.5A patent/EP2289934B1/en not_active Expired - Lifetime
- 2002-04-05 JP JP2002578993A patent/JP2004529143A/ja not_active Withdrawn
- 2002-04-05 DK DK02714667T patent/DK1383526T3/da active
- 2002-04-05 EP EP08167533A patent/EP2147930A3/en not_active Withdrawn
- 2002-04-05 WO PCT/SE2002/000679 patent/WO2002080954A1/en active Application Filing
- 2002-04-05 EP EP10180156A patent/EP2295459A1/en not_active Withdrawn
- 2002-04-05 EP EP10181188A patent/EP2289927A1/en not_active Withdrawn
- 2002-04-05 PL PL400308A patent/PL400308A1/pl unknown
- 2002-04-05 PL PL385189A patent/PL215401B1/pl unknown
- 2002-04-05 EP EP10180826A patent/EP2289920A1/en not_active Withdrawn
- 2002-04-05 CN CN201210322795.9A patent/CN103122031B/zh not_active Expired - Lifetime
- 2002-04-05 AT AT08151489T patent/ATE510851T1/de not_active IP Right Cessation
- 2002-04-05 EP EP10181167A patent/EP2289925A1/en not_active Withdrawn
- 2002-04-05 EP EP10180026A patent/EP2295457A1/en not_active Withdrawn
- 2002-04-05 EP EP08151489A patent/EP2006301B1/en not_active Expired - Lifetime
- 2002-04-05 EP EP10180168A patent/EP2295461A1/en not_active Withdrawn
- 2002-04-05 EP EP10180823A patent/EP2289919A1/en not_active Withdrawn
- 2002-04-05 EP EP10180184A patent/EP2295462A1/en not_active Withdrawn
- 2002-04-05 EP EP10180188A patent/EP2289916A1/en not_active Withdrawn
- 2002-04-05 EP EP10180172A patent/EP2289915A1/en not_active Withdrawn
- 2002-04-05 ES ES02714667T patent/ES2317999T3/es not_active Expired - Lifetime
- 2002-04-05 EP EP10180176A patent/EP2305708A1/en not_active Withdrawn
- 2002-04-05 PL PL391615A patent/PL217858B1/pl unknown
- 2002-04-05 EP EP10180111A patent/EP2289914A1/en not_active Withdrawn
- 2002-04-05 EP EP08158141A patent/EP2147928A3/en not_active Withdrawn
- 2002-04-05 CA CA2606839A patent/CA2606839C/en not_active Expired - Lifetime
- 2002-04-05 EP EP10181217A patent/EP2289931A1/en not_active Withdrawn
- 2002-04-05 EP EP10180109A patent/EP2289913A1/en not_active Withdrawn
- 2002-04-05 EP EP08167531A patent/EP2147929A3/en not_active Ceased
- 2002-04-05 BR BR0208685-9A patent/BR0208685A/pt not_active Application Discontinuation
- 2002-04-05 EP EP10181263A patent/EP2295463A1/en not_active Withdrawn
- 2002-04-05 EP EP10180115A patent/EP2305707A1/en not_active Withdrawn
- 2002-04-05 CN CN028089405A patent/CN1505525B/zh not_active Expired - Fee Related
- 2002-04-05 EP EP10181203A patent/EP2289929A1/en not_active Withdrawn
- 2002-04-05 DK DK10181267.5T patent/DK2295464T3/en active
- 2002-04-05 EP EP10180199A patent/EP2289918A1/en not_active Withdrawn
- 2002-04-05 AT AT02714667T patent/ATE415423T1/de active
- 2002-04-05 EE EEP200700052A patent/EE200700052A/xx unknown
- 2002-04-05 EP EP10180099A patent/EP2295458A1/en not_active Withdrawn
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