ATE263189T1 - Antikörper gegen menschliches prostatspezifisches drüsenkallikrein - Google Patents

Antikörper gegen menschliches prostatspezifisches drüsenkallikrein

Info

Publication number
ATE263189T1
ATE263189T1 AT94922047T AT94922047T ATE263189T1 AT E263189 T1 ATE263189 T1 AT E263189T1 AT 94922047 T AT94922047 T AT 94922047T AT 94922047 T AT94922047 T AT 94922047T AT E263189 T1 ATE263189 T1 AT E263189T1
Authority
AT
Austria
Prior art keywords
antibodies
human prostate
specific
gland kallikrein
kallikrein
Prior art date
Application number
AT94922047T
Other languages
English (en)
Inventor
Donald J Tindall
Charles Y F Young
George G Klee
Original Assignee
Mayo Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation filed Critical Mayo Foundation
Application granted granted Critical
Publication of ATE263189T1 publication Critical patent/ATE263189T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT94922047T 1993-07-22 1994-06-29 Antikörper gegen menschliches prostatspezifisches drüsenkallikrein ATE263189T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/096,946 US5516639A (en) 1993-07-22 1993-07-22 Antibodies specific for human prostate glandular kallkrein
PCT/US1994/007329 WO1995003334A1 (en) 1993-07-22 1994-06-29 Antibodies specific for human prostate glandular kallikrein

Publications (1)

Publication Number Publication Date
ATE263189T1 true ATE263189T1 (de) 2004-04-15

Family

ID=22259880

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94922047T ATE263189T1 (de) 1993-07-22 1994-06-29 Antikörper gegen menschliches prostatspezifisches drüsenkallikrein

Country Status (11)

Country Link
US (1) US5516639A (de)
EP (1) EP0710253B1 (de)
JP (1) JPH09501152A (de)
AT (1) ATE263189T1 (de)
AU (1) AU693457B2 (de)
DE (1) DE69433663T2 (de)
DK (1) DK0710253T3 (de)
ES (1) ES2215997T3 (de)
PT (1) PT710253E (de)
WO (1) WO1995003334A1 (de)
ZA (1) ZA945364B (de)

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US5786148A (en) * 1996-11-05 1998-07-28 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a novel prostate-specific kallikrein
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US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
WO1995030758A1 (en) * 1994-05-10 1995-11-16 Mayo Foundation For Medical Education And Research Recombinant hk2 polypeptide
US5614372A (en) * 1995-02-24 1997-03-25 Lilja; Hans Early detection of prostate cancer (CAP) by employing prostate specific antigen (PSA) and human glandular kallikrein (hGK-1)
US5807978A (en) * 1995-06-07 1998-09-15 Kokolus; William J. Immunogenic peptides of prostate specific antigen
GB2302874B (en) * 1995-06-29 1999-11-10 Orion Yhtymae Oy Novel proteins
US6143509A (en) * 1996-02-06 2000-11-07 Abbott Laboratories Prostate specific antigen peptides and uses thereof
US6946133B1 (en) * 1996-03-20 2005-09-20 The United States Of America As Represented By The Department Of Health And Human Services Prostate specific antigen oligo-epitope peptide
EP0974057B1 (de) * 1996-07-15 2005-09-21 Mayo Foundation For Medical Education And Research Verfahren zur detektion der hk2 polypeptide
AU4086397A (en) * 1996-09-06 1998-03-26 Centocor Inc. Monoclonal antibodies specific for prostate specific antigen and methods of detecting prostate specific antigen
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
US5840871A (en) * 1997-01-29 1998-11-24 Incyte Pharmaceuticals, Inc. Prostate-associated kallikrein
AU8259798A (en) * 1997-06-20 1999-01-04 George G Klee Method for detection of breast cancer
US6280742B1 (en) 1998-06-17 2001-08-28 Zonagen, Inc. Methods and materials for the treatment of prostatic carcinoma
CA2360073C (en) 1999-01-28 2011-01-18 Gen-Probe Incorporated Probes and primers for detecting prostate specific antigen (psa) in a biological sample
US7195759B2 (en) * 2001-06-06 2007-03-27 The University Of Manitoba Therapeutic uses of glandular kallikrein
US20090162342A1 (en) * 2001-06-07 2009-06-25 Sanomune Inc. Therapeutic uses of glandular kallikrein
TWI247012B (en) * 2001-07-19 2006-01-11 Akzo Nobel Nv Process for rapid solution synthesis of peptides
IL150600A (en) * 2001-07-19 2005-09-25 Akzo Nobel Nv Process for the preparation of compounds containing one or more amide bonds using an excess of an activated carboxylic component and scavenging the residual activated carboxylic component
US20040009503A1 (en) * 2002-07-03 2004-01-15 Molecular Staging, Inc. Immune modulatory activity of human ribonucleases
CA2514089A1 (en) * 2002-11-18 2004-06-03 The Johns Hopkins University Activation of peptide prodrugs by hk2
US8663600B2 (en) * 2005-02-17 2014-03-04 Diaprost Ab Diagnosis of prostate cancer
EP2152417B1 (de) 2007-05-04 2018-07-11 Opko Diagnostics, LLC Vorrichtung und methode für analysen in mikrofluidsysteme
ES2695039T3 (es) * 2009-02-02 2018-12-28 Opko Diagnostics, Llc Estructuras para controlar la interacción de luz con dispositivos microfluídicos
US20130116131A1 (en) 2011-11-08 2013-05-09 Caldera Health Limited Methods and materials for the diagnosis of prostate cancers
US8658164B2 (en) 2011-11-08 2014-02-25 Caldera Health Limited Methods and materials for the diagnosis of prostate cancers
US8658166B2 (en) 2011-11-08 2014-02-25 Caldera Health Limited Methods and materials for the diagnosis of prostate cancers
TWI596494B (zh) 2012-03-05 2017-08-21 Ｏｐｋｏ診斷法有限責任公司 預測前列腺癌風險及前列腺腺體體積之方法及裝置
US20130315891A1 (en) 2012-05-25 2013-11-28 Matthew Charles Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
EP2854841B1 (de) 2012-06-04 2017-02-22 Diamedica Inc. Kallikrein-1-glycosylierungsisoformen aus menschlichem gewebe
KR102505543B1 (ko) 2014-03-28 2023-03-02 옵코 다이어그노스틱스, 엘엘씨 전립선암 진단에 관한 조성물 및 방법
US12326453B2 (en) 2014-03-28 2025-06-10 Opko Diagnostics, Llc Compositions and methods for active surveillance of prostate cancer
PT3253800T (pt) 2015-03-27 2021-04-28 Opko Diagnostics Llc Padrões de antigénio da próstata e suas utilizações
CN110446501A (zh) 2017-03-09 2019-11-12 代阿麦迪卡股份有限公司 组织激肽释放酶1的剂型
IL309179A (en) * 2021-06-10 2024-02-01 Janssen Biotech Inc Nucleic acid coding for KLK2-GPI fusion protein, recombinant cells and their uses

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WO1995030758A1 (en) * 1994-05-10 1995-11-16 Mayo Foundation For Medical Education And Research Recombinant hk2 polypeptide

Also Published As

Publication number Publication date
AU7252594A (en) 1995-02-20
DE69433663D1 (de) 2004-05-06
ZA945364B (en) 1995-03-13
AU693457B2 (en) 1998-07-02
DE69433663T2 (de) 2004-08-19
EP0710253B1 (de) 2004-03-31
ES2215997T3 (es) 2004-10-16
JPH09501152A (ja) 1997-02-04
PT710253E (pt) 2004-07-30
EP0710253A1 (de) 1996-05-08
US5516639A (en) 1996-05-14
WO1995003334A1 (en) 1995-02-02
DK0710253T3 (da) 2004-07-26

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