CA2165672A1 - Antibodies specific for human prostate glandular kallikrein - Google Patents

Antibodies specific for human prostate glandular kallikrein

Info

Publication number
CA2165672A1
CA2165672A1 CA002165672A CA2165672A CA2165672A1 CA 2165672 A1 CA2165672 A1 CA 2165672A1 CA 002165672 A CA002165672 A CA 002165672A CA 2165672 A CA2165672 A CA 2165672A CA 2165672 A1 CA2165672 A1 CA 2165672A1
Authority
CA
Canada
Prior art keywords
human prostate
antibodies specific
glandular kallikrein
prostate glandular
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002165672A
Other languages
French (fr)
Other versions
CA2165672C (en
Inventor
Donald J. Tindall
Charles Y. F. Young
George G. Klee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayo Foundation for Medical Education and Research
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/096,946 external-priority patent/US5516639A/en
Application filed by Individual filed Critical Individual
Publication of CA2165672A1 publication Critical patent/CA2165672A1/en
Application granted granted Critical
Publication of CA2165672C publication Critical patent/CA2165672C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention provides an isolated preparation of monoclonal or polyclonal antibodies which react specifically with human prostate-specific glandular kallikrein (hK2), but which do not cross-react with human prostate-specific antigen (PSA), as well as immunogenic hK2 antigens useful to provide such antibodies.
CA002165672A 1993-07-22 1994-06-29 Antibodies specific for human prostate glandular kallikrein Expired - Lifetime CA2165672C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/096,946 1993-07-22
US08/096,946 US5516639A (en) 1993-07-22 1993-07-22 Antibodies specific for human prostate glandular kallkrein
PCT/US1994/007329 WO1995003334A1 (en) 1993-07-22 1994-06-29 Antibodies specific for human prostate glandular kallikrein

Publications (2)

Publication Number Publication Date
CA2165672A1 true CA2165672A1 (en) 1995-02-02
CA2165672C CA2165672C (en) 2007-05-15

Family

ID=38069003

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002165672A Expired - Lifetime CA2165672C (en) 1993-07-22 1994-06-29 Antibodies specific for human prostate glandular kallikrein

Country Status (1)

Country Link
CA (1) CA2165672C (en)

Also Published As

Publication number Publication date
CA2165672C (en) 2007-05-15

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20140630